Assessing BRAFV600E Expression in Malignant Melanoma
This cross-sectional study describes use of VE1 immunohistochemical analysis to assess the presence of BRAFV600E mutations in tumor specimens from patients with cutaneous malignant melanoma. (Source: JAMA Oncology)
Source: JAMA Oncology - January 15, 2015 Category: Cancer & Oncology Authors: Hanna Eriksson, MD, PhD and colleagues Tags: JAMA Dermatology Original Investigation Research Source Type: research
Trend Analysis of Primary Tumor Resection for CRC
This population epidemiology study using SEER registry data characterizes patterns of primary tumor resection for patients with stage IV colorectal cancer in the United States ... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 15, 2015 Category: Cancer & Oncology Authors: Chung-Yuan Hu, MPH, PhD and colleagues Tags: JAMA Surgery Original Investigation Research Source Type: research
Exceptional Opportunities in Medical Science
As the world’s largest source of biomedical research funding, the US National Institutes of Health (NIH) has been advancing understanding of health and disease for ... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 15, 2015 Category: Cancer & Oncology Authors: Francis S. Collins, MD, PhD Tags: JAMA Opinion Viewpoint Source Type: research
Supporting Biomedical Research
The Howard Hughes Medical Institute (HHMI) has spent 60 years experimenting and learning how to support biomedical research effectively. From the time Mr Hughes first ... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 15, 2015 Category: Cancer & Oncology Authors: Robert Tjian, PhD Tags: JAMA Opinion Viewpoint Source Type: research
The Anatomy of Medical Research
This Special Communication characterizes national investments in and outputs of medical research in the US and internationally. (Source: JAMA Oncology)
Source: JAMA Oncology - January 15, 2015 Category: Cancer & Oncology Authors: Hamilton Moses III, MD and colleagues Tags: Clinical Review & Education Featured Clinical Review JAMA Special Communication Source Type: research
IGSF4 Methylation and Oropharyngeal Cancer
This cohort study reports that methylation of IGSF4 is associated with human papillomavirus–positive status in patients with oropharyngeal squamous cell carcinoma. (Source: JAMA Oncology)
Source: JAMA Oncology - January 8, 2015 Category: Cancer & Oncology Authors: Kang Mei Chen, MD and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research
Prognostic Value of Keratinization in Oropharyngeal SCC
This cohort study investigates association between keratinization of oropharyngeal squamous cell carcinoma and survival. (Source: JAMA Oncology)
Source: JAMA Oncology - January 8, 2015 Category: Cancer & Oncology Authors: Timothy Cooper, MD and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research
Tracheal Mass
A 50-year-old female presented to the emergency department with progressive dyspnea and worsening stridor. Awake flexible bronchoscopy under local anesthesia revealed a purple, pedunculated mass... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 8, 2015 Category: Cancer & Oncology Authors: Patricia Purcell, MD and colleagues Tags: Clinical Problem Solving Clinical Review & Education JAMA Otolaryngology—Head & Neck Surgery Source Type: research
Validation of Uveal Melanoma Classification
This cohort study characterizes outcomes for patients with uveal melanoma by American Joint Committee on Cancer tumor stage. (Source: JAMA Oncology)
Source: JAMA Oncology - January 2, 2015 Category: Cancer & Oncology Authors: The AJCC Ophthalmic Oncology Task Force Tags: JAMA Ophthalmology Original Investigation Research Source Type: research
Increasing Varenicline Dose in Smokers
This randomized trial reports that increasing varenicline dose in smokers with initial low response to the drug had no effect on tobacco withdrawal symptoms or... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 2, 2015 Category: Cancer & Oncology Authors: Peter Hajek, PhD and colleagues Tags: JAMA Internal Medicine Original Investigation Research Source Type: research
Clinical Variability of Ocular Involvement in Mycosis Fungoides
Importance Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma and may rarely infiltrate the ocular structures. Ophthalmic findings in MF can... » (Source: JAMA Oncology)
Source: JAMA Oncology - January 2, 2015 Category: Cancer & Oncology Authors: Denis Jusufbegovic, MD and Devron H. Char, MD Tags: Brief Report JAMA Ophthalmology Research Source Type: research
Minor Salivary Gland Basal Cell Adenocarcinoma
This case report describes a patient with salivary gland basal cell adenocarcinoma and reviews other published case reports. (Source: JAMA Oncology)
Source: JAMA Oncology - January 2, 2015 Category: Cancer & Oncology Authors: David W. Cuthbertson, MD and colleagues Tags: Clinical Review & Education JAMA Otolaryngology—Head & Neck Surgery Source Type: research
Entecavir vs Lamivudine to Prevent HBV
This randomized trial reports a lower incidence of hepatitis B virus (HBV) infection and reactivation in patients with untreated diffuse large B-cell lymphoma who were... » (Source: JAMA Oncology)
Source: JAMA Oncology - December 18, 2014 Category: Cancer & Oncology Authors: He Huang, MD and colleagues Tags: Featured Research JAMA Original Investigation Source Type: research
Surgical Localization of Axillary Lymph Nodes
This report describes successful image-guided localization and resection of lymph nodes containing known metastases in patients with breast cancer who had a clip placed in... » (Source: JAMA Oncology)
Source: JAMA Oncology - December 18, 2014 Category: Cancer & Oncology Authors: Abigail S. Caudle, MD, MS and colleagues Tags: JAMA Surgery Original Investigation Research Source Type: research
Tobacco Cessation Outreach
This randomized clinical trial evaluates a proactive tobacco cessation program that addresses sociocontextual mediators of tobacco use for low-socioeconomic-status smokers. (Source: JAMA Oncology)
Source: JAMA Oncology - December 18, 2014 Category: Cancer & Oncology Authors: Jennifer S. Haas, MD, MSc and colleagues Tags: JAMA Internal Medicine Original Investigation Research Source Type: research
