International Review of Neurobiology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Stress, cortisol and suicide risk
This article presents an overview of studies that demonstrate that stress and dysregulated hypothalamic-pituitary-adrenal (HPA) axis activity, as measured by cortisol levels, are important additional risk factors for suicide. Evidence for other putative stress-related suicide risk factors including childhood trauma, impaired executive function, impulsivity and disrupted sleep are considered together with the impact of family history of suicide, perinatal and epigenetic influences on suicide risk. (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - January 28, 2020 Category: Neuroscience Source Type: research
Is there neuroinflammation in depression? Understanding the link between the brain and the peripheral immune system in depression
We describe the concept of microglial activation as a marker of neuroinflammation and the potential use of anti-inflammatory treatments in depression. The paper concludes by highlighting the unresolved questions and challenges for future studies. (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - January 28, 2020 Category: Neuroscience Source Type: research
Salivary cortisol as a non-invasive window on the brain
Publication date: Available online 10 January 2020Source: International Review of NeurobiologyAuthor(s): Angela Clow, Nina SmythAbstractThe validation of accurate and meaningful assessment of cortisol in saliva samples has proved revolutionary in stress research. Its many advantages have expanded the scope of investigation from traditional laboratory and clinical settings to include multidisciplinary and community-based research. These developments have given rise to a wealth insight into the links between stress and health. Here we highlight the potential of salivary cortisol as both a product and mediator of brain functi...
Source: International Review of Neurobiology - January 11, 2020 Category: Neuroscience Source Type: research
The impact of childhood poverty on brain health: Emerging evidence from neuroimaging across the lifespan
Publication date: Available online 18 December 2019Source: International Review of NeurobiologyAuthor(s): Alexander J. Dufford, Pilyoung Kim, Gary W. EvansAbstractExperiencing poverty in childhood has been associated with increased risk for physical and mental health difficulties later in life. An emerging body of evidence suggests that brain development may be one mediator of this relation. In this chapter, we discuss evidence for an association between childhood poverty and brain structure/function. First, we examine the association from a lifespan perspective discussing studies at multiple developmental stages from the ...
Source: International Review of Neurobiology - December 18, 2019 Category: Neuroscience Source Type: research
Effects of stress on the structure and function of the medial prefrontal cortex: Insights from animal models
Publication date: Available online 14 December 2019Source: International Review of NeurobiologyAuthor(s): Cara L. Wellman, Justin L. Bollinger, Kelly M. MoenchAbstractStress alters both cognitive and emotional function, and increases risk for a variety of psychological disorders, such as depression and posttraumatic stress disorder. The prefrontal cortex is critical for executive function and emotion regulation, is a target for stress hormones, and is implicated in many stress-influenced psychological disorders. Therefore, understanding how stress-induced changes in the structure and function of the prefrontal cortex are r...
Source: International Review of Neurobiology - December 15, 2019 Category: Neuroscience Source Type: research
Prenatal stress: Effects on fetal and child brain development
Publication date: Available online 14 December 2019Source: International Review of NeurobiologyAuthor(s): Alexandra Lautarescu, Michael C. Craig, Vivette GloverAbstractThe impact of stress on brain health begins in the womb. Both animal and human studies have found that prenatal maternal stress affects the brain and behavior of the offspring. Stressful life events, exposure to a natural disaster, and symptoms of maternal anxiety and depression increase the risk for the child having a range of emotional, behavioral and/or cognitive problems in later life. These include depression, anxiety, Attention Deficit Hyperactivity Di...
Source: International Review of Neurobiology - December 15, 2019 Category: Neuroscience Source Type: research
Chronic stress, structural exposures and neurobiological mechanisms: A stimulation, discrepancy and deprivation model of psychosis
Publication date: Available online 5 December 2019Source: International Review of NeurobiologyAuthor(s): Teresa Vargas, Rachel E. Conley, Vijay A. MittalAbstractChronic stress exposure has been established as a key vulnerability factor for developing psychotic disorders, including schizophrenia. A structural, or systems level perspective, has often been lacking in conceptualizations of chronic stress for psychotic disorders. The current review thus identified three subtypes of structural exposures. Stimulation exposures included urban environments, population density and crime exposure, with intermediary mechanisms of lack...
Source: International Review of Neurobiology - December 6, 2019 Category: Neuroscience Source Type: research
Social prescribing for stress related disorders and brain health
Publication date: Available online 5 December 2019Source: International Review of NeurobiologyAuthor(s): Alison Fixsen, Marie PolleyAbstractSocial prescribing allows health professionals to refer at risk patients toward health and wellbeing interventions and activities in the local community. It is a key part of NHS (National Health Service) England health care policy, and schemes based on the social prescribing model have been developed in countries including Canada, New Zealand, the Netherlands and Singapore. In this chapter, we consider the role that social prescribing can play in reducing stress related problems and su...
Source: International Review of Neurobiology - December 6, 2019 Category: Neuroscience Source Type: research
The development of stress reactivity and regulation during human development
Publication date: Available online 29 November 2019Source: International Review of NeurobiologyAuthor(s): Melissa L. Engel, Megan R. GunnarAbstractAdverse experiences during childhood can have long-lasting impacts on physical and mental health. At the heart of most theories of how these effects are transduced into health impacts is the activity of stress-mediating systems, most notably the hypothalamic-pituitary-adrenocortical (HPA) axis. Here we review the anatomy and physiology of the axis, models of stress and development, the development of the axis prenatally through adolescence, the role of experience and sensitive p...
Source: International Review of Neurobiology - November 30, 2019 Category: Neuroscience Source Type: research
Preface
Publication date: 2019Source: International Review of Neurobiology, Volume 149Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - November 27, 2019 Category: Neuroscience Source Type: research
International Review of Neurobiology
Publication date: 2019Source: International Review of Neurobiology, Volume 149Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - November 27, 2019 Category: Neuroscience Source Type: research
Front Matter
Publication date: 2019Source: International Review of Neurobiology, Volume 149Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - November 27, 2019 Category: Neuroscience Source Type: research
Copyright
Publication date: 2019Source: International Review of Neurobiology, Volume 149Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - November 27, 2019 Category: Neuroscience Source Type: research
Contributors
Publication date: 2019Source: International Review of Neurobiology, Volume 149Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - November 27, 2019 Category: Neuroscience Source Type: research
