Microbiological profile of infections of the hip joint: An Indian perspective
Conclusion: Staphylococcus sp. was the most common pathogen found in hip infections. However, the high incidence of Gram-negative infection requires that prophylactic antibiotics cover these organisms as well. The high resistance to first-line antibiotics should be taken into consideration while making protocols. The knowledge of the microbial profile is especially important when considering arthroplasty for arthritis secondary to hip infections. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: A Arunshankar VJ Chandy Divyaa Elangovan TD Hariharan John Antony Jude Prakash Rahul George Anil T Oommen Pradeep M Poonnoose Source Type: research

Comparative evaluation of microscan walkaway 96 plus ID/AST system and mikrolatest broth microdilution kit in assessing In vitro colistin susceptibility of carbapenem-resistant clinical gram-negative bacterial isolates: Experience from a tertiary care teaching hospital in Rishikesh, Uttarakhand
Conclusions: Data generated by this study will be of help to the clinicians who are often faced with the dilemma of treating multi drug resistant infections with limited treatment options. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Ravi Indrapal Singh Mohit Bhatia KR Anusha Vanya Singh Balram Ji Omar Pratima Gupta Source Type: research

Effectiveness of hand hygiene promotional program based on the WHO multimodal hand hygiene improvement strategy, in terms of compliance and decontamination efficacy in an indian tertiary level neonatal surgical intensive care unit
Conclusion: To the best of our knowledge, this is the first study about the effect of implementation of the WHO MHHIS from an Indian hospital. HHPP was found to be effective in terms of HH compliance and decontamination efficacy. Its implementation is highly recommended to promote HH in a developing country like India. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Alphonsa Muth Thomas Sukhwinder Kaur Manisha Biswal KL N Rao Shashi Vig Source Type: research

Performance of three commercial assays for colistin susceptibility in clinical isolates and Mcr-1 carrying reference strain
Conclusion: Micronaut-S was found to be an acceptable method for colistin AST. In contrast, E-test was unreliable in terms of EA. Vitek-2 was found to be reliable for colistin AST, although it was more prone to CE near the colistin breakpoints. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Chand Wattal Neeraj Goel Jaswinder Kaur Oberoi Sanghamitra Datta Reena Raveendran Source Type: research

A comparative assessment of clinical, pharmacological and antimicrobial profile of novel anti-methicillin-resistant Staphylococcus aureus agent levonadifloxacin: Therapeutic role in nosocomial and community infections
Yamuna Devi Bakthavatchalam, Shoma Vinay Rao, Barney Isaac, Abi Manesh, Senthur Nambi, Subramanian Swaminathan, Vasanth Nagvekar, Vivek Nangia, Peter Victor John, Balaji VeeraraghavanIndian Journal of Medical Microbiology 2019 37(4):478-487Staphylococcus aureus is of significant clinical concern in both community- and hospital-onset infections. The key to the success of S. aureus as a pathogen is its ability to swiftly develop antimicrobial resistance. Methicillin-resistant S. aureus (MRSA) is not only resistant to nearly all beta-lactams but also demonstrates resistance to several classes of antibiotics. A high prevalence...
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Yamuna Devi Bakthavatchalam Shoma Vinay Rao Barney Isaac Abi Manesh Senthur Nambi Subramanian Swaminathan Vasanth Nagvekar Vivek Nangia Peter Victor John Balaji Veeraraghavan Source Type: research

Novel 2019-coronavirus on new year & #39;s Eve
Parakriti Gupta, Kapil Goyal, Poonam Kanta, Arnab Ghosh, Mini P SinghIndian Journal of Medical Microbiology 2019 37(4):459-477An ongoing apocalyptic outbreak of a new virus causing pneumonia-like clusters in Wuhan city, China, has gleamed the world. The outbreak, confirmed on the New Year's Eve 2020, has known no boundaries since then. The number has surpassed that of Severe Acute Respiratory Syndrome (SARS) and Middle East respiratory syndrome (MERS), and is uninterruptedly escalating. Being an RNA virus, it has a propensity to mutate due to the low proofreading capacity of RNA-dependent RNA polymerase. Step-wi...
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Parakriti Gupta Kapil Goyal Poonam Kanta Arnab Ghosh Mini P Singh Source Type: research

Erratum: Abstracts - Indian journal of medical microbiology - supplement 1 - 2019 - Volume 37
Indian Journal of Medical Microbiology 2019 37(3):457-458 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Source Type: research

Fungal infection in a post-renal transplant patient with Diaporthe
K Vichitra, Lokeshwari Gopal, Balajee Govindarao, V Chandrasekaran, Anupma Jyoti KindoIndian Journal of Medical Microbiology 2019 37(3):454-456 Post-renal transplant fungal infections continue to be a major cause of mortality and morbidity. Universally reported fungi are Candida, especially Candida albicans, Cryptococcus, Aspergillus, Trichophyton rubrum and Pityriasis versicolor. Here, we report a case of infection caused by a rare fungus Diaporthe. It is an endophyte reported as plant pathogens and infrequently in humans and mammals. The patient was a renal transplant recipient on immunosuppressant. He had hypothyroidis...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: K Vichitra Lokeshwari Gopal Balajee Govindarao V Chandrasekaran Anupma Jyoti Kindo Source Type: research

Paradoxical upgradation response in non-HIV tuberculosis: Report of two cases
Meghana Nathani Kabra, Thrinadh KunapareddyIndian Journal of Medical Microbiology 2019 37(3):450-453 A paradoxical upgradation response in tuberculosis (TB) is defined as the worsening of a pre-existing tubercular lesion or the appearance of a new lesion in a patient whose clinical symptoms initially improved with anti-TB treatment. A paradoxical response is common in HIV patients in the form of immune reconstitution inflammatory syndrome. A similar kind of response can also be seen in immunocompetent patients. Here, we present two cases of non-HIV TB who initially improved with antitubercular therapy (ATT) but worsened t...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Meghana Nathani Kabra Thrinadh Kunapareddy Source Type: research

Utility of Xpert & #174; MTB/RIF in the diagnosis of extrapulmonary tuberculosis
Vidya Krishna, Ram Gopalakrishnan, Anil Tarigopula, Senthur Nambi Panchatcharam, Suresh Kumar Dorairajan, Ramasubramanian VenkatasubramanianIndian Journal of Medical Microbiology 2019 37(3):448-449 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Vidya Krishna Ram Gopalakrishnan Anil Tarigopula Senthur Nambi Panchatcharam Suresh Kumar Dorairajan Ramasubramanian Venkatasubramanian Source Type: research

Group B Streptococcus vaginal colonisation in pregnant women at a tertiary care hospital in Mumbai
Shalmali Deshpande, Tanu Singhal, Suchitra N Pandit, Sweta ShahIndian Journal of Medical Microbiology 2019 37(3):446-447 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Shalmali Deshpande Tanu Singhal Suchitra N Pandit Sweta Shah Source Type: research

Determination of Biofilm-Forming Capacity of Otopathogens Isolated from Discharging Ears in Children with Chronic Otitis Media
This study describes the microorganisms isolated from the middle ear and nasopharynx of children with chronically discharging ears. Middle ear and nasopharyngeal swabs from 89 children were studied, and the microorganisms isolated were assessed for biofilm-forming ability. Methicillin-susceptible Staphylococcus aureus was common in the nasopharynx, while the middle ear showed predominantly pseudomonas and Methicillin-resistant S. aureus. Pseudomonas aeruginosa showed strong biofilm formation, whereas Escherichia coli, Proteus sp. and Providentia sp. were weak biofilm producers. S. aureus isolates were negative for biofilm ...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Zoremsangi Ralte P Naina Anushree Amladi Mary John Shalini Anndan Ajoy Mathew Varghese Source Type: research

Phylogenetic diversity of Orientia tsutsugamushi isolates in patients with scrub typhus in Bengaluru, India
Sneha K Chunchanur, Shwetha J Venugopal, R Ambica, B DakshayaniIndian Journal of Medical Microbiology 2019 37(3):438-441 Scrub typhus has re-emerged as an important cause of acute febrile illness in India. There is a dearth of information on strain diversity of Orientia tsutsugamushi from Karnataka, India, hence the present study sought to address this issue. One hundred clinically suspected cases of scrub typhus/rickettsiosis (as per the DHR-ICMR guidelines) were included. Nested-polymerase chain reaction (PCR) for 56-kDa gene and phylogenetic analysis was performed. PCR was positive in 22 cases and phylogenetic analysis...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Sneha K Chunchanur Shwetha J Venugopal R Ambica B Dakshayani Source Type: research

Utility of QuantiFERON & #174;-TB gold In-Tube test compared with tuberculin skin test in diagnosing tuberculosis in Indian children with malnutrition
Deepthi Boddu, Valsan Philip Verghese, Joy Sarojini Michael, Anila Chacko, Visali JeyaseelanIndian Journal of Medical Microbiology 2019 37(3):433-437 This prospective cohort study was conducted to compare the accuracy of QuantiFERON®-TB (QFT) Gold In-Tube test and tuberculin skin test (TST) in diagnosing tuberculosis (TB) in predominantly bacille Calmette–Guerin-vaccinated children with a high incidence of malnutrition. The sensitivity of the QFT versus the TST was 69.6% versus 52.9% for WHO-defined TB, with specificity of 86% versus 78.3%, respectively....
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Deepthi Boddu Valsan Philip Verghese Joy Sarojini Michael Anila Chacko Visali Jeyaseelan Source Type: research

Melioidosis in Odisha: A clinico-microbiological and epidemiological description of culture-confirmed cases over a 2-year period
Bijayini Behera, Srujana Mohanty, Ashoka Mahapatra, Vinay Kumar Hallur, Baijayantimala Mishra, Anupam Dey, Rajesh Kumar, Tushar K Mishra, Prakash K Sasmal, Mithilesh Sinha, Prasanta R Mohapatra, Manoj K Panigrahi, C Preetam, Rashmi Ranjan DasIndian Journal of Medical Microbiology 2019 37(3):430-432 Melioidosis is an emerging infectious disease in India mostly reported from South-western coastal Karnataka and North-eastern Tamil Nadu. We speculate the existence of another major hidden focus in Odisha, one of the eastern coastal states. The clinico-epidemiological features of 47 culture-confirmed melioidosis at a tertiary c...
Source: Indian Journal of Medical Microbiology - January 28, 2020 Category: Microbiology Authors: Bijayini Behera Srujana Mohanty Ashoka Mahapatra Vinay Kumar Hallur Baijayantimala Mishra Anupam Dey Rajesh Kumar Tushar K Mishra Prakash K Sasmal Mithilesh Sinha Prasanta R Mohapatra Manoj K Panigrahi C Preetam Rashmi Ranjan Das Source Type: research