Indian Journal of Medical Microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Dual therapy with lopinavir/ritonavir plus lamivudine could be a viable alternative for antiretroviral-therapy-naive adults with HIV-1 infection regardless of HIV viral load or subgenotype in resource-limited settings: A randomised, open-label and non-inferiority study from China
Conclusion: The results suggest that dual therapy of LPV/r plus 3TC is non-inferior to the first-line triple-therapy regimen in China. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Linghua Li Haolan He Yun Lan Jinfeng Chen Huolin Zhong Jingmin Nie Xiejie Chen Fengyu Hu Xiaoping Tang Weiping Cai Source Type: research

A road less travelled: Clinical comparison of HIV seropositive and seronegative patients with cystoisosporiasis & #8211; An 11-year experience from a tertiary care centre in Northern India
Conclusion: The epidemiology of cystoisosporiasis differs between HIV seropositive and seronegative patients in terms of year-wise and month-wise trends, co-infections and most importantly, AECs. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Ujjala Ghoshal Vidhi Jain Nidhi Tejan Sonali Khanduja Kalra Prabhat Ranjan Richa Sinha Dinesh Gangwar Uday C Ghoshal Source Type: research

Validation of pneumococcal iron acquisition (piaA) gene for accurate identification of Streptococcus pneumoniae
Conclusions: PiaA-PCR can be used as a specific marker for the identification of pneumococcus, though it is less sensitive. As the level of agreement was moderate, further analyses on a large number of samples can give conclusive evidence for its use as a diagnostic marker for pneumococcus. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Sreeram Chandra Murthy Peela Sujatha Sistla Kadhiravan Tamilarasu Sriram Krishnamurthy B Adhishivam Source Type: research

Characterization of In vitro inhibitory effects of consensus short interference RNAs against non-structural 5B gene of hepatitis C virus 1a genotype
Conclusions: Stable Huh-7 cells persistently expressing NS5B protein should be helpful for molecular pathogenesis of HCV infection and development of anti-HCV drug screening assays. The siRNA was effective against NS5B and could be considered as an adjuvant therapy along with other promising anti-HCV regimens. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Imran Shahid Waleed Hassan Almalki Munjed M Ibrahim Sultan Ahmad Alghamdi Mohammed H Mukhtar Shaia Saleh R. Almalki Saad Ahmed Alkahtani Mohammad S Alhaidari Source Type: research

Multidrug-resistant Enterobacteriaceae colonising the gut of adult rural population in South India
Conclusions: Carriage of MDR strains with a potential to express multidrug resistance poses a threat of dissemination in the community. Awareness for restricted use of antibiotics and proper sanitation can contain the spread of resistant bacteria. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Sherly Antony Kandasamy Ravichandran Reba Kanungo Source Type: research

Prosthetic joint infection: A major threat to successful total joint arthroplasty
Sujeesh Sebastian, Rajesh Malhotra, Benu DhawanIndian Journal of Medical Microbiology 2018 36(4):475-487Total joint arthroplasty (TJA) is one of the most common and reliable orthopaedic procedures that has significantly improved the quality of life of patients with degenerative joint diseases. Following the increase in the ageing population, availability of trained orthopaedic surgeons and advances in implantation procedures, demand for TJA both globally and in India is significantly increasing. Though TJA is one of the most cost-successful orthopaedic procedures, prosthetic joint infection (PJI) is one of the major compli...
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Sujeesh Sebastian Rajesh Malhotra Benu Dhawan Source Type: research

Pneumococcal vaccines
Anand Manoharan, Ranjith JayaramanIndian Journal of Medical Microbiology 2018 36(4):465-474Streptococcus pneumoniae continues to take a heavy toll on childhood mortality and morbidity across the developing world. An estimated 10.6 million invasive pneumococcal diseases (IPDs) occur every year, with nearly 1 million deaths in children under 5 years of age. Introduction of vaccines in the childhood immunisation programme in developed world has brought down the incidence of the disease considerably. However, childhood immunocompromising illnesses including HIV have increased the risk of IPD several folds. There is also a grow...
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Anand Manoharan Ranjith Jayaraman Source Type: research

Respiratory syncytial virus infections in India: Epidemiology and need for vaccine
Shobha Broor, Shama Parveen, Megha MaheshwariIndian Journal of Medical Microbiology 2018 36(4):458-464Respiratory syncytial virus (RSV) has been identified as a leading cause of lower respiratory tract infections in young children and elderly. It is an enveloped negative-sense RNA virus belonging to Genus Orthopneumovirus. The clinical features of RSV infection range from mild upper-respiratory-tract illnesses or otitis media to severe lower-respiratory-tract illnesses. Current estimates show that about 33.1 million episodes of RSV-acute lower respiratory infection (ALRI) occurred in young children in 2015, of these majori...
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Shobha Broor Shama Parveen Megha Maheshwari Source Type: research

IAMM recommended modification of MD microbiology curriculum to MD clinical microbiology as a speciality of medicine under consideration of MCI and Niti Ayog: Time has come to move on! Are we ready ?
Chand WattalIndian Journal of Medical Microbiology 2018 36(4):453-457 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 17, 2019 Category: Microbiology Authors: Chand Wattal Source Type: research

Cutaneous botryomycosis of the foot: A case report and review of literature
Kevin John, Karthik Gunasekaran, Thomas Alex Kodiatte, Ramya IyyaduraiIndian Journal of Medical Microbiology 2018 36(3):447-449Botryomycosis is a chronic bacterial infection that manifests clinically as tumours or plaques that are often ulcerated and have discharging sinuses draining small white-coloured granules. Therefore, they closely mimic mycetoma or other fungal infections. It is most commonly caused by Staphylococcus aureus. It can present as cutaneous or visceral disease. The cutaneous form can invade deep tissue leading to extensive destruction and disfigurement. A 31-year-old female presented with progressive swe...
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Kevin John Karthik Gunasekaran Thomas Alex Kodiatte Ramya Iyyadurai Source Type: research

Fatal aspergillosis of the renal vasculature in a combined liver-kidney transplant recipient
We report a case of 12-year-old female with primary hyperoxaluria with regular haemodialysis for the end-stage renal disease. She underwent a combined liver and renal transplantation which got infected by aspergillosis. In this case study, it is speculated that the most likely source of Aspergillus was contaminated preservative solution (perfusate), resulting in infection within the donor kidney and subsequent systemic infection in the recipient. This case study calls for critical analysis and needs for the routine culture of the preservative solution before transplantation, to detect any fungal contamination and manage it...
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Vasant Nagvekar Chandrasekar H Pranatharthi Ram Gopalakrishnan Ramamurthy Anand Vidya Devarajan Mandayam Thirunarayan Anil Tarigopula Source Type: research

Herpes simplex virus type 2 and cytomegalovirus perigenital ulcer in an HIV infected woman
We report a case of mucocutaneous Herpes Simplex Virus (HSV)-2 and Cytomegalovirus (CMV) infection in a 39-year-old female with acquired immunodeficiency syndrome, who presented with a perigenital ulcer. The patient was receiving antiretroviral treatment (ART) for 3 months before presentation. Scraping from the perigenital ulcer was positive for HSV-2 and Treponema pallidum using polymerase chain reactions (PCR). The extent and duration of the lesions led us to consider the possibility of coinfection with CMV. The patient also tested positive for CMV by PCR. On subsequent follow-up after 8 weeks, the genital lesions had he...
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Jyoti Rawre Mamta Rai Divya Namdeo Rojaleen Das Neena Khanna Lalit Dar Benu Dhawan Source Type: research

Fatal Cryptococcus gattii meningitis with negative cryptococcal antigen test in a HIV-non-infected patient
We report a case of rapidly fatal meningitis by C. gattii in an HIV–non-infected man with CD4 lymphopenia who tested negative for cryptococcal antigen. This case may serve as an alert to its wider occurrence and less explored risk factors. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Vandana Kalwaje Eshwara Rahul Garg G Siddaramappa Chandrashekhar Tushar Shaw Chiranjay Mukhopadhyay Source Type: research

Bioassay and molecular study for detection of insecticide resistance dengue causing mosquito vectors
Monika Soni, Chandrakanta Bhattacharya, Jitendra Sharma, Prafulla DuttaIndian Journal of Medical Microbiology 2018 36(3):435-438Nowadays, dengue infection creates a major problem across the country. The vector species carrying dengue infection has progressively started to developed resistance against most of the currently used insecticides. Hence, a study was carried out in dengue-endemic areas of Assam and Arunachal Pradesh to find the current situation of insecticide susceptibility status of dengue vectors. Based on the previous history of dengue incidence, Aedes mosquitoes were collected from Dibrugarh, Kamrup, Sivasaga...
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Monika Soni Chandrakanta Bhattacharya Jitendra Sharma Prafulla Dutta Source Type: research

Clinical and laboratory characteristics of patients with toxocariasis encountered at a tertiary care centre in North India
This study aims to analyse the clinical and laboratory characteristics of Toxocara-infected patients and assessment of response to standard treatment with review of literature. The clinical details of patients with Toxocara serology positive for IgG antibodies by ELISA in 5 years (2013–2017) were retrospectively analysed. A total of 29 patients with clinical features and serology suggestive of Toxocara infection were evaluated. A complete history of 14 patients was available for the analysis. Majority (13/14; 96.5%) of cases were children <15 years, males (79%) and belonged to ...
Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Jutang Babat Ain Tiewsoh Sumeeta Khurana Abhishek Mewara Rakesh Sehgal Ankita Singh Source Type: research