CD133 Expression Predicts Relapse in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemotherapy
Conclusion: CD133 expression may be a predictive biomarker for postoperative relapse in patients with LARC who received NAC before surgery. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: OI, H., OKUYAMA, T., MIYAZAKI, S., ONO, Y., OYA, M. Tags: Clinical Studies Source Type: research
Evaluation of Sodium (23Na) MR-imaging as a Biomarker and Predictor for Neurodegenerative Changes in Patients With Alzheimers Disease
Conclusion: 23Na-MRI has the potential to be developed as a useful biomarker for the diagnosis of AD. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: MOHAMED, S. A., HERRMANN, K., ADLUNG, A., PASCHKE, N., HAUSNER, L., FRÖLICH, L., SCHAD, L., GRODEN, C., KERL, H. U. Tags: Clinical Studies Source Type: research
A Comparative Study of Pigmented and Non-pigmented Basal Cell Carcinoma in Reflectance Confocal Microscopy
Conclusion: To our knowledge, that is the first study comparing features between pigmented and non-pigmented BCC by RCM. Pigmented and non-pigmented BCCs presented different features in both dermoscopy and RCM. Furthermore, RCM revealed more discriminating features at the DEJ than dermoscopy, thus can be more efficient in the differential diagnosis of difficult BCC. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: POGORZELSKA-ANTKOWIAK, A., GRZEGORCZYN, S., CORNELI, P., SZEPIETOWSKI, J. C. Tags: Clinical Studies Source Type: research
Prognostic Factors After Surgical Treatment of Liver Metastases from Breast Cancer - 19 Years of Experience
Conclusion: The type of surgery had no impact on OS. Markers and hormonal status of liver metastases are important factors affecting prognosis. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: PROCHAZKOVA, K., PIVOVARCIKOVA, K., ROUSAROVA, M., VODICKA, J., HOSEK, P., TRESKOVA, I., HES, O., KUCERA, R., TOPOLCAN, O., TRESKA, V. Tags: Clinical Studies Source Type: research
Comparison of Conventional Fractionation and Accelerated Fractionation With Concomitant Boost for Radiotherapy of Non-metastatic Stage IV Head-and-Neck Cancer
Conclusion: Accelerated fractionation with concomitant boost appeared superior to conventional fractionation and can be considered for patients with stage IV SCCHN not suitable for radiochemotherapy. Larger studies are needed to confirm these findings. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: NARVAEZ, C., SCHILD, S. E., RADES, D. Tags: Clinical Studies Source Type: research
Sarcopenia may Influence the Prognosis in Advanced Thyroid Cancer Patients Treated With Molecular Targeted Therapy
Conclusion: Sarcopenia could be a prognostic factor in patients with advanced thyroid cancer receiving molecular targeted therapy. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: NISHIYAMA, A., STAUB, Y., SUGA, Y., FUJITA, M., TANIMOTO, A., OHTSUBO, K., YANO, S. Tags: Clinical Studies Source Type: research
The Epidemiology, Staging and Outcomes of Sarcomatoid Hepatocellular Carcinoma: A SEER Population Analysis
Conclusion: Sarcomatoid HCC, a rare subtype of HCC, is associated with poor outcomes in terms of overall and disease-specific survival across all disease stages. Surgery seems to be of utmost importance. The eighth edition of the AJCC8 for HCC underperforms in predicting the survival of patients with sarcomatoid subtype. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: GIANNIS, D., MORSY, S., GEROPOULOS, G., ESAGIAN, S. M., SIOUTAS, G. S., MORIS, D. Tags: Clinical Studies Source Type: research
Adolescents and Young Adults (AYAs) With Initially Localized and Metastatic Bone Sarcomas: A Retrospective Single Center Analysis of Side Effect Management
Conclusion: The two studied protocols were well-tolerated in the AYA patients included in this study. Dose reductions instead of dose delays should be considered when side effects occur. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: MINICHSDORFER, C., STEINBRECHER, O., KÖLZ, M., SCHMID, M., RADERER, M., BRODOWICZ, T., LAMM, W. Tags: Clinical Studies Source Type: research
Prognostic Factors in Hormone-sensitive Prostate Cancer Patients Treated With Combined Androgen Blockade: A Consecutive 15-year Study at a Single Japanese Institute
Conclusion: CAB should be considered as a treatment option for strictly selected patients with mHSPC, even though novel treatments are available. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: MIYAZAWA, Y., SEKINE, Y., ARAI, S., OKA, D., NAKAYAMA, H., SYUTO, T., NOMURA, M., KOIKE, H., MATSUI, H., SHIBATA, Y., SUZUKI, K. Tags: Clinical Studies Source Type: research
Predictors for Grip Strength Loss in Patients With Chronic Liver Diseases
Conclusion: Liver functional parameters can be closely linked to the GSL especially in female CLD patients. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: NISHIKAWA, H., YOH, K., ENOMOTO, H., IKEDA, N., TAKASHIMA, T., AIZAWA, N., NISHIMURA, T., NISHIGUCHI, S., IIJIMA, H. Tags: Clinical Studies Source Type: research
Sphenoid Bone Pneumatisation on Lateral Cephalograms of Patients With Neurofibromatosis Type 1
Conclusion: The condition ‘NF1’ has an effect on sphenoid pneumatisation. The findings are relevant for planning surgical procedures in this region and confirm current concepts to evaluate NF1 as a histogenesis control gene. The examination technique and basis of calculation presented here are easy-to-use and low-irradiation exposure instruments for screening for differences in sphenoid bone pneumatisation in defined populations. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: FRIEDRICH, R. E., SCHEUER, H. T., KERSTEN, J. F., SCHEUER, H. A. Tags: Clinical Studies Source Type: research
Metabolic-targeted Combination Therapy With Dichloroacetate and Metformin Suppresses Glioblastoma Cell Line Growth In Vitro and In Vivo
Conclusion: Compounds targeting tumor cell metabolism could become potential treatment options for glioblastoma multiforme. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: KORSAKOVA, L., KRASKO, J. A., STANKEVICIUS, E. Tags: Experimental Studies Source Type: research
Expression of Syndecan-1 in Chronic Liver Diseases: Correlation With Hepatic Fibrosis
Conclusion: In CLDs, syndecan-1 immunohisto-chemical overexpression was found to be positively correlated with the severity of fibrosis, suggesting its probable role in hepatic fibrogenesis. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: CHARCHANTI, A., KANAVAROS, P., KONIARIS, E., KATAKI, A., GLANTZOUNIS, G., AGNANTIS, N. J., GOUSSIA, A. C. Tags: Experimental Studies Source Type: research
Culture Separation, Identification and Unique Anti-pathogenic Fungi Capacity of Endophytic Fungi from Gucheng Salvia Miltiorrhiza
Conclusion: The anti-fungal activities of the endophytic fungus from Salvia miltiorrhiza were confirmed for the first time, and this may benefit crop quality and production in the future. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: WANG, G.-K., YANG, J.-S., HUANG, Y.-F., LIU, J.-S., TSAI, C.-W., BAU, D.-T., CHANG, W.-S. Tags: Experimental Studies Source Type: research
MicroRNA Deregulation in Papillary Thyroid Cancer and its Relationship With BRAF V600E Mutation
Conclusion: Over-expression of selected miRNAs in PTC compared to normal thyroid gland tissue and nodular goitre was found. Moreover, miR-221 may serve as a prognostic marker as its over-expression was significantly associated with recurrent tumors. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: CELAKOVSKY, P., KOVARIKOVA, H., CHROBOK, V., MEJZLIK, J., LACO, J., VOSMIKOVA, H., CHMELAROVA, M., RYSKA, A. Tags: Experimental Studies Source Type: research
