IGF Bioregulation System in Benign and Malignant Thyroid Nodular Disease: A Systematic Review
Conclusion: The present data demonstrate that in most studies there is statistically positive expression of IGF-1 and less of IGF-2 in thyroid cancer compared to normal thyroid tissue. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: KARAGIANNIS, A., KASSI, E., CHATZIGEORGIOU, A., KOUTSILIERIS, M. Tags: Reviews Source Type: research
Follow-up Strategies for Primary Extremity Soft-tissue Sarcoma in Adults: A Systematic Review of the Published Literature
Conclusion: Further research will be needed to establish evidence-based guidelines and schedules for follow-up strategies in patients with eSTS. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: DAMMERER, D., VAN BEECK, A., SCHNEEWEISS, V., SCHWABEGGER, A. Tags: Reviews Source Type: research
Erratum
(Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Tags: Erratum Source Type: research
Lockdown of Breast Cancer Screening for COVID-19: Possible Scenario
Conclusion: Breast cancer screening should be resumed as soon as possible in order to avoid further breast cancer missed diagnosis and reduce the impact of delayed diagnosis. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: VANNI, G., PELLICCIARO, M., MATERAZZO, M., BRUNO, V., OLDANI, C., PISTOLESE, C. A., BUONOMO, C., CASPI, J., GUALTIERI, P., CHIARAVALLOTI, A., PALOMBI, L., PICCIONE, E., BUONOMO, O. C. Tags: Articles on Covid-19 Source Type: research
Preliminary Data of a Quantitative Point of Care Test for SARS-CoV-2 Antibodies From Greece
Conclusion: Using stringent cut-off values, SARS-CoV-2 antibody POCT detects immune people and can be used during socioeconomic normalization of communities. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: FRAGKOU, P. C., PAPAEVANGELOU, V., ANTONIADOU, A., KAVVATHA, D., PLOUSSI, A., PANTAZIS, N., SIRMPILANTZE, T., PSARRAKIS, C., POURNARAS, S. A., TSIODRAS, S., KELEKIS, A. Tags: Articles on Covid-19 Source Type: research
Effect of Lockdown in Surgical Emergency Accesses: Experience of a COVID-19 Hospital
Conclusion: We observed a reduction of surgical emergency accesses during the lockdown. Implementing the use of the regional systems and preventing overcrowding of emergency departments could be beneficial for reducing waiting times and improving the quality of treatments for patients. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: VANNI, G., LEGRAMANTE, J. M., PELLICCIARO, M., DE CAROLIS, G., COTESTA, M., MATERAZZO, M., BUONOMO, C., FARINACCIO, A., SANTORI, F., SARACENO, F., IELPO, B., AIELLO, F., PAGANELLI, C., GRANDE, M., DE ANDREIS, G., CHIOCCHI, M., PALOMBI, L., BUONOMO, O. C. Tags: Articles on Covid-19 Source Type: research
Clinical Study of Hyperglycemia and SARS-CoV-2 Infection in Intensive Care Unit Patients
Conclusion: In our series of ICU patients with SARS-CoV-2 infection, and no history of diabetes, a substantial number of patients had hyperglycemia, to a higher degree than would be expected by the stress of critical illness, lending credence to reports that speculated a tentative association between SARS-CoV-2 and hyperglycemia. This finding is important, since hyperglycemia can lead to further infectious complications. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: ILIAS, I., JAHAJ, E., KOKKORIS, S., ZERVAKIS, D., TEMPERIKIDIS, P., MAGIRA, E., PRATIKAKI, M., VASSILIOU, A. G., ROUTSI, C., KOTANIDOU, A., DIMOPOULOU, I. Tags: Articles on Covid-19 Source Type: research
Raloxifene and Bazedoxifene Could Be Promising Candidates for Preventing the COVID-19 Related Cytokine Storm, ARDS and Mortality
The FDA-approved drugs raloxifene and bazedoxifene could be among the best candidates to prevent mortality in severe COVID-19 patients. Raloxifene and bazedoxifene inhibit IL-6 signaling at therapeutic doses, suggesting they have the potential to prevent the cytokine storm, ARDS and mortality in severe COVID-19 patients, as is being shown with humanized antibodies blocking IL-6 signaling. In addition, raloxifene and bazedoxifene are selective estrogen receptor modulators with strong antiviral activity. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: SMETANA, K., ROSEL, D., BRABEK, J. Tags: Articles on Covid-19 Source Type: research
Ivermectin Docks to the SARS-CoV-2 Spike Receptor-binding Domain Attached to ACE2
Conclusion: The ivermectin docking we identified may interfere with the attachment of the spike to the human cell membrane. Clinical trials now underway should determine whether ivermectin is an effective treatment for SARS-Cov2 infection. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: LEHRER, S., RHEINSTEIN, P. H. Tags: Articles on Covid-19 Source Type: research
Tomato Juice Consumption Could Improve Breast Skin Adverse Effects of Radiotherapy in Breast Cancer Patients
Conclusion: TJ consumption could help in relieving and recovering from early AEs and decreasing the severity of late AEs of irradiated skin. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: FUKUSHI, Y., MARIYA, Y., YAMADA, K., YOSHIDA, K., SASA, A., SAITO, H., HIRAI, A., SUZUKI, S., AIZAWA, K., SUGANUMA, H., ITAKI, C. Tags: Clinical Studies Source Type: research
TGFBI Expression Predicts the Survival of Patients With Oropharyngeal Squamous Cell Carcinoma
Conclusion: High S score of TGFBI was a significant predictor of poor prognosis in OPSCC. TGFBI could be a useful new predictive and prognostic biomarker in OPSCC. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: KIM, H.-J., AHN, D., PARK, T.-I., JEONG, J. Y. Tags: Clinical Studies Source Type: research
Association Between the Efficacy of Pembrolizumab and Low STK11/LKB1 Expression in High-PD-L1-expressing Non-small-cell Lung Cancer
Conclusion: STK11/LKB1 expression, as measured by immunohistochemistry, could be a useful biomarker associated with the efficacy of pembrolizumab monotherapy for patients with NSCLC and a TPS ≥50%. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: HASEGAWA, T., YANAGITANI, N., NINOMIYA, H., SAKAMOTO, H., TOZUKA, T., YOSHIDA, H., AMINO, Y., UEMATSU, S., YOSHIZAWA, T., ARIYASU, R., UCHIBORI, K., KITAZONO, S., HORIIKE, A., NISHIO, M. Tags: Clinical Studies Source Type: research
Stereotactic Body Radiotherapy for Pulmonary Oligometastasis from Colorectal Cancer
Conclusion: Although very high doses were delivered to the tumors with SBRT, the LC of pulmonary metastasis from CRC was not satisfactory when compared to that for stage I primary non-small cell lung cancer reported in the literature. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: KOBAYASHI, N., ABE, T., NODA, S.-E., KUMAZAKI, Y., HIRAI, R., IGARI, M., AOSHIKA, T., SAITO, S., RYUNO, Y., KATO, S. Tags: Clinical Studies Source Type: research
Prognostic Utility of Apical Lymph Node Metastasis in Patients With Left-sided Colorectal Cancer
Conclusion: APN positivity may thus constitute a regional rather than systemic manifestation. The TNM staging based on the number of metastatic lymph nodes seems to be more reasonable than the regional lymph node classification method. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: WANG, L., HIRANO, Y., HENG, G., ISHII, T., KONDO, H., HARA, K., OBARA, N., ASARI, M., YAMAGUCHI, S. Tags: Clinical Studies Source Type: research
Identification of Patients at High Risk for Postsurgical Hypoparathyroidism
Conclusion: PTH postoperative measurement and its alteration from the preoperative level can be used to identify patients who are at increased risk to develop PostHypo. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: KAKAVA, K., TOURNIS, S., MAKRIS, K., PAPADAKIS, G., KASSI, E., DONTAS, I., KARATZAS, T. Tags: Clinical Studies Source Type: research
