Predicting outcome in patients under extracorporeal membrane oxygenation due to cardiogenic shock through dynamic change of lymphocytes and interleukins
Conclusions Combination of the GAM plots and GLM models overcame the complexity of different disease categories. The systemic irreversible damages from cardiogenic shock ECMO cases might be detected from several peripheral blood parameters. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 13, 2014 Category: Endocrinology Source Type: research
Achievement of combined goals of low-density Lipoprotein cholesterol and non-high-density lipoprotein cholesterol with three different statins: Results from VOYAGER
Conclusions Physicians’ choice of statin and dose is important in helping patients achieve the combined LDL-C and non-HDL-C goals recommended in established guidelines. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 13, 2014 Category: Endocrinology Source Type: research
Adaptive servo-ventilation improves exercise oscillatory ventilation and ventilatory inefficiency in patients with heart failure and central sleep apnea
Conclusions ASV improves ventilatory inefficiency and EOV probably via suppression of CSA and its sympathoinhibitory effect. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Systematic review and meta-analysis of remote ischaemic preconditioning in percutaneous coronary intervention
Publication date: December 2013 Source:IJC Metabolic & Endocrine, Volume 1 Author(s): Donagh A. Healy , Patrick J. Carroll , Mary Clarke Moloney , Tjun Y. Tang , Pierce A. Grace , Thomas J. Kiernan , Stewart R. Walsh A body of evidence suggests that myocardial infarctions (MI) that are associated with percutaneous coronary intervention (PCI) have prognostic significance but it is uncertain whether remote ischaemic preconditioning (RIPC) offers periprocedural cardioprotection at the time of PCI. Medline, Embase, the Cochrane Central Register of Controlled Trials and conference records were searched (Janua...
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Effects of ezetimibe on hypercholesterolemia in the lipid profile in patients with metabolic syndrome: Zenith Trial
Conclusions The lipid-lowering effect of ezetimibe in MetS was comparable to that in non-MetS. Treatment with ezetimibe may be effective in males with MetS and relatively lower levels of L/H. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Evaluating the metabolic approach to treatment of diabetic coronary patients
Publication date: December 2013 Source:IJC Metabolic & Endocrine, Volume 1 Author(s): Giuseppe M.C. Rosano , Ilaria Spoletini , Cristiana Vitale , Maurizio Volterrani Diabetic patients with coronary artery disease have an altered myocardial metabolism of glucose and free fatty acids (FFA) and accelerated and diffuse atherogenesis with involvement of peripheral coronary segments that causes chronic hypoperfusion and hibernation. Therefore, in coronary diabetic patients the ischaemic metabolic changes that occur as a consequence of the mismatch between blood supply and cardiac metabolic requirements are heigh...
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
GLP-1R agonists for the prevention of cardiac injury in STEMI patients undergoing PCI: Something new and promising, or not?
Publication date: December 2013 Source:IJC Metabolic & Endocrine, Volume 1 Author(s): Xian Wu Cheng , Toyoaki Murohara , Masafumi Kuzuya The incretin hormone glucagon-like peptide-1 (GLP-1) (7-36)-based therapeutic strategies have been shown to have cardioprotective properties in animal models of ischemia and infarction due to promotion of myocardial glucose uptake and suppression of cardiac cell apoptosis. However, in patient with myocardial infarct, GLP-1 analogues' capacity to effectively protect the heart from dysfunction caused by supply ischemia during percutaneous coronary intervention is still limite...
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Determinants of C-peptide levels and acute insulin resistance/sensitivity in nondiabetic STEMI role of Killip class
Publication date: March 2014 Source:IJC Metabolic & Endocrine, Volume 2 Author(s): Chiara Lazzeri , Serafina Valente , Maria Grazia D'Alfonso , Marco Chiostri , Gian Franco Gensini The alterations in glucose homeostasis in the early phase of nondiabetic ST-elevation myocardial infarction (STEMI) are complex, involving not only hyperglycemia but also the development of acute insulin resistance (as part of the stress response) as assessed by the Homeostatic Model Assessment index (HOMA). No data is so far available on C-peptide values in the acute phase of STEMI in patients without previously known diabetes....
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Impact of ischemic postconditioning with lactate-enriched blood on early inflammation after myocardial infarction
Conclusion PCLeB may suppress early inflammation after MI. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Thirty-day safety and efficacy of prasugrel versus clopidogrel in patients undergoing percutaneous coronary intervention for non-urgent indications and anticoagulated with bivalirudin
Conclusion At 30days, there were no differences in MACE or bleeding complications in patients anticoagulated with bivalirudin and given either clopidogrel or prasugrel during PCI for non-urgent indications. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
The impact of ultrafiltration in acute decompensated heart failure: A systematic review and meta-analysis
Conclusions UF does not appear to reduce mortality, re-hospitalization or unscheduled HF visits in adults with ADHF. At the present time data are insufficient to support routine use of UF for acute HF. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Low-carbohydrate/high-protein diet improves diastolic cardiac function and the metabolic syndrome in overweight-obese patients with type 2 diabetes
Conclusions These data indicate, that a low-glycaemic/high-protein but not a low-fat/high-carbohydrate nutrition modulates diastolic dysfunction in overweight T2D patients, improves insulin resistance and may prevent or delay the onset of diabetic cardiomyopathy and the metabolic syndrome. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Changes in blood pressure classification, blood pressure goals and pharmacological treatment of essential hypertension in medical guidelines from 2003 to 2013
This article aims to discuss differences in pharmacological treatment through a period of 10years from 2003 to 2013. Hypertension treatment faces many challenges because of patients' unawareness and adherence, clinical inertia, as well as rapid availability of new medical literature and trials. Since 2003, JNC 7 was published at nearly the same time with ESC/ESH Guidelines and WHO/ISH Statement on management of hypertension [1–3]. However, these guidelines are not homogenous in pharmacological therapy approach. Moreover, during the 10years since 2003, many new large trials, data, and updated guidelines have resolved some...
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Intensive cardiac rehabilitation improves glucometabolic state of non-diabetic patients with recent coronary artery bypass grafting
Conclusion OGTT is important to evaluate glucometabolic state of CAD patients. Intensive CR improves glucometabolic state and insulin resistance in CAD patients with impaired glucose metabolism. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
Increased epicardial adipose tissue volume predicts insulin resistance and coronary artery disease in non-obese subjects without metabolic syndrome
Conclusion Increased EAT volume may play a key role in the development of insulin resistance and coronary artery disease, even in non-obese subjects without metabolic syndrome. (Source: IJC Metabolic and Endocrine)
Source: IJC Metabolic and Endocrine - November 1, 2014 Category: Endocrinology Source Type: research
