Pattern of dental caries in the historical human population of Kujawy in the Polish lowland (north-central Poland).
Authors: Kurek M, Borowska-Strugińska B, Mazurkiewicz J, Nieczuja-Dwojacka J, Zadzińska E
Abstract
The aim of this study was to determine the dental caries rates in the skeletal human population who lived in north-central Poland in modern times (16th-18th century). The material consisted of 297 skeletons (4,783 permanent teeth) from the archeological site of K. Compared material was coming from two different sites located in the same region: early mediaeval Kolonia--39 skeletons and Swiety Duch (dating to the same historical period as K population)--417 skeletons. All three series are part of the osteolo...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Deciduous tooth growth in an ancient Greek infant cemetery.
Authors: Fitzgerald C, Hillson S
Abstract
The Kylindra cemetery on Astypalaia in the Dodecanese, in use 750 BC to 1st century AD, contains a unique skeletal collection. Over 2,400 infant inhumations, each buried in its own clay pot, have been uncovered so far. The skeletal material from each burial is embedded within a ball of accreted earth and since 2001, some 850 infant remains have been recovered and conserved. Most of these died perinatally, but some were very premature babies and some appear to have survived for several months after birth. A study to estimate ages at death of 277 teeth from 107 infan...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Tooth cementum annulation method: accuracy and applicability.
Authors: Obertová Z, Francken M
Abstract
Tooth cementum annulation (TCA) technique has been a frequently discussed method for the individual age estimation. Conflicting statements on its accuracy and applicability in previous publications have provoked our research. The accuracy and bias of the TCA age estimates were examined in a sample of 116 teeth from 65 individuals of known age and sex from the anatomical collection of the University of Tubingen (Germany). Incremental lines were counted on enhanced digital images of undecalcified, unstained, 60-80 microm thick cross-sections from the middle third of ...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Nothing in nature is as consistent as change.
Authors: Alt KW, Rossbach A
Abstract
Dentition, as a mechanically stressed part of the orofacial system, is subject to physiological wear processes that affect the occlusal surface, the cutting-edge and the approximate contact points of teeth. The reasons are abrasive food particles, tooth contacts during chewing as well as erosion. Up until the Middle ages and even further on, both the deciduous and the permanent dentition were, depending on age, subject to distinct hard tissue defects. These regularly led from normal over-bite, which develops during dentition, to a pronounced edge-to-edge bite. In dentis...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Comparative dental morphology. Preface.
Authors: Koppe T, Meyer G, Alt KW
PMID: 20014504 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Introduction to salivary glands: structure, function and embryonic development.
We describe here where, when and how major salivary glands develop in the lower jaw of the mouse embryo. Key mechanisms involved in this process are discussed, including reciprocal tissue interactions between epithelial and mesenchymal cells, epithelial branching morphogenesis and coordinated cell death and cell proliferation.
PMID: 20428008 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Salivary gland adaptations: modification of the glands for novel uses.
Authors: Tucker AS
Abstract
Salivary glands across the animal kingdom show a huge array of shapes, sizes and variations in number within the oral cavity. Some are branched, others elongated and unbranched, some are small and numerous, while others are greatly enlarged. In most species the salivary glands are used to produce saliva, which lubricates the oral cavity, aids digestion and protects the oral mucosa and dentition. In some species, however, the glands have been modified so that they function in new and diverse ways. Examples include the ability to create thread from the salivary glands to create hi...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Genetic regulation of salivary gland development in Drosophila melanogaster.
Authors: Pirraglia C, Myat MM
Abstract
Studies of salivary gland development in the Drosophila embryo have revealed the morphogenic events by which the salivary gland tubes are formed, and identified the genes and genetic networks that regulate these events. Invagination of the salivary gland primordium occurs by an apical constriction mechanism regulated by the tyrosine kinase, Tec29, the transcription factors, Fork head and Huckebein, and Rho GTPase-mediated actomyosin contraction. After invagination is complete, transcriptional control of the apical membrane protein, Crumbs, by the transcription factors...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Extracellular matrix and growth factors in salivary gland development.
Authors: Sequeira SJ, Larsen M, DeVine T
Abstract
The interstitial extracellular matrix (ECM) and epithelial-cell associated basement membrane (BM) play critical roles in the morphogenesis and differentiation of developing salivary glands. Early studies used ex vivo organ culture and tissue recombination methods to identify the importance of the ECM in organ development. Incorporation of transgenic mice and molecular tools has facilitated progress in our understanding of the mechanisms by which ECM proteins influence SMG development. Recent work has identified alterations in the ECM, BM, and associated pro...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Lumen formation in salivary gland development.
Authors: Wells KL, Patel N
Abstract
During salivary gland morphogenesis, the developing ducts and acini must hollow out to form lumina which will eventually allow the free passage and modification of saliva on its journey from acini to oral cavity. The molecular mechanisms that participate in the creation of this tubular structure are of great research interest. Histological studies show that lumen formation begins during the mid stages of branching morphogenesis. At this stage, apoptotic cells are detectable in the developing salivary ducts at sites where lumina are forming, suggesting that programmed cel...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Epithelial stem/progenitor cells in the embryonic mouse submandibular gland.
Authors: Lombaert IM, Hoffman MP
Abstract
Salivary gland organogenesis involves the specification, maintenance, lineage commitment, and differentiation of epithelial stem/progenitor cells. Identifying how stem/progenitor cells are directed along a series of cell fate decisions to form a functional salivary gland will be necessary for future stem cell regenerative therapy. The identification of stem/progenitor cells within the salivary gland has focused on their role in postnatal glands and little is known about them in embryonic glands. Here, we have reviewed the information available for other developing ...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Salivary gland regeneration.
Authors: Carpenter GH, Cotroneo E
Abstract
The ability of animal salivary glands to recover from an experimentally-induced atrophic state offers hope that human salivary glands may be regenerated following injury. Examination of the mechanisms of regeneration in animal models has revealed processes which resemble the embryonic formation of salivary glands. Secretory proteins present in regenerated acinar and ductal cells are the same as found in the perinatal salivary glands. The use of microarrays to reveal global gene changes has, in combination with bioinformatic techniques, identified some of the impor...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Salivary gland disease.
Authors: Thomas BL, Brown JE, McGurk M
Abstract
Salivary gland disease covers a wide range of pathological entities, including salivary gland-specific disease, as well as manifestations of systemic diseases. This chapter discusses the recent advances in managing obstructive salivary gland disease, the move from gland excision to gland preservation, the dilemmas in diagnosing and managing tumours of the salivary glands, and the international data collection to understand the aetiology and progression of Sjögren's disease.
PMID: 20428015 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Subgingival biofilm structure.
We describe further structural aspects of 'subgingival' biofilms produced in vitro that are gaining considerable interest as we search for models to investigate biofilm development, resistance to antibiotics, extracellular polymeric matrix composition and function, and reciprocal host-cell-to-biofilm interactions.
PMID: 22142954 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
Microbial diversity and interactions in subgingival biofilm communities.
Authors: Diaz PI
Abstract
The human subgingival environment is a complex environmental niche where microorganisms from the three domains of life meet to form diverse biofilm communities that exist in close proximity to the host. Bacteria constitute the most abundant, diverse and ultimately well-studied component of these communities with about 500 bacterial taxa reported to occur in this niche. Cultivation and molecular approaches are revealing the breadth and depth of subgingival biofilm diversity as part of an effort to understand the subgingival microbiome, the collection of microorganisms that inhabit ...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research
