Consequences of X-linked hypohidrotic ectodermal dysplasia for the human jaw bone.
Authors: Lesot H, Clauss F, Manière MC, Schmittbuhl M Abstract Mutations of the Eda gene, which encodes for ectodysplasin-A1, result in X-linked hypohydrotic ectodermal dysplasia (XLHED). This pathology may lead to severe oligodontia, subsequently requiring implant therapy. Since Eda is suspected to participate in bone development, the jaw bone status was investigated in XLHED patients in order to adjust the surgical protocol. Using computed tomography, densitometric profiles and 3D reconstructions, the bone structure was analyzed and compared to that of control individuals; our results showed that the mo...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Dental growth and development: an introduction.
Authors: Kjaer I PMID: 19828978 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Regulation of enamel and dentin mineralization by vitamin D receptor.
CONCLUSION: Vitamin D affects enamel and dentin mineralization through different mechanisms. It may affect the mineralization of dentin systemically while enamel mineralization may be regulated locally. PMID: 19828979 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Patterns of asymmetry in primary tooth emergence of Australian twins.
CONCLUSION: Studies of dental asymmetry provide insights into the biological basis of lateralisation in humans and the results can also assist clinicians to discriminate between normal and abnormal developmental patterns. PMID: 19828980 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Rates of enamel formation in human deciduous teeth.
Authors: Birch W, Dean C Abstract The aim of this study was to document rates of enamel formation in deciduous teeth. Little is known about rates of deciduous enamel formation compared to permanent enamel. In permanent teeth, rates vary between 2.5 microm per day at the EDJ to 6.5 microm per day at the enamel surface. Longitudinal ground sections of twenty mandibular deciduous teeth (4 of each tooth type) made through the crown in the buccolingual plane were selected that showed clearly visible daily enamel cross striations using transmitted polarised light microscopy. Ten average measurements, each one ma...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Tooth root and craniomandibular morphological integration in the common chimpanzee (Pan troglodytes): alternative developmental models for the determinants of root length.
CONCLUSIONS: The findings support previous conclusions that tooth roots demonstrate plasticity during their development. A correlation between root length variation along the tooth row and facial height rather than length can be interpreted in the context of previous findings of maxillary and mandibular rotation and compensatory remodeling during development. It is therefore proposed that the observed root length plasticity is due to variation in the eruptive distance associated with compensatory jaw rotation during development. PMID: 19828982 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Root growth during molar eruption in extant great apes.
Authors: Kelley J, Dean C, Ross S Abstract While there is gradually accumulating knowledge about molar crown formation and the timing of molar eruption in extant great apes, very little is known about root formation during the eruption process. We measured mandibular first and second molar root lengths in extant great ape osteological specimens that died while either the first or second molars were in the process of erupting. For most specimens, teeth were removed so that root lengths could be measured directly. When this was not possible, roots were measured radiographically. We were particularly interest...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Clinical aspects of dental morphology: an introduction.
Authors: Brook A PMID: 19828984 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

How studies of twins can inform our understanding of dental morphology.
Authors: Townsend G, Hughes T, Bockmann M, Smith R, Brook A Abstract Two metaphors are presented to highlight concepts that could lead to a paradigm shift in dental studies of twins. The first, derived from the Song of Solomon in the Bible, refers to teeth as being twins. This viewpoint emphasises that each tooth should be viewed as a paired structure, not only with its antimere (within the same arch) but also with its isomer (in the opposing arch). The other metaphor provided by Waddington in 1957 is visual and involves 'an epigenetic landscape' that represents the processes of decision-making by cells du...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Synetic superimposition of dental 3D data: application in twin studies.
CONCLUSION: Diffusion-based registration offers a more reliable approach to superimposing non-identical objects, such as the tooth crowns of monozygotic co-twins, than conventional best-fit methods. PMID: 19828986 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

A three-dimensional comparison of the modifying effects of familial genetic contribution in Turner syndrome.
Authors: Horrocks LR, Brook A, Alvesalo L, Smith RN Abstract Comparison of individuals affected by chromosomal aneuploidies with controls has already confirmed the differential action of X and Y chromosomes during dental ontogeny. Permanent enamel and dentin structures are formed during the development of the dentition and these reflect the combined effects of both genetic and environmental factors during the prenatal and early postnatal period. It can provide key information on the effect of developmental assaults such as chromosomal aneuploidy as it is not subject to subsequent resorption or remodelling ...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Permanent tooth formation as a method of estimating age.
CONCLUSIONS: These results provide an accurate method to estimate age from developing permanent mandibular teeth. The lack of ethnic difference in dental maturity of individual teeth, suggest that these findings might be appropriate to accurately estimate age for other groups. PMID: 19828988 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Teeth and reconstruction of the past: an introduction.
Authors: Lukacs JR PMID: 19828989 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Can dental caries be interpreted as evidence of farming? The Asian experience.
Authors: Tayles N, Domett K, Halcrow S Abstract The seminal development of control of food production and its social and biological effects on human populations has for a long time been one of the foci of prehistoric research. The relationship between diet and oral pathology is well recognised and accepted to the point where rates of dental caries in particular have been seen as indicative of subsistence mode. This is despite the complex aetiology of caries, with both genetic and environmental factors other than diet contributing to lesion frequency. Most publications considering prehistoric diet and carie...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Teeth and the past in Portugal: pathology and the Mesolithic-Neolithic transition.
Authors: Jackes M Abstract Carious lesions are considered an important marker of dietary change at the transition from hunting and gathering to horticulture. Within the context of the transition to the Neolithic in Central Portugal, this paper discusses factors which must be taken into consideration in reporting dental pathology frequencies. Three sites are examined, two late Mesolithic shell middens and one early Neolithic burial cave dating before 5500 calBP which is taken to b e the end of the transition period. Comparability of results across different burial types and depositional environments require...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research