A Comparison between Osteotomy and Corticotomy-Assisted Tooth Movement.
Authors: Yen SL Abstract Osteotomies and corticotomies used in combination with orthodontic tooth movement can activate different bone responses that may be exploited to accelerate tooth movement. Segmental osteotomies around dental roots can create a tooth-bearing transport disk that may be distracted and positioned with orthodontic appliances and archwires. In difficult craniofacial repairs, alveolar segments can be guided into position with archwires and orthodontic mechanics. The corticotomy extending into the marrow space can activate bone injury repair mechanisms that accelerate bone turnover as the ...
Source: Frontiers of Oral Biology - November 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Conclusion and Future Directions.
Authors: Kantarci A, Yen S, Will LA PMID: 26599127 [PubMed - in process] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Preface.
Authors: Deb S PMID: 26470407 [PubMed - in process] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - October 18, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Biomaterials in Relation to Dentistry.
Authors: Deb S, Chana S Abstract Dental caries remains a challenge in the improvement of oral health. It is the most common and widespread biofilm-dependent oral disease, resulting in the destruction of tooth structure by the acidic attack from cariogenic bacteria. The tooth is a heavily mineralised tissue, and both enamel and dentine can undergo demineralisation due to trauma or dietary conditions. The adult population worldwide affected by dental caries is enormous and despite significant advances in caries prevention and tooth restoration, treatments continue to pose a substantial burden to healthcare. ...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Polymer Therapeutics in Relation to Dentistry.
Authors: Rojo L, Deb S Abstract The successful clinical application arising from advances in polymer and macromolecular sciences in different fields of medicine has opened new explorative approaches for the future design and development of the ever more sophisticated bio-/nanotechnologies that are needed to realise the full potential of modern dentistry. In this chapter, the most recent polymer therapeutic approaches for alveolar ridge augmentation, bone grafts, periodontal disease, restorative materials and scaffolds or carriers for cell-based therapies are presented highlighting the potential of either s...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Biological Impact of Bioactive Glasses and Their Dissolution Products.
Authors: Hoppe A, Boccaccini AR Abstract For many years, bioactive glasses (BGs) have been widely considered for bone tissue engineering applications due to their ability to bond to hard as well as soft tissue (a property termed bioactivity) and for their stimulating effects on bone formation. Ionic dissolution products released during the degradation of the BG matrix induce osteogenic gene expression leading to enhanced bone regeneration. Recently, adding bioactive metallic ions (e.g. boron, copper, cobalt, silver, zinc and strontium) to silicate (or phosphate and borate) glasses has emerged as a promisin...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Organic-Inorganic Composites Toward Biomaterial Application.
Authors: Miyazaki T, Sugawara-Narutaki A, Ohtsuki C Abstract Bioactive ceramics are known to exhibit specific biological affinities and are able to show direct integration with surrounding bone when implanted in bony defects. However, their inadequate mechanical properties, such as low fracture toughness and high Young's modulus in comparison to natural bone, limit their clinical application. Bone is a kind of organic-inorganic composite where apatite nanocrystals are precipitated onto collagen fibre networks. Thus, one way to address these problems is to mimic the natural composition of bone by using bioa...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

New Advanced Materials for High Performance at the Resin-Dentine Interface.
Authors: Toledano M, Osorio R Abstract This chapter provides a tool for the integration of new concepts and biomaterials related with the resin-dentine interface. The principles of dentine demineralisation and remineralisation that shape modern restorative dentistry practices, as well as considerations for the selection of new materials for different restorative approaches, are emphasised. Re-incorporation of mineral into the demineralised dentine matrix is important since the mineral precipitated may work as a constant site for further nucleation, and the remineralised subsurface of the tissue may be more...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Nanobiomaterial Coatings in Dentistry.
Authors: Choi AH, Cazalbou S, Ben-Nissan B Abstract During the last decade, there has been a major increase in the interest of nanostructured materials in advanced technologies for biomedical and dental clinical applications. Nanostructured materials are associated with a variety of applications within the dental and biomedical field, for example nanoparticles in drug delivery systems and nanostructured scaffolds in tissue engineering. More importantly, nanotechnology has also been linked with the modification of surface properties of synthetic implants in an attempt to improve their bioactivity, reliabili...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

The Effect of Titanium Surface Modifications on Dental Implant Osseointegration.
Authors: Annunziata M, Guida L Abstract The use of titanium dental implants has consistently changed the way of rehabilitating patients in modern dentistry and can count on high long-term survival and success rates. With respect to its introduction in the late 1960s, clinical indications for implant therapy have been significantly extended and optimal results have been achieved, even in clinical conditions formerly considered as unfavourable. Such evolution owes a lot to the significant progress made in the field of titanium surfaces. The topographical and chemical modification of traditional titanium surf...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Global Gene Expression Analysis for the Assessment of Nanobiomaterials.
Authors: Hanagata N Abstract Using global gene expression analysis, the effects of biomaterials and nanomaterials can be analyzed at the genetic level. Even though information obtained from global gene expression analysis can be useful for the evaluation and design of biomaterials and nanomaterials, its use for these purposes is not widespread. This is due to the difficulties involved in data analysis. Because the expression data of about 20,000 genes can be obtained at once with global gene expression analysis, the data must be analyzed using bioinformatics. A method of bioinformatic analysis called gene ...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Membranes for Periodontal Regeneration - A Materials Perspective.
Authors: Bottino MC, Thomas V Abstract Periodontitis is a chronic inflammatory disorder affecting nearly 50% of adults in the United States. If left untreated, it can lead to the destruction of both soft and mineralized tissues that constitute the periodontium. Clinical management, including but not limited to flap debridement and/or curettage, as well as regenerative-based strategies with periodontal membranes associated or not with grafting materials, has been used with distinct levels of success. Unquestionably, no single implantable biomaterial can consistently guide the coordinated growth and developm...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Biomaterials in the Reconstruction of the Oral and Maxillofacial Region.
Authors: Ayoub A, Al-Fotawei R Abstract Reconstruction of maxillofacial bones has proven to be complex due to the aesthetic requirements and functional demands of the jaw. Although autogenous bone grafts and a wide range of biomaterials are routinely used for facial bone reconstruction, these methods are associated with a number of drawbacks, including the limited availability of autogenous grafts and the morbidity associated with bone graft harvesting, whilst biomaterials are also linked with a high failure rate. These limitations have inspired the search for innovative techniques for bone bioengineering ...
Source: Frontiers of Oral Biology - July 26, 2015 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Developmental anatomy of craniofacial sutures.
Authors: Rice DP Abstract Sutures are fibrous joints in the vertebrate skull. They consist of two bone ends and intervening fibrous tissue which differentiates from embryonic mesenchyme. Sutures are not merely articulations between bones they are primary sites of osteogenesis mediating much of the growth of the face and skull vault. In this chapter the development of sutures will be described including the origin of sutural tissues, the determinants of suture location, and suture morphology. Also, the main functions of sutures will be explained. PMID: 18391492 [PubMed - indexed for MEDLINE] (Source...
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research

Locate, condense, differentiate, grow and confront: developmental mechanisms controlling intramembranous bone and suture formation and function.
Authors: Rice DP, Rice R Abstract The key mechanisms controlling where and when craniofacial bones and hence sutures form are discussed in this review. These include the formation and growth of skeletogenic condensations, tissue to tissue interactions between the epithelium, skeletogenic mesenchyme and the underlying dural and neural tissues. Also discussed are the key processes determining intramembranous bone growth, namely osteoblastogenesis and osteoclastogenesis. PMID: 18391493 [PubMed - indexed for MEDLINE] (Source: Frontiers of Oral Biology)
Source: Frontiers of Oral Biology - November 25, 2014 Category: ENT & OMF Tags: Front Oral Biol Source Type: research