A real world study on the genetic, cognitive and psychopathological differences of obese patients clustered according to eating behaviours
Conclusions Aside from binge eating, dysfunctional eating behaviours were useful symptoms to identify two different phenotypes of obese patients from a comprehensive set of parameters (genetic, clinical, personality and neuropsychology) in this sample. Grazing and emotional eating were the most important predictors for classifying obese patients, followed by binge eating. This clustering overcomes the idea that ‘binging’ is the predominant altered eating behaviour, and could help physicians other than psychiatrists to identify whether an obese patient has an eating disorder. Finally, recognising different types of obes...
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Long-term reduction of seclusion and forced medication on a hospital-wide level: Implementation of an open-door policy over 6 years
Conclusion This underlines the potential of the introduction of an open-door policy to attain a long-term reduction in involuntary measures. (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Commentary on “Motor system dysfunction in the schizophrenia diathesis: Neural systems to neurotransmitters”
Publication date: February 2018 Source:European Psychiatry, Volume 48 Author(s): D. Hirjak, P.N. van Harten, R.C. Wolf (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Variation of genes involved in oxidative and nitrosative stresses in depression
In this study, we examined the association between single-nucleotide polymorphisms of the genes encoding SOD2 (superoxide dismutase 2), CAT (catalase), GPx4 (glutathione peroxidase 4), NOS1 (nitric oxide synthase 1), NOS2 (nitric oxide synthase 2), and the development of depressive disorders. Our study was carried out on the DNA isolated from peripheral blood collected from 281 depressed patients and 229 controls. Using TaqMan probes, we genotyped the following six polymorphisms: c.47T>C (p.Val16Ala) (rs4880) in SOD2, c.-89A>T (rs7943316) in CAT, c.660T>C (rs713041) in GPx4, c.-420-34221G>A (rs1...
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Problem-solving therapy for adult depression: An updated meta-analysis
Conclusion PST is probably an effective treatment for depression, with effect sizes that are small, but comparable to those found for other psychological treatments of depression. (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

The interaction between neurocognitive functioning, subthreshold psychotic symptoms and pharmacotherapy in 22q11.2 deletion syndrome: A longitudinal comparative study
Conclusions Our results highlight the time-dependent interplay among positive and negative SPS symptoms, neurocognition and pharmacotherapy in the prediction of the evolution of psychosis in 22q11DS. (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Effects of physical activity on the symptoms of Tourette syndrome: A systematic review
Publication date: February 2018 Source:European Psychiatry, Volume 48 Author(s): David D. Kim, Darren E.R. Warburton, Nana Wu, Alasdair M. Barr, William G. Honer, Ric M. Procyshyn There is irrefutable evidence that routine physical activity or exercise can offer considerable health benefits to individuals living with various mental disorders. However, it is not clear what effect physical activity has on the symptoms of Tourette syndrome. Despite a paucity of evidence, physical activity or exercise has already been recommended by various health organizations for the management of tics. We provide a systematic review...
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Predictors of length of stay in psychiatric inpatient units: Does their effect vary across countries?
Conclusions The same patient characteristics have a different impact on LoS in different contexts. Thus, although some predictor variables related to clinical severity and social dysfunction appear of generalisable relevance, national studies on LoS are required to understand the complex influence of different patient characteristics on clinical practice in the given contexts. (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Latent class analysis of the health of the nation outcome scales: A comparison of Swiss and English profiles and exploration of their predictive utility
Publication date: February 2018 Source:European Psychiatry, Volume 48 Author(s): P. Maddison, P. Golay, S.J. Muncer (Source: European Psychiatry)
Source: European Psychiatry - January 12, 2018 Category: Psychiatry Source Type: research

Healthy minds from 0 –100 years: Optimising the use of European brain imaging cohorts (“Lifebrain”)
Publication date: January 2018 Source:European Psychiatry, Volume 47 Author(s): K.B. Walhovd, A.M. Fjell, R. Westerhausen, L. Nyberg, K.P. Ebmeier, U. Lindenberger, D. Bartrés-Faz, W.F.C. Baaré, H.R. Siebner, R. Henson, C.A. Drevon, G.P. Knudsen, I. Budin-Ljøsne, B.W.J.H. Penninx, P. Ghisletta, O. Rogeberg, L. Tyler, L. Bertram The main objective of “Lifebrain” is to identify the determinants of brain, cognitive and mental (BCM) health at different stages of life. By integrating, harmonising and enriching major European neuroimaging studies across the life span, we will merge fine-grained BCM hea...
Source: European Psychiatry - November 9, 2017 Category: Psychiatry Source Type: research

Satisfaction of psychotic patients with care and its value to predict outcomes
Conclusions Satisfaction of patients with psychosis is a valuable monitoring measure since high satisfied patients show more favorable outcomes ranging from psychopathological symptoms to quality of life. Further research into explanations of lower levels of satisfaction is commendable in order to improve outcomes. (Source: European Psychiatry)
Source: European Psychiatry - November 3, 2017 Category: Psychiatry Source Type: research

Response to commentary by Li et al
Publication date: January 2018 Source:European Psychiatry, Volume 47 Author(s): S. Andalib, M.S. Vafaee, T.M. Michel (Source: European Psychiatry)
Source: European Psychiatry - November 3, 2017 Category: Psychiatry Source Type: research

Regulation of inflammatory pathways in schizophrenia: A comparative study with bipolar disorder and healthy controls
Conclusions This study suggests a specific immune-inflammatory biomarker pattern for established SCH (NFκB, PGE2, iNOS, and COX-2) that differentiates it from BD and HC. In future, their pharmacological modulation may constitute a promising therapeutic target. (Source: European Psychiatry)
Source: European Psychiatry - October 29, 2017 Category: Psychiatry Source Type: research

The danger of being inattentive  – ADHD symptoms and risky sexual behaviour in Russian adolescents
Conclusions Deficits in planning and organizing behaviours, being easily distracted and forgetful seem to be of importance for RSB in Russian adolescents. This highlights the importance of discriminating between different types of ADHD symptoms in adolescence to prevent risk behaviours and their potentially detrimental outcomes on health and well-being. (Source: European Psychiatry)
Source: European Psychiatry - September 29, 2017 Category: Psychiatry Source Type: research

Are comorbid anxiety disorders a risk factor for suicide attempts in patients with mood disorders? A two-year prospective study
Conclusions Our results suggest that comorbid anxiety disorders were not risk factors for suicide attempts. Further studies were needed to determine the role of anxiety disorders as risk factors for suicide attempts. (Source: European Psychiatry)
Source: European Psychiatry - September 29, 2017 Category: Psychiatry Source Type: research