Angiotensin 1 ‐7 Modulates Electrophysiological Characteristics and Calcium Homeostasis in Pulmonary Veins Cardiomyocytes via Mas/PI3K/eNOS signaling pathway
ConclusionAng‐(1‐7) regulates PV electrophysiological characteristics and Ca2+ homeostasis via Mas/PI3K/eNOS signaling pathway.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - November 1, 2017 Category: General Medicine Authors: Yen ‐Yu Lu, Wen‐Shiann Wu, Yung‐Kuo Lin, Chen‐Chuan Cheng, Yao‐Chang Chen, Shih‐Ann Chen, Yi‐Jen Chen Tags: Original Article Source Type: research

Oedema ‐fibrosis in Duchenne Muscular Dystrophy: Role of cardiovascular magnetic resonance imaging
Abstract Duchenne muscular dystrophy (DMD) is an X‐linked muscle disorder characterized by progressive, irreversible loss of cardiac and skeletal muscular function. Muscular enlargement in DMD is attributed to oedema, due to the increased cytoplasmic Na+ concentration. The aim of this review was to present the current experience and emphasize the role of cardiovascular magnetic resonance (CMR) in the diagnosis of this condition. DMD patients' survival depends on ventilatory assistance, as respiratory muscle dysfunction was the most common cause of death in the past. Currently, due to improved ventilatory assistance, card...
Source: European Journal of Clinical Investigation - October 31, 2017 Category: General Medicine Authors: Sophie Mavrogeni, Antigoni Papavasiliou, Katerina Giannakopoulou, George Markousis ‐Mavrogenis, Maria Roser Pons, Evangelos Karanasios, Ioannis Nikas, George Papadopoulos, Genovefa Kolovou, George P. Chrousos Tags: REVIEW Source Type: research

Dynamics of neutrophil gelatinase ‐associated lipocalin plasma and cerebrospinal fluid concentrations in older males
ConclusionsThis study illustrates the temporal regulation of NGAL in plasma and CSF, which potentially is a useful reference for studies measuring NGAL as biomarker in older individuals.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - October 30, 2017 Category: General Medicine Authors: Petrus J.W. Naud é, Doortje W. Dekens, Ulrich L.M. Eisel, Izaak den Daas, Peter P. De Deyn Tags: Original Paper Source Type: research

Cardiopulmonary exercise test predicts right heart catheterization
ConclusionIn patients with suspected PAH, VEint during exercise and the VE/VCO2 slope might provide useful information to predict results of RHC. Their correlations with PVR and with DPG may be helpful in discriminating patients with isolated post‐capillary PH from those with combined post‐capillary and pre‐capillary.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - October 30, 2017 Category: General Medicine Authors: Michele Correale, Lucia Tricarico, Armando Ferraretti, Ilenia Monaco, Morena Concilio, Giuseppina Padovano, Gianfranco Acanfora, Matteo Di Biase, Natale Daniele Brunetti Tags: Original Paper Source Type: research

Ventricular Mechanics After Repair of Subarterial and Perimembranous VSDs
ConclusionAdolescents and adults late after repair of subarterial and perimembranous VSDs show impairment of RV systolic and diastolic myocardial deformation. The RV outflow function and LV systolic deformation appear to be worse after repair of subarterial defects.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - October 30, 2017 Category: General Medicine Authors: Sit ‐yee Kwok, Susanna So‐shan Yeung, Vivian Wing‐yi Li, Yiu‐fai Cheung Tags: Original Paper Source Type: research