The Molecular Registry of Pituitary Adenomas (REMAH): A bet by Spanish Endocrinology for the future of individualized medicine and translational research
Publication date: Available online 14 July 2016 Source:Endocrinología y Nutrición (English Edition) Author(s): Raúl M. Luque, Alejandro Ibáñez-Costa, Laura Sánchez-Tejada, Esther Rivero-Cortés, Mercedes Robledo, Ainara Madrazo-Atutxa, Mireia Mora, Clara V. Álvarez, Tomás Lucas-Morante, Cristina Álvarez-Escolá, Carmen Fajardo, Luis Castaño, Sonia Gaztambide, Eva Venegas-Moreno, Alfonso Soto-Moreno, María Ángeles Gálvez, Javier Salvador, Elena Valassi, Susan M. Webb, Antonio Picó, Manel Puig-Domingo, Montserrat Gilabert, Ignacio Bernabéu, Mónica Marazuela,...
Source: Endocrinologia y Nutricion - July 15, 2016 Category: Endocrinology Source Type: research
Complete pituitary infarction associated with hypothermia and brain death
Publication date: May 2016 Source:Endocrinología y Nutrición (English Edition), Volume 63, Issue 5 Author(s): Run Yu, Xuemo Fan, Serguei I. Bannykh (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - June 9, 2016 Category: Endocrinology Source Type: research
Statin-related myotoxicity
Publication date: May 2016 Source:Endocrinología y Nutrición (English Edition), Volume 63, Issue 5 Author(s): Vera Fernandes, Maria Joana Santos, Antonio Pérez Statin therapy has a very important role in decreasing cardiovascular risk, and treatment non-compliance may therefore be a concern in high cardiovascular risk patients. Myotoxicity is a frequent side effect of statin therapy and one of the main causes of statin discontinuation, which limits effective treatment of patients at risk of or with cardiovascular disease. Because of the high proportion of patients on statin treatment and the frequency of stati...
Source: Endocrinologia y Nutricion - June 9, 2016 Category: Endocrinology Source Type: research
Diagnosis and treatment of hyponatraemia in neurosurgical patients
Publication date: May 2016 Source:Endocrinología y Nutrición (English Edition), Volume 63, Issue 5 Author(s): Martín Cuesta, Mark J. Hannon, Christopher J. Thompson Hyponatraemia is the most common electrolyte imbalance in neurosurgical patients. Acute hyponatraemia is particularly common in neurosurgical patients after any type of brain insult, including brain tumours and their treatment, pituitary surgery, subarachnoid haemorrhage or traumatic brain injury. Acute hyponatraemia is an emergency condition, as it leads to cerebral oedema due to passive osmotic movement of water from the hypotonic plasma to the r...
Source: Endocrinologia y Nutricion - June 9, 2016 Category: Endocrinology Source Type: research
Adrenocortical carcinoma: Retrospective analysis of the last 22 years
Conclusion Despite the overall poor prognosis, some patients with ACC may have a long survival time. Although complete tumor removal remains the only potentially curative treatment, diagnosis at a younger age, presence of non-functioning tumors, and mitotane treatment also seemed to be associated to longer survival in our patients. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - June 9, 2016 Category: Endocrinology Source Type: research
Sex steroids and growth hormone interactions
Publication date: April 2016 Source:Endocrinología y Nutrición (English Edition), Volume 63, Issue 4 Author(s): Leandro Fernández-Pérez, Mercedes de Mirecki-Garrido, Borja Guerra, Mario Díaz, Juan Carlos Díaz-Chico GH and sex hormones are critical regulators of body growth and composition, somatic development, intermediate metabolism, and sexual dimorphism. Deficiencies in GH- or sex hormone-dependent signaling and the influence of sex hormones on GH biology may have a dramatic impact on liver physiology during somatic development and in adulthood. Effects of sex hormones on the liver may be direct, thr...
Source: Endocrinologia y Nutricion - May 30, 2016 Category: Endocrinology Source Type: research
Spanish consensus for the management of patients with advanced radioactive iodine refractory differentiated thyroid cancer
Conclusions In response to our appointment as a task force by the SEEN and GHETI, we developed a consensus to help in clinical management of patients with advanced RAI-refractory DTC. We think that this consensus will provide helpful and current recommendations that will help patients with this disorder to get optimal medical care. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 30, 2016 Category: Endocrinology Source Type: research
Prevalence of impaired fasting glucose and type 1 and 2 diabetes mellitus in a large nationwide working population in Spain
Discussion In this sample of Spanish working population, impaired glycemic profiles were common. Prevalence rates of IFG and T2DM were high among blue-collar workers (except for T1DM). These data emphasize the need for earlier structured preventive schemes. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 30, 2016 Category: Endocrinology Source Type: research
Association between information sources and level of knowledge about diabetes in patients with type 2 diabetes
Conclusion Search for information in the Internet was positively associated to a good level of knowledge. It is suggested to teach patients with diabetes to seek information on the Internet and, on the other hand, to develop virtual spaces for interaction of patients with diabetes. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 27, 2016 Category: Endocrinology Source Type: research
Hiperglycemic hyperosmolar state: An unsual way of first appearance of type 1 diabetes in children
Publication date: Available online 27 May 2016 Source:Endocrinología y Nutrición (English Edition) Author(s): Ana Hernández Moreno, María Sanz Fernández, María D. Ballesteros Pomar, Amparo Rodríguez Sánchez (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 27, 2016 Category: Endocrinology Source Type: research
Physical performance and muscle strength in older patients with and without diabetes from a public hospital in Lima, Peru
Conclusions No association was found between T2DM, MS, and PP. However, low PP was associated to female sex and overweight/obesity, and decreased MS was associated to high body fat percentage and underweight. Moreover, MS and PP were related to older age and history of hospitalization. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 27, 2016 Category: Endocrinology Source Type: research
Effect of incretin therapies compared to pioglitazone and gliclazide in non-alcoholic fatty liver disease in diabetic patients not controlled on metformin alone: An observational, pilot study
Conclusions Qualitative ultrasonographic NAFLD improvement in diabetic patients treated with metformin in combination with other hypoglycemic drugs is associated to change over time in weight and waist circumference. Long-term clinical trials are needed to assess whether incretin therapies result in better liver outcomes than other hypoglycemic therapies. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 26, 2016 Category: Endocrinology Source Type: research
Diabetes mellitus and Alzheimer's disease: An unforgettable relation
Publication date: Available online 26 May 2016 Source:Endocrinología y Nutrición (English Edition) Author(s): Andreea Ciudin (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - May 25, 2016 Category: Endocrinology Source Type: research
Effective adverse event reduction with bolus-basal versus sliding scale insulin therapy in patients with diabetes during conventional hospitalization: Systematic review and meta-analysis
Conclusion Despite its benefit for glycemic control during hospitalization, this review did not show that use of the BB scheme decreases clinical events in patients hospitalized in a conventional ward. Because of heterogeneity of the results, we think that clinical trials are needed addressing its effect in patient subgroups in which the BB scheme may be used safely and with longer follow-up periods. (Source: Endocrinologia y Nutricion)
Source: Endocrinologia y Nutricion - April 24, 2016 Category: Endocrinology Source Type: research
Tumour-induced osteomalacia: An emergent paraneoplastic syndrome
Publication date: Available online 23 April 2016 Source:Endocrinología y Nutrición (English Edition) Author(s): Guillermo Alonso, Mariela Varsavsky Endocrine paraneoplastic syndromes are distant manifestations of some tumours. An uncommon but increasingly reported form is tumour-induced osteomalacia, a hypophosphatemic disorder associated to fibroblast growth factor 23 (FGF-23) secretion by tumours. The main biochemical manifestations of this disorder include hypophosphatemia, inappropriately low or normal tubular reabsorption of phosphate, low serum calcitriol levels, increased serum alkaline phosphatase levels,...
Source: Endocrinologia y Nutricion - April 22, 2016 Category: Endocrinology Source Type: research
