---
Clinical and Translational Science, Ahead of Print. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - December 1, 2017 Category: Biomedical Science Source Type: research
Diagnostic Testing for Zika: Observing Rapid Translation During a Public Health Emergency
(Source: Clinical and Translational Science)
Source: Clinical and Translational Science - December 1, 2017 Category: Biomedical Science Authors: Shaheen Kurani, Elitza Theel, Alexandra Greenberg ‐Worisek Tags: COMMENTARY Source Type: research
Translational Development of Microbiome ‐Based Therapeutics: Kinetics of E. coli Nissle and Engineered Strains in Humans and Nonhuman Primates
Abstract
Understanding the pharmacology of microbiome‐based therapeutics is required to support the development of new medicines. Strains of E. coli Nissle (EcN) were genetically modified and administered to cynomolgus monkeys at doses of 1 × 109 and 1 × 1012 colony‐forming units (CFU)/day for 28 days. A clinical study to evaluate the exposure and clearance of EcN in healthy volunteers was also performed. Healthy subjects received oral doses of EcN, 2.5 to 25 × 109 CFU 3 times daily for 28 days or a single day. In cynomolgus monkeys, replicating strains yielded higher fecal concentrations than nonreplicating strain...
Source: Clinical and Translational Science - December 1, 2017 Category: Biomedical Science Authors: Caroline Kurtz, William S. Denney, Larry Blankstein, Sarah E. Guilmain, Suman Machinani, Jonathan Kotula, Saurabh Saha, Paul Miller, Aoife M. Brennan Tags: ARTICLE Source Type: research
Teaching Targeted Drug Discovery and Development to Healthcare Professionals
Clinical and Translational Science, EarlyView. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Inflammatory and Physiological Consequences of Debridement of Fibrous Tissue after Volumetric Muscle Loss Injury
Clinical and Translational Science,Volume 11, Issue 2, Page 208-217, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources
Clinical and Translational Science,Volume 11, Issue 2, Page 106-108, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years
Clinical and Translational Science,Volume 11, Issue 2, Page 189-199, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Teaching Targeted Drug Discovery and Development to Healthcare Professionals
Clinical and Translational Science, EarlyView. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Inflammatory and Physiological Consequences of Debridement of Fibrous Tissue after Volumetric Muscle Loss Injury
Clinical and Translational Science,Volume 11, Issue 2, Page 208-217, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Reverse Translation in Advancing Pharmacotherapy in Pediatric Rheumatology: A Logical Approach in Rare Diseases with Limited Resources
Clinical and Translational Science,Volume 11, Issue 2, Page 106-108, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
Clinical Implementation of Pharmacogenetic Testing in a Hospital of the Spanish National Health System: Strategy and Experience Over 3 Years
Clinical and Translational Science,Volume 11, Issue 2, Page 189-199, March 2018. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
---
Clinical and Translational Science, Ahead of Print. (Source: Clinical and Translational Science)
Source: Clinical and Translational Science - November 28, 2017 Category: Biomedical Science Source Type: research
