Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade
Publication date: Available online 24 December 2020Source: Cancer CellAuthor(s): Shivani Srivastava, Scott N. Furlan, Carla A. Jaeger-Ruckstuhl, Megha Sarvothama, Carolina Berger, Kimberly S. Smythe, Sarah M. Garrison, Jennifer M. Specht, Sylvia M. Lee, Robert A. Amezquita, Valentin Voillet, Vishaka Muhunthan, Sushma Yechan-Gunja, Smitha P.S. Pillai, Christoph Rader, A. McGarry Houghton, Robert H. Pierce, Raphael Gottardo, David G. Maloney, Stanley R. Riddell (Source: Cancer Cell)
Source: Cancer Cell - December 25, 2020 Category: Cancer & Oncology Source Type: research

Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site
Publication date: Available online 24 December 2020Source: Cancer CellAuthor(s): Shuo Chen, Jia-Le Wu, Ying Liang, Yi-Gang Tang, Hua-Xin Song, Li-Li Wu, Yang-Fei Xing, Ni Yan, Yun-Tong Li, Zheng-Yuan Wang, Shu-Jun Xiao, Xin Lu, Sai-Juan Chen, Min Lu (Source: Cancer Cell)
Source: Cancer Cell - December 25, 2020 Category: Cancer & Oncology Source Type: research

The Jekyll and Hyde of Senescence in Cancer: TIMP1 Controls the Switch from Tumor-Controlling to Tumor-Promoting Senescence
Publication date: Available online 24 December 2020Source: Cancer CellAuthor(s): Sabela Da Silva-Álvarez, Manuel Collado (Source: Cancer Cell)
Source: Cancer Cell - December 25, 2020 Category: Cancer & Oncology Source Type: research

Immunomodulation by targeted anticancer agents
Publication date: Available online 17 December 2020Source: Cancer CellAuthor(s): Giulia Petroni, Aitziber Buqué, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi (Source: Cancer Cell)
Source: Cancer Cell - December 18, 2020 Category: Cancer & Oncology Source Type: research

DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
Publication date: Available online 17 December 2020Source: Cancer CellAuthor(s): Changzheng Lu, Junhong Guan, Steve Lu, Qihuang Jin, Benoit Rousseau, Tianshi Lu, Dennis Stephens, Hongyi Zhang, Jiankun Zhu, Mingming Yang, Zhenhua Ren, Yong Liang, Zhida Liu, Chuanhui Han, Longchao Liu, Xuezhi Cao, Anli Zhang, Jian Qiao, Kimberly Batten, Mingyi Chen (Source: Cancer Cell)
Source: Cancer Cell - December 18, 2020 Category: Cancer & Oncology Source Type: research

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
Publication date: Available online 17 December 2020Source: Cancer CellAuthor(s): Junhong Guan, Changzheng Lu, Qihuang Jin, Huiming Lu, Xiang Chen, Lei Tian, Yanbin Zhang, Janice Ortega, Junqiu Zhang, Silvia Siteni, Mingyi Chen, Liya Gu, Jerry W. Shay, Anthony J. Davis, Zhijian J. Chen, Yang-Xin Fu, Guo-Min Li (Source: Cancer Cell)
Source: Cancer Cell - December 18, 2020 Category: Cancer & Oncology Source Type: research

Angelika Amon (1967–2020)
Publication date: 14 December 2020Source: Cancer Cell, Volume 38, Issue 6Author(s): Charles Swanton (Source: Cancer Cell)
Source: Cancer Cell - December 15, 2020 Category: Cancer & Oncology Source Type: research

Utility of Preoperative Computed Tomography Scans for Coronavirus Disease in a Cancer Treatment Center
Publication date: Available online 10 December 2020Source: Cancer CellAuthor(s): Yukinori Ozaki, Jun Masuda, Akemi Kataoka, Katsunori Oikado, Natsue Uehiro, Lina Inagaki, Chieko Kato, Hidetomo Morizono, Toshimi Takano, Takayuki Ueno, Shinji Ohno (Source: Cancer Cell)
Source: Cancer Cell - December 12, 2020 Category: Cancer & Oncology Source Type: research

Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma
Publication date: Available online 10 December 2020Source: Cancer CellAuthor(s): Catherine S. Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y. Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie Campbell, Agustin Vega-Crespo, Michael Quist, Christophe Martignier, Jason J. Luke, Jedd D. Wolchok, Douglas B. Johnson (Source: Cancer Cell)
Source: Cancer Cell - December 12, 2020 Category: Cancer & Oncology Source Type: research

Normal Somatic Mutations in Cancer Transformation
Publication date: Available online 20 November 2020Source: Cancer CellAuthor(s): Neshika Wijewardhane, Lisa Dressler, Francesca D. Ciccarelli (Source: Cancer Cell)
Source: Cancer Cell - November 21, 2020 Category: Cancer & Oncology Source Type: research

Takashi Sugimura (1926–2020)
Publication date: Available online 19 November 2020Source: Cancer CellAuthor(s): Curtis C. Harris, Ze’ev A. Ronai (Source: Cancer Cell)
Source: Cancer Cell - November 20, 2020 Category: Cancer & Oncology Source Type: research

Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment
Publication date: Available online 19 November 2020Source: Cancer CellAuthor(s): David A. Wheeler, Naoko Takebe, Toshinori Hinoue, Katherine A. Hoadley, Maria F. Cardenas, Alina M. Hamilton, Peter W. Laird, Linghua Wang, Adrienne Johnson, Ninad Dewal, Vincent Miller, David Piñeyro, Manuel Castro de Moura, Manel Esteller, Hui Shen, Jean Claude Zenklusen, Roy Tarnuzzer, Lisa M. McShane, James V. Tricoli, Paul M. Williams (Source: Cancer Cell)
Source: Cancer Cell - November 20, 2020 Category: Cancer & Oncology Source Type: research

Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
Publication date: Available online 19 November 2020Source: Cancer CellAuthor(s): Shruti Bhatt, Marissa S. Pioso, Elyse Anne Olesinski, Binyam Yilma, Jeremy A. Ryan, Thelma Mashaka, Buon Leutz, Sophia Adamia, Haoling Zhu, Yanan Kuang, Abhishek Mogili, Abner J. Louissaint, Stephan R. Bohl, Annette S. Kim, Anita K. Mehta, Sneha Sanghavi, Youzhen Wang, Erick Morris, Ensar Halilovic, Cloud P. Paweletz (Source: Cancer Cell)
Source: Cancer Cell - November 20, 2020 Category: Cancer & Oncology Source Type: research

Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
Publication date: Available online 12 November 2020Source: Cancer CellAuthor(s): Ilaria Guccini, Ajinkya Revandkar, Mariantonietta D'Ambrosio, Manuel Colucci, Emiliano Pasquini, Simone Mosole, Martina Troiani, Daniela Brina, Raheleh Sheibani-Tezerji, Angela Rita Elia, Andrea Rinaldi, Nicolò Pernigoni, Jan Hendrik Rüschoff, Susanne Dettwiler, Angelo M. De Marzo, Emmanuel S. Antonarakis, Costanza Borrelli, Andreas E. Moor, Ramon Garcia-Escudero, Abdullah Alajati (Source: Cancer Cell)
Source: Cancer Cell - November 13, 2020 Category: Cancer & Oncology Source Type: research

Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
Publication date: Available online 12 November 2020Source: Cancer CellAuthor(s): Jichang Han, Meng Yu, Yiqin Bai, Jianzhong Yu, Fei Jin, Chen Li, Rong Zeng, Jinghong Peng, Ao Li, Xiaomin Song, Hao Li, Dianqing Wu, Lin Li (Source: Cancer Cell)
Source: Cancer Cell - November 13, 2020 Category: Cancer & Oncology Source Type: research