Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
Publication date: 13 July 2020Source: Cancer Cell, Volume 38, Issue 1Author(s): Johannes Gojo, Bernhard Englinger, Li Jiang, Jens M. Hübner, McKenzie L. Shaw, Olivia A. Hack, Sibylle Madlener, Dominik Kirchhofer, Ilon Liu, Jason Pyrdol, Volker Hovestadt, Emanuele Mazzola, Nathan D. Mathewson, Maria Trissal, Daniela Lötsch, Christian Dorfer, Christine Haberler, Angela Halfmann, Lisa Mayr, Andreas Peyrl (Source: Cancer Cell)
Source: Cancer Cell - July 14, 2020 Category: Cancer & Oncology Source Type: research

Cancer-type-Specific Bacteria: Freeloaders or Partners?
Publication date: Available online 9 July 2020Source: Cancer CellAuthor(s): K. Leigh Greathouse, Joshua K. Stone, Curtis C. Harris (Source: Cancer Cell)
Source: Cancer Cell - July 11, 2020 Category: Cancer & Oncology Source Type: research

Cell Lineage-Based Stratification for Glioblastoma
Publication date: Available online 9 July 2020Source: Cancer CellAuthor(s): Zilai Wang, Daochun Sun, Yu-Jung Chen, Xuanhua Xie, Yufeng Shi, Viviane Tabar, Cameron W. Brennan, Tejus A. Bale, Chenura D. Jayewickreme, Dan R. Laks, Sheila Alcantara Llaguno, Luis F. Parada (Source: Cancer Cell)
Source: Cancer Cell - July 11, 2020 Category: Cancer & Oncology Source Type: research

Oxidative Stress in Cancer
Publication date: Available online 9 July 2020Source: Cancer CellAuthor(s): John D. Hayes, Albena T. Dinkova-Kostova, Kenneth D. Tew (Source: Cancer Cell)
Source: Cancer Cell - July 11, 2020 Category: Cancer & Oncology Source Type: research

Immunogenomic Landscape of Hematological Malignancies
Publication date: Available online 9 July 2020Source: Cancer CellAuthor(s): Olli Dufva, Petri Pölönen, Oscar Brück, Mikko A.I. Keränen, Jay Klievink, Juha Mehtonen, Jani Huuhtanen, Ashwini Kumar, Disha Malani, Sanna Siitonen, Matti Kankainen, Bishwa Ghimire, Jenni Lahtela, Pirkko Mattila, Markus Vähä-Koskela, Krister Wennerberg, Kirsi Granberg, Suvi-Katri Leivonen, Leo Meriranta, Caroline Heckman (Source: Cancer Cell)
Source: Cancer Cell - July 11, 2020 Category: Cancer & Oncology Source Type: research

Digitalized Adaptation of Oncology Trials during and after COVID-19
Publication date: Available online 6 July 2020Source: Cancer CellAuthor(s): Guanqiao Li, Chen Yin, Yangzhong Zhou, Tongyan Wang, Jing Chen, Yang Liu, Ting Chen, Haixue Wang, Linqi Zhang, Xiaoyuan Chen (Source: Cancer Cell)
Source: Cancer Cell - July 7, 2020 Category: Cancer & Oncology Source Type: research

Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
Publication date: Available online 2 July 2020Source: Cancer CellAuthor(s): Ilgen Mender, Anli Zhang, Zhenhua Ren, Chuanhui Han, Yafang Deng, Silvia Siteni, Huiyu Li, Jiankun Zhu, Aishwarya Vemula, Jerry W. Shay, Yang-Xin Fu (Source: Cancer Cell)
Source: Cancer Cell - July 4, 2020 Category: Cancer & Oncology Source Type: research

SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
Publication date: Available online 2 July 2020Source: Cancer CellAuthor(s): Huairui Yuan, Ying Han, Xuege Wang, Ni Li, Qiuli Liu, Yuye Yin, Hanling Wang, Lulu Pan, Li Li, Kun Song, Tong Qiu, Qiang Pan, Qilong Chen, Guoying Zhang, Yi Zang, Minjia Tan, Jian Zhang, Qintong Li, Xiaoming Wang, Jun Jiang (Source: Cancer Cell)
Source: Cancer Cell - July 4, 2020 Category: Cancer & Oncology Source Type: research

Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
Publication date: Available online 25 June 2020Source: Cancer CellAuthor(s): Yang Tang, Gemin Fang, Fenghua Guo, Hui Zhang, Xiaoxu Chen, Liwei An, Min Chen, Li Zhou, Wenjia Wang, Tiantian Ye, Lei Zhou, Pingping Nie, Haijun Yu, Moubin Lin, Yun Zhao, Xinhua Lin, Zengqiang Yuan, Shi Jiao, Zhaocai Zhou (Source: Cancer Cell)
Source: Cancer Cell - June 27, 2020 Category: Cancer & Oncology Source Type: research

PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
Publication date: Available online 25 June 2020Source: Cancer CellAuthor(s): Yotaro Kudo, Masayuki Sugimoto, Esperanza Arias, Hiroaki Kasashima, Thekla Cordes, Juan F. Linares, Angeles Duran, Yuki Nakanishi, Naoko Nakanishi, Antoine L'Hermitte, Alex Campos, Nadia Senni, Tarmo Rooslid, Lewis R. Roberts, Ana Maria Cuervo, Christian M. Metallo, Michael Karin, Maria T. Diaz-Meco, Jorge Moscat (Source: Cancer Cell)
Source: Cancer Cell - June 27, 2020 Category: Cancer & Oncology Source Type: research

Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
Publication date: Available online 18 June 2020Source: Cancer CellAuthor(s): Basit Salik, Hangyu Yi, Nunki Hassan, Nancy Santiappillai, Binje Vick, Patrick Connerty, Alastair Duly, Toby Trahair, Andrew J. Woo, Dominik Beck, Tao Liu, Karsten Spiekermann, Irmela Jeremias, Jianlong Wang, Maria Kavallaris, Michelle Haber, Murray D. Norris, Dan A. Liebermann, Richard J. D'Andrea, Christopher Murriel (Source: Cancer Cell)
Source: Cancer Cell - June 20, 2020 Category: Cancer & Oncology Source Type: research

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer
Publication date: Available online 18 June 2020Source: Cancer CellAuthor(s): Luisa F. Escobar-Hoyos, Alex Penson, Ram Kannan, Hana Cho, Chun-Hao Pan, Rohit K. Singh, Lisa H. Apken, G. Aaron Hobbs, Renhe Luo, Nicolas Lecomte, Sruthi Babu, Fong Cheng Pan, Direna Alonso-Curbelo, John P. Morris, Gokce Askan, Olivera Grbovic-Huezo, Paul Ogrodowski, Jonathan Bermeo, Joseph Saglimbeni, Cristian D. Cruz (Source: Cancer Cell)
Source: Cancer Cell - June 20, 2020 Category: Cancer & Oncology Source Type: research

Clinically Actionable Strategies for Studying Neural Influences in Cancer
Publication date: Available online 11 June 2020Source: Cancer CellAuthor(s): Ihsan Ekin Demir, Carmen Mota Reyes, Wasfi Alrawashdeh, Güralp O. Ceyhan, Sylvie Deborde, Helmut Friess, Kivanc Görgülü, Rouzanna Istvanffy, David Jungwirth, Rohini Kuner, Maria Maryanovich, Shorook Na’ara, Simon Renders, Jami L. Saloman, Nicole N. Scheff, Hendrik Steenfadt, Pavel Stupakov, Vera Thiel, Divij Verma, Bengi Su Yilmaz (Source: Cancer Cell)
Source: Cancer Cell - June 18, 2020 Category: Cancer & Oncology Source Type: research

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
Publication date: Available online 11 June 2020Source: Cancer CellAuthor(s): Rui Su, Lei Dong, Yangchan Li, Min Gao, Li Han, Mark Wunderlich, Xiaolan Deng, Hongzhi Li, Yue Huang, Lei Gao, Chenying Li, Zhicong Zhao, Sean Robinson, Brandon Tan, Ying Qing, Xi Qin, Emily Prince, Jun Xie, Hanjun Qin, Wei Li (Source: Cancer Cell)
Source: Cancer Cell - June 12, 2020 Category: Cancer & Oncology Source Type: research

Pan-Cancer Early Detection: Hype or Hope?
Publication date: Available online 11 June 2020Source: Cancer CellAuthor(s): Sudhir Srivastava, Sam Hanash (Source: Cancer Cell)
Source: Cancer Cell - June 12, 2020 Category: Cancer & Oncology Source Type: research