MAT2A inhibition blocks the growth of MTAP-deleted cancer cells by reducing PRMT5-dependent mRNA splicing and inducing DNA damage
Publication date: Available online 14 January 2021Source: Cancer CellAuthor(s): Peter Kalev, Marc L. Hyer, Stefan Gross, Zenon Konteatis, Chi-Chao Chen, Mark Fletcher, Max Lein, Elia Aguado-Fraile, Victoria Frank, Amelia Barnett, Everton Mandley, Joshua Goldford, Yue Chen, Katie Sellers, Sebastian Hayes, Kate Lizotte, Phong Quang, Yesim Tuncay, Michelle Clasquin, Rachel Peters (Source: Cancer Cell)
Source: Cancer Cell - January 16, 2021 Category: Cancer & Oncology Source Type: research
Targeting pan-essential genes in cancer: challenges and opportunities
Publication date: Available online 14 January 2021Source: Cancer CellAuthor(s): Liang Chang, Paloma Ruiz, Takahiro Ito, William R. Sellers (Source: Cancer Cell)
Source: Cancer Cell - January 16, 2021 Category: Cancer & Oncology Source Type: research
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
Publication date: Available online 14 January 2021Source: Cancer CellAuthor(s): Yansen Xiao, Min Cong, Jiatao Li, Dasa He, Qiuyao Wu, Pu Tian, Yuan Wang, Shuaixi Yang, Chenxi Liang, Yajun Liang, Jili Wen, Yingjie Liu, Wenqian Luo, Xianzhe Lv, Yunfei He, Dong-dong Cheng, Tianhao Zhou, Wenjing Zhao, Peiyuan Zhang, Xue Zhang (Source: Cancer Cell)
Source: Cancer Cell - January 16, 2021 Category: Cancer & Oncology Source Type: research
The Landscape of Cell and Gene Therapies for Solid Tumors
Publication date: 11 January 2021Source: Cancer Cell, Volume 39, Issue 1Author(s): Shuhang Wang, Fa Sun, Huiyao Huang, Kun Chen, Qi-Jing Li, Lu Zhang, Enxiu Wang, Chen Wang, Hai Zhang, Andy Qingan Yuan, Bin Chen, Tao Deng, Yarong Liu, Jingwei Sun, Dongfang Liu, Yue Yu, Yuan Fang, Ning Jiang, Dawei Wu, Hong Fang (Source: Cancer Cell)
Source: Cancer Cell - January 12, 2021 Category: Cancer & Oncology Source Type: research
Exploration of Coding and Non-coding Variants in Cancer Using GenomePaint
Publication date: 11 January 2021Source: Cancer Cell, Volume 39, Issue 1Author(s): Xin Zhou, Jian Wang, Jaimin Patel, Marc Valentine, Ying Shao, Scott Newman, Edgar Sioson, Liqing Tian, Yu Liu, Samuel W. Brady, Diane Flasch, Xiaotu Ma, Yanling Liu, Robin Paul, Michael N. Edmonson, Michael C. Rusch, Chunliang Li, Suzanne J. Baker, John Easton, Jinghui Zhang (Source: Cancer Cell)
Source: Cancer Cell - January 12, 2021 Category: Cancer & Oncology Source Type: research
Biomolecular condensates and cancer
Publication date: Available online 7 January 2021Source: Cancer CellAuthor(s): Ann Boija, Isaac A. Klein, Richard A. Young (Source: Cancer Cell)
Source: Cancer Cell - January 8, 2021 Category: Cancer & Oncology Source Type: research
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence
Publication date: Available online 7 January 2021Source: Cancer CellAuthor(s): Eugen Dhimolea, Ricardo de Matos Simoes, Dhvanir Kansara, Aziz Al’Khafaji, Juliette Bouyssou, Xiang Weng, Shruti Sharma, Joseline Raja, Pallavi Awate, Ryosuke Shirasaki, Huihui Tang, Brian J. Glassner, Zhiyi Liu, Dong Gao, Jordan Bryan, Samantha Bender, Jennifer Roth, Michal Scheffer, Rinath Jeselsohn, Nathanael S. Gray (Source: Cancer Cell)
Source: Cancer Cell - January 8, 2021 Category: Cancer & Oncology Source Type: research
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
Publication date: Available online 7 January 2021Source: Cancer CellAuthor(s): Chen Huang, Lijun Chen, Sara R. Savage, Rodrigo Vargas Eguez, Yongchao Dou, Yize Li, Felipe da Veiga Leprevost, Eric J. Jaehnig, Jonathan T. Lei, Bo Wen, Michael Schnaubelt, Karsten Krug, Xiaoyu Song, Marcin Cieślik, Hui-Yin Chang, Matthew A. Wyczalkowski, Kai Li, Antonio Colaprico, Qing Kay Li, David J. Clark (Source: Cancer Cell)
Source: Cancer Cell - January 8, 2021 Category: Cancer & Oncology Source Type: research
Crosstown Traffic: Lymphodepleting Chemotherapy Drives CAR T Cells
Publication date: Available online 7 January 2021Source: Cancer CellAuthor(s): David M. Davies, John Maher (Source: Cancer Cell)
Source: Cancer Cell - January 8, 2021 Category: Cancer & Oncology Source Type: research
Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients
Publication date: Available online 5 January 2021Source: Cancer CellAuthor(s): Sultan Abdul-Jawad, Luca Baù, Thanussuyah Alaguthurai, Irene del Molino del Barrio, Adam G. Laing, Thomas S. Hayday, Leticia Monin, Miguel Muñoz-Ruiz, Louisa McDonald, Isaac Francos Quijorna, Duncan McKenzie, Richard Davis, Anna Lorenc, Julie Nuo En Chan, Sarah Ryan, Eva Bugallo-Blanco, Rozalyn Yorke, Shraddha Kamdar, Matthew Fish, Iva Zlatareva (Source: Cancer Cell)
Source: Cancer Cell - January 7, 2021 Category: Cancer & Oncology Source Type: research
Changes in Treatment Behavior during the COVID-19 Pandemic among Patients at a Cancer Hospital
Publication date: Available online 6 January 2021Source: Cancer CellAuthor(s): Yasuyoshi Sato, Yu Fujiwara, Naoki Fukuda, Brian Hayama, Yoshinori Ito, Shinji Ohno, Shunji Takahashi, COVID-19 Working Group of The Cancer Institute Hospital of Japanese Foundation for Cancer Research (Source: Cancer Cell)
Source: Cancer Cell - January 7, 2021 Category: Cancer & Oncology Source Type: research
Chromaffin Cells with Sympathoblast Signature: Too Similar to Keep Apart?
Publication date: Available online 31 December 2020Source: Cancer CellAuthor(s): Oscar C. Bedoya-Reina, Susanne Schlisio (Source: Cancer Cell)
Source: Cancer Cell - January 1, 2021 Category: Cancer & Oncology Source Type: research
Response to Kildsiute et al. and Bedoya-Reina and Schlisio
Publication date: Available online 31 December 2020Source: Cancer CellAuthor(s): Ran Yang, Wenqin Luo, Yong Zhan, Kai Li, Jia Wang, Rui Dong (Source: Cancer Cell)
Source: Cancer Cell - January 1, 2021 Category: Cancer & Oncology Source Type: research
Pitfalls of Applying Mouse Markers to Human Adrenal Medullary Cells
Publication date: Available online 31 December 2020Source: Cancer CellAuthor(s): Gerda Kildisiute, Matthew D. Young, Sam Behjati (Source: Cancer Cell)
Source: Cancer Cell - January 1, 2021 Category: Cancer & Oncology Source Type: research
Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
Publication date: Available online 31 December 2020Source: Cancer CellAuthor(s): Archis Bagati, Sushil Kumar, Peng Jiang, Jason Pyrdol, Angela E. Zou, Anze Godicelj, Nathan D. Mathewson, Adam N.R. Cartwright, Paloma Cejas, Myles Brown, Anita Giobbie-Hurder, Deborah Dillon, Judith Agudo, Elizabeth A. Mittendorf, X. Shirley Liu, Kai W. Wucherpfennig (Source: Cancer Cell)
Source: Cancer Cell - January 1, 2021 Category: Cancer & Oncology Source Type: research
