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Particulate yeast β-glucan Is internalized by RAW 264.7 macrophages and reduces the activity of the tumor-associated protease legumain
Publication date: Available online 24 June 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Lise Berven , Frode Miltzow Skjeldal , Kristian Prydz , Layla Mohammad Khader Zubaidi , Simon Ballance , Harald Thidemann Johansen , Anne Berit C. Samuelsen Yeast-derived β-glucans (Y-BG) are potential immune-modulating compounds able to activate macrophages. We investigated whether Y-BG affects the activity of a proteolytic enzyme, legumain, which is expressed in macrophages and involved in inflammatory conditions as well as in cancer development. RAW 264.7 macrophages were stimulated with either particu...
Source: Bioactive Carbohydrates and Dietary Fibre - July 1, 2015 Category: Food Science Source Type: research

Protective effect of extracellular polysaccharides from Grifola frondosa mycelium on CCl4-injured liver in vitro
Publication date: July 2015 Source:Bioactive Carbohydrates and Dietary Fibre, Volume 6, Issue 1 Author(s): Xiaolei Ma , Caojiao Li , Wentao Qi , Xiaorui Li , Shixia Wang , Xiaohong Cao , Chunling Wang In this paper, the protective effect of extracellular polysaccharides from Grifola frondosa mycelium (EXO-GFP) on liver injury induced by carbon tetrachloride (CCL4) was studied. As the study showed, EXO-GFP was mainly consisted of α-pyranoside glucans. Four monosaccharides including rhamnose, arabinose, xylose, glucose were contained, with the molar ratio at 0.028:0.031:0.030:8.98, respectively. The protective ro...
Source: Bioactive Carbohydrates and Dietary Fibre - July 1, 2015 Category: Food Science Source Type: research

Biological properties of apple pomace, orange bagasse and passion fruit peel as alternative sources of dietary fibre
Publication date: July 2015 Source:Bioactive Carbohydrates and Dietary Fibre, Volume 6, Issue 1 Author(s): Fernanda Teixeira Macagnan , Lucciélli Rodrigues dos Santos , Bruna Sampaio Roberto , Fernanda Aline de Moura , Marilia Bizzani , Leila Picolli da Silva Several health benefits are associated with adequate intake of dietary fibre; however, the constitution of the fibre fraction is different for each vegetable, which influences their physico-chemical properties and, consequently, their physiological effects on the human organism. The present study evaluated the effect of different sources of dietary fibre fr...
Source: Bioactive Carbohydrates and Dietary Fibre - July 1, 2015 Category: Food Science Source Type: research

Health benefits of konjac glucomannan with special focus on diabetes
Publication date: April 2015 Source:Bioactive Carbohydrates and Dietary Fibre, Volume 5, Issue 2 Author(s): Bakht Ramin Shah , Bin Li , Ling Wang , Shilin Liu , Yan Li , Xu Wei , Jin Weiping , Li Zhenshun Diabetes mellitus (DM) is one of the most common non-communicable diseases worldwide. The incidence and prevalence of type 2 diabetes is on rise due to population growth, aging, urbanization, and well-known risk factors like obesity, smoking, unhealthy dietary habits and physical inactivity. Effective dietary strategies have an influence on decreasing postprandial plasma glucose burden, including the use of hi...
Source: Bioactive Carbohydrates and Dietary Fibre - April 29, 2015 Category: Food Science Source Type: research

Investigation of the factors influencing the molecular weight of porphyran and its associated antifungal activity
Publication date: April 2015 Source:Bioactive Carbohydrates and Dietary Fibre, Volume 5, Issue 2 Author(s): Saurabh Bhatia , Kiran Sharma , Kalpana Nagpal , Tanmoy Bera In the present study various extraction methodologies have been adopted to derive sulfated polysaccharides (SPs) called as porphyran (POR) from low tide (LT) and high tide (HT) samples of Porphyra vietnamensis. Initially various taxonomical differences among LT and HT samples of P. vietnamensis were evaluated. Later on various physico-chemical and antifungal properties were determined. Our results suggested that P. vietnamensis collected during LT y...
Source: Bioactive Carbohydrates and Dietary Fibre - April 22, 2015 Category: Food Science Source Type: research

Mmy table citatiInvestigation of the factors influencing the molecular weight of porphyran and its associated antifungal activity
Publication date: Available online 4 April 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Saurabh Bhatia , Kiran Sharma , Kalpana Nagpal , Tanmoy Bera In the present study various extraction methodologies have been adopted to derive sulfated polysaccharides (SPs) called as porphyran (POR) from low tide (LT) and high tide (HT) samples of Porphyra vietnamensis. Initially various taxonomical differences among LT and HT samples of P. vietnamensis were evaluated. Later on various physico-chemical and antifungal properties were determined. Our results suggested that P. vietnamensis collected during LT y...
Source: Bioactive Carbohydrates and Dietary Fibre - April 4, 2015 Category: Food Science Source Type: research

scFOS SUPPLEMENTED FOLLOW-ON FORMULA IN HEALTHY INFANTS: IMPACT ON VACCINE SPECIFIC FAECAL SECRETORY IGA RESPONSE, FAECAL BIFIDOBACTERIA, GROWTH AND DIGESTIVE TOLERANCE
Conclusions A follow-on milk formula supplemented with scFOS modulates intestinal microbiota via an increase of faecal bifidobacteria concentration, while no effect on sIgA concentrations could be demonstrated. scFOS addition elicited normal digestive tolerance and normal growth suggesting it can be used safely at 5g/L in infants after 4 months of age. (Source: Bioactive Carbohydrates and Dietary Fibre)
Source: Bioactive Carbohydrates and Dietary Fibre - April 4, 2015 Category: Food Science Source Type: research

Protective effect of xylooligosaccharides from corncob on 1,2-dimethylhydrazine induced colon Cancer in rats
Publication date: Available online 1 April 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Ayyappan A. Aachary , Duraiswamy Gobinath , Krishnapura Srinivasan , Siddalingaiya G. Prapulla The anti-carcinogenic effect of the emerging prebiotic xylooligosaccharides (XOS) was evaluated in an animal model. Experimental colonic cancer was induced by three successive injections of 1,2-dimethylhydrazine (DMH) (20mg/ kg body weight) at weekly intervals in male Wistar rats. XOS was included at 5 and 10% (w/w) in the diets of DMH-administered animals for 45 days. Beneficial effects of dietary XOS were observed...
Source: Bioactive Carbohydrates and Dietary Fibre - April 1, 2015 Category: Food Science Source Type: research

An alternative strategy for structural glucanomics using β-gluco-oligosaccharides from the brown algae Ecklonia stolonifera as models
Publication date: Available online 28 March 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Wataru Sumiyoshi , Nobumitsu Miyanishi , Shin-ichi Nakakita , Shoko Tsutsui , Keita Yamada , Yukari Nakakita , Shin Yoshioka , Masakatsu Asao , Jun Hirabayashi Studies of β-glucans are often hampered by their structural diversity and complexity, which is problematic because interest in their effects on animal cells has increased in recent years. Herein, we present a comprehensive strategy for structural characterization of branched β-glucans, and as a proof-of-concept study, characterized laminarin an...
Source: Bioactive Carbohydrates and Dietary Fibre - March 28, 2015 Category: Food Science Source Type: research

Effect of depolymerised konjac glucomannan on wound healing
The objective of this work was to determine the effects of ingested depolymerised glucomannans on wound healing. Mice were divided into four groups of twenty each: control - drinking water; control - drinking water containing 5% (w/v) glucomannan hydrolysate (GMH); test - drinking water with punched ear and; test - drinking water containing 5% (w/v) GMH with punched ear. Healing scores were recorded over eight days while body weight was taken four times over the trial period. There was faster healing for the group drinking water containing GMH. The consumption of hydrolysed glucomannan may encourage wound healing due to a ...
Source: Bioactive Carbohydrates and Dietary Fibre - March 28, 2015 Category: Food Science Source Type: research

Studies on functional and antioxidant property of dietary fibre extracted from defatted sesame Husk, rice bran and flaxseed
This study examined the effectiveness of a dietary fibre preparation, derived from these sources, as a functional ingredient with potential of antioxidant activity. The observations established that dietary fibre from defatted flaxseed and rice bran had higher water binding, oil binding and emulsifying capacity compared to sesame husk dietary fibre. However, rice bran and sesame husk fibre were found to be less viscous than flaxseed fibre. Whereas in case of antioxidant activity rice bran fibre showed higher activity than flaxseed and sesame husk. The study confirms that the dietary fibre preparation from defatted sesame h...
Source: Bioactive Carbohydrates and Dietary Fibre - March 28, 2015 Category: Food Science Source Type: research

Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): Part III–Immunomodulatory activity in vitro
Publication date: April 2015 Source:Bioactive Carbohydrates and Dietary Fibre, Volume 5, Issue 2 Author(s): Hai-lan Cai , Xiao-jun Huang , Shao-ping Nie , Ming-yong Xie , Glyn O. Phillips , Steve. W. Cui Dendrobium officinale, ranked as the first of “Nine kinds of Chinese medicinal herbs”, has been used for centuries to treat a variety of health problems. However, less is known about the active components which confer the therapeutic properties of D. officinale. In the present study, the effects of aqueous extract, crude polysaccharide and purified polysaccharide from the stems of D. officinale (Dendronan®)...
Source: Bioactive Carbohydrates and Dietary Fibre - February 9, 2015 Category: Food Science Source Type: research

Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): Part V. Fractionation and structural heterogeneity of different fractions
In conclusion, all the four fractions were different in detailed structural features, although they shared the same major structure as 2,3-O-acetyl-glucomannan. (Source: Bioactive Carbohydrates and Dietary Fibre)
Source: Bioactive Carbohydrates and Dietary Fibre - January 24, 2015 Category: Food Science Source Type: research

Modelling the effect of undigested dietary carbohydrate on the health and function of the large bowel
Publication date: Available online 5 January 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Douglas Rosendale , Indrakumar Vetharaniam , Adrian L. Cookson , Nicole Roy Consuming dietary fibre confers a number of large bowel health benefits through various interacting mechanisms. Here we describe and mathematically model how these key mechanisms respond to changes in the concentration of fibre consumed. The key markers of bowel health and function, short chain fatty acid (SCFA) and branched chain fatty acid (BCFA) concentrations, faecal bulk, transit time and pH are interrelated and captured in a m...
Source: Bioactive Carbohydrates and Dietary Fibre - January 7, 2015 Category: Food Science Source Type: research

Effect of dietary oat β-glucan on high-fat diet induced obesity in HFA mice
Publication date: Available online 5 January 2015 Source:Bioactive Carbohydrates and Dietary Fibre Author(s): Hu Xin-Zhong , Sheng Xia-lu , Li Xiao-ping , Liu Liu , Zheng Jian-mei , Chen Xing-yun Obesity has been suggested to be related to high intake of fat and low intake of fiber. Here we show the effect of oat β-glucan, a water soluble dietary fiber, in preventing high-fat diet induced obesity in human flora-associated (HFA) mice. HFA mice fed with high-fat diet for 8 weeks, significantly increased body weight, epididymal and subcutaneous adipose tissue weight compared with HFA mice in normal diet group (p&am...
Source: Bioactive Carbohydrates and Dietary Fibre - January 7, 2015 Category: Food Science Source Type: research