The new Journal of Applied & Translational Genomics: No, not just another new journal
Publication date: 1 September 2014 Source:Applied & Translational Genomics, Volume 3, Issue 3 Author(s): Carol Isaacson Barash (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Data acquisition and data/knowledge sharing in global genomic studies
Publication date: Available online 11 September 2014 Source:Applied & Translational Genomics Author(s): Charles Rotimi , Nicola Mulder (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
The paradigm shift to an “open” model in drug development
Publication date: Available online 16 September 2014 Source:Applied & Translational Genomics Author(s): Regina Au The rising cost of healthcare, the rising cost for drug development, the patent cliff for Big pharma, shorter patent protection, decrease reimbursement, and the recession have made it more difficult for the pharmaceutical and biotechnology industry to develop drugs. Due to the unsustainable amount of time and money in developing a drug that will have a significant return on investment (ROI) it has become hard to sustain a robust pipeline. The industry is transforming its business model to meet thes...
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Genomic Knowledge Sharing: A review of the ethical and legal issues
This article argues that if we take duties of patients to share information seriously, we must also consider duties on the part of information holders about how they protect and use information. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
A collaborative approach to develop a multi-omics data analytics platform for translational research
Publication date: Available online 16 September 2014 Source:Applied & Translational Genomics Author(s): Axel Schumacher , Tamas Rujan , Jens Hoefkens The integration and analysis of large datasets in translational research has become an increasingly challenging problem. We propose a collaborative approach to integrate established data management platforms with existing analytical systems to fill the hole in the value chain between data collection and data exploitation. Our proposal in particular ensures data security and provides support for widely distributed teams of researchers. As a successful example fo...
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
HINARI: Opening access in biomedicine and health
Publication date: Available online 17 September 2014 Source:Applied & Translational Genomics Author(s): Florence Robertson (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
To share or not to share is the question
This article discusses recent developments in the formulation of best practice guidelines for data sharing. Particular attention is focused on the Global Alliance for Genomics and Health (GA4GH) draft Framework of Conduct for Data Sharing. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Distributing the future: The weak justifications for keeping human genomic databases secret and the challenges and opportunities in reverse engineering them
Publication date: Available online 19 September 2014 Source:Applied & Translational Genomics Author(s): Misha Angrist , Robert Cook-Deegan (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
What is Translational Genomics? Going Beyond the Bedside to Improving Individual and Population Health
Publication date: Available online 19 September 2014 Source:Applied & Translational Genomics Author(s): Sheri D. Schully , Muin J. Khoury (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
The need to redefine genomic data sharing: A focus on data accessibility
Publication date: Available online 28 September 2014 Source:Applied & Translational Genomics Author(s): Tempest A. van Schaik , Nadezda V. Kovalevskaya , Elena Protopapas , Hamza Wahid , Fiona G.G. Nielsen DNAdigest's mission is to investigate and address the issues hindering efficient and ethical genomic data sharing in the human genomics research community. We conducted contextual interviews with human genomics researchers in clinical, academic or industrial R&D settings about their experience with accessing and sharing human genomic data. The qualitative interviews were followed by an online sur...
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
The locked genomes: A perspective from Arabia
Publication date: Available online 28 September 2014 Source:Applied & Translational Genomics Author(s): Fahd Al-Mulla (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Global Genomic Knowledge Sharing- A Call for Affirmative Action
Publication date: Available online 30 September 2014 Source:Applied & Translational Genomics Author(s): Anthony Flynn , Dawn van Dam (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
Innovate or die!: Genomic data and the electronic health record (EHR)
Publication date: Available online 2 October 2014 Source:Applied & Translational Genomics Author(s): Rebecca Fein The sharing of patient data, such as test results, is important for appropriately treating patients. Inclusion of this data allows for clinical error prevention, particularly if a new clinician becomes involved. If genetic information, including family history or genetic test results, is not accessible to treating physicians, care may suffer. Innovation is needed to address the problem of lack of access to important data, such as genomic test results, not structured to fit into an EHR. Without data...
Source: Applied and Translational Genomics - October 12, 2014 Category: Genetics & Stem Cells Source Type: research
