Empowered Genome Community: Leveraging a bioinformatics platform as a citizen-scientist collaboration tool
Publication date: Available online 5 September 2015 Source:Applied & Translational Genomics Author(s): Katherine Wendelsdorf, Sohela Shah There is on-going effort in the biomedical research community to leverage Next Generation Sequencing (NGS) technology to identify genetic variants that affect our health. The main challenge facing researchers is getting enough samples from individuals- either sick or healthy- to be able to reliably identify the few variants that are causal for a phenotype among all other variants typically seen among individuals. At the same time, more and more individuals are having thei...
Source: Applied and Translational Genomics - September 5, 2015 Category: Genetics & Stem Cells Source Type: research
TranSMART Foundation Datathon 1.0: The Cross Neurodegenerative Diseases Challenge
Publication date: Available online 1 September 2015 Source:Applied & Translational Genomics Author(s): Carol Isaacson Barash, Keith Elliston, Rudy Potenzone (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - September 1, 2015 Category: Genetics & Stem Cells Source Type: research
What is translational bioinformatics?
Publication date: Available online 28 August 2015 Source:Applied & Translational Genomics Author(s): Eric R. Londin, Carol Isaacson Barash (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 28, 2015 Category: Genetics & Stem Cells Source Type: research
Developing educational iPhone, android and windows smartphone cross-platform apps to facilitate understanding of clinical genomics terminology
Publication date: Available online 28 August 2015 Source:Applied & Translational Genomics Author(s): Adam P. Tobias, Edward S. Tobias (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 28, 2015 Category: Genetics & Stem Cells Source Type: research
Interdisciplinary training to build an informatics workforce for precision medicine
We present a collaborative model of training that has the potential to produce a workforce prepared for the challenges of implementing precision medicine. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 8, 2015 Category: Genetics & Stem Cells Source Type: research
Developmental neurotoxic effects of Malathion on 3D neurosphere system
This study confirms the DNT effects of Malathion on 3D neurosphere model. Further epidemiological studies will be needed to link these results to human exposure and effects data. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 7, 2015 Category: Genetics & Stem Cells Source Type: research
The Problem with Big Data in Translational Medicine. A review of where we've been and the possibilities ahead
Publication date: Available online 5 August 2015 Source:Applied & Translational Genomics Author(s): Les Jordan Understanding the parallel evolutions of Big Data and Translational Medicine, and the types of disruptive technology that bring them together, requires a look back at their evolution and a discussion of the hindrances in applying big data techniques to translational medicine. That will allow a look into the future, at the concept of the “Complete Health Record” and how that may change the very nature of translational medicine. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 7, 2015 Category: Genetics & Stem Cells Source Type: research
SInterdisciplinary training to build an informatics workforce for Precision Medicine
We present a collaborative model of training that has the potential to produce a workforce prepared for the challenges of implementing precision medicine. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 5, 2015 Category: Genetics & Stem Cells Source Type: research
Atoms, Bits, and Cells
Publication date: Available online 4 August 2015 Source:Applied & Translational Genomics Author(s): David Glazer (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - August 5, 2015 Category: Genetics & Stem Cells Source Type: research
Developmental neurotoxic effects of malathion on 3D neurospheres system
This study confirms the DNT effects of Malathion on 3D neurospheres model. Further epidemiological studies will be needed to link these results to human exposure and effects data. (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - July 29, 2015 Category: Genetics & Stem Cells Source Type: research
Neurogenomics: An opportunity to integrate neuroscience, genomics and bioinformatics research in Africa
Publication date: Available online 22 July 2015 Source:Applied & Translational Genomics Author(s): Thomas K. Karikari, Jelena Aleksic Modern genomic approaches have made enormous contributions to improving our understanding of the function, development and evolution of the nervous system, and the diversity within and between species. However, most of these research advances have been recorded in countries with advanced scientific resources and funding support systems. On the contrary, little is known about, for example, the possible interplay between different genes, non-coding elements and environmental fa...
Source: Applied and Translational Genomics - July 22, 2015 Category: Genetics & Stem Cells Source Type: research
Genome interpretation: Clinical correlation is recommended
Publication date: Available online 22 July 2015 Source:Applied & Translational Genomics Author(s): Michael M. Segal (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - July 22, 2015 Category: Genetics & Stem Cells Source Type: research
Ethical issues associated with genetic counseling in the context of adolescent psychiatry
Publication date: Available online 27 June 2015 Source:Applied & Translational Genomics Author(s): Jane Ryan, Alice Virani, Jehannine C. Austin Genetic counseling is a well-established healthcare discipline that provides individuals and families with health information about disorders that have a genetic component in a supportive counseling encounter. It has recently been applied in the context of psychiatric disorders (like schizophrenia, bipolar disorder, schizoaffective disorder, obsessive compulsive disorder, depression and anxiety) that typically appear sometime during later childhood through to earl...
Source: Applied and Translational Genomics - July 20, 2015 Category: Genetics & Stem Cells Source Type: research
Targeted NGS meets expert clinical characterization: Efficient diagnosis of spastic paraplegia type 11
Publication date: Available online 26 June 2015 Source:Applied & Translational Genomics Author(s): Cristina Castro-Fernández , Manuel Arias , Patricia Blanco-Arias , Luis Santomé-Collazo , Jorge Amigo-Lechuga , Ángel Carracedo , Maria-Jesús Sobrido (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - June 27, 2015 Category: Genetics & Stem Cells Source Type: research
Applied and translational neurogenomics
Publication date: Available online 23 June 2015 Source:Applied & Translational Genomics Author(s): María-Jesús Sobrido , Wael M.Y. Mohamed (Source: Applied and Translational Genomics)
Source: Applied and Translational Genomics - June 24, 2015 Category: Genetics & Stem Cells Source Type: research
