The spectrum of childhood neoplasms – Evaluation of 161 cases in surgical pathology department
Publication date: Available online 21 August 2015 Source:Apollo Medicine Author(s): V.B. Gite, M.A. Dhakane Although major cause of childhood morbidity and mortality in the developing world is still malnutrition and infections, pediatric neoplasms are also rising in number. Although pediatric neoplasms occur infrequently, they present a challenging diagnostic and therapeutic problem. Unfamiliarity with these conditions may lead to the erroneous diagnosis and unnecessary aggressive therapy. This was a retrospective analysis of 161 cases of pediatric tumors, both benign and malignant, in surgical pathology department...
Source: Apollo Medicine - August 22, 2015 Category: Journals (General) Source Type: research

Atypical presentation of rhinosporidiosis as oropharyngeal polyp
We report a case of rhinosporidiosis with atypical presentation as an oropharyngeal polyp. (Source: Apollo Medicine)
Source: Apollo Medicine - August 22, 2015 Category: Journals (General) Source Type: research

Current evidence for laparoscopic surgery in colorectal cancers
Publication date: Available online 21 August 2015 Source:Apollo Medicine Author(s): Laletendu Mahapatra, Amanjeet Singh The article lays an emphasis on the laparoscopic surgical method used to treat colorectal cancer. It reviews the current status of the laparoscopic colorectal surgeries and recommendation of evidences for short- and long-term outcome. The early results were against laparoscopic approach. There was a need of properly designed study to validate or invalidate these findings. Seven large-scale trials compared laparoscopic and open colectomy for colon carcinoma and examined short-term and long-term out...
Source: Apollo Medicine - August 22, 2015 Category: Journals (General) Source Type: research

A rare de novo duplication of chromosome 21q22.12→q22.3 associated with Down syndrome – A case report
Publication date: Available online 21 August 2015 Source:Apollo Medicine Author(s): R.N. Makroo, M. Chowdhry, M. Kumar, D. Rani, Y. Thakur, M. Singh Genetics of Down syndrome (DS): (A) The classical trisomy 21 is caused by a meiotic nondisjunction event. (B) Mosaicism, used to describe the presence of more than one type of cell in a person, is usually described as a percentage. Mosaic DS occurs when some of the cells in the body are normal, and some cells have trisomy 21. This is the cause of 1–2% of the observed DS. There is evidence that mosaic DS may cause less developmental delay, on average, than ful...
Source: Apollo Medicine - August 22, 2015 Category: Journals (General) Source Type: research

An overview of colorectral cancer
Publication date: Available online 21 August 2015 Source:Apollo Medicine Author(s): Nipun Choudhry, Ankita Kaushal In this article, the pathogenesis, stages, and management of colorectal cancer (CRC) are reviewed. A concise overview of the known risk factors related with CRC is provided. CRC is the second most common cause of cancer death in UK. There are several factors considered to be causally associated with the development of CRC. For example, the risk of CRC is clearly increased by a Western diet. High quality surgery is of paramount importance in gaining good outcomes, but adjuvant chemotherapy and radiother...
Source: Apollo Medicine - August 22, 2015 Category: Journals (General) Source Type: research

Kirner's deformity – A case report
Publication date: Available online 19 August 2015 Source:Apollo Medicine Author(s): Rakesh Gujjar, Vikram Khanna, Raja Kollu, Raju Vaishya Kirner's deformity is a rare entity and is a cosmetic menace. It consists of radio-volar curving of the distal phalynx of the little finger. It is a painless deformity, and generally there is no functional impairment. It is generally a clinical diagnosis and confirmed radiographically. Here, we present a case of Kirner's deformity in a 12-year-old male patient. There was no pain or functional impairment in the patient. The patient was distressed with the cosmetic appearance ...
Source: Apollo Medicine - August 19, 2015 Category: Journals (General) Source Type: research

Molecular diagnosis of H1N1 virus
Conclusion The molecular testing of H1N1 patients helped the clinicians in timely diagnosis and treatment of these patients during the pandemic surveillance. The RT-PCR test has higher sensitivity and specificity; hence it is considered to be the best tool to use during the pandemic surveillance, as compared to the any other commercial antigen-based tests, which show a variable performance, with the sensitivities of tests from different manufacturers ranging from 9 to 77%. (Source: Apollo Medicine)
Source: Apollo Medicine - August 18, 2015 Category: Journals (General) Source Type: research

Obstructed defecation syndrome
Publication date: Available online 13 August 2015 Source:Apollo Medicine Author(s): Brij B. Agarwal Obstructed defecation syndrome (ODS) is a functional disorder leading to the sensing of outlet obstruction in the absence of any pathological findings. In this article, we also provide the etiology of acquired constipation. Constipation is a very common presentation by the patients of a practicing surgeon. Any constipation that defies the existing understanding merits consideration for its evaluation for ODS. Constipation can be of primary or secondary variety. After clinically excluding the usual causes of constipatio...
Source: Apollo Medicine - August 14, 2015 Category: Journals (General) Source Type: research

Problem of colorectal cancer in India and issues related to management
This article also deals specifically with the problem of rectal cancer in young Indians. Furthermore, the impact of minimal access CRC surgery and cutting edge issues in CRC surgery such as approach to complete responders after neo-adjuvant treatment in rectal cancer, concepts in sphincter preservation, and dealing with metastatic CRC are also addressed. Lastly, modern molecular biology with a clinical relevance and modern surgical approaches such as TEMS and TAMIS are also discussed. (Source: Apollo Medicine)
Source: Apollo Medicine - August 14, 2015 Category: Journals (General) Source Type: research

Role of Robotic Partial Nephrectomy in the treatment of renal cell carcinoma
This article lays an emphasis on the Role of Robotic Partial Nephrectomy in the treatment of renal cell carcinoma. The increasing radiological detection of histological low-grade low-stage renal masses has presented a challenging task to the practising urologist. Nephron sparing surgery (NSS) not only preserves the kidney but also allows safe removal of tumour of unknown malignant potential without removing the kidney. Advent of robotic technology and evolution of surgical technique together have offered to serve patients with these tumours, yet a large number of which are asymptomatic at the time of diagnosis. Centres whi...
Source: Apollo Medicine - August 14, 2015 Category: Journals (General) Source Type: research

Ascending aortic aneurysm and its clinical significance: A case report
Publication date: Available online 14 August 2015 Source:Apollo Medicine Author(s): Saju B. Cherian, Aruna Jyothi Gandhalam, M. Bhavani, P. Rohit Kumar, Vaishnavi Reddy Aorta, the major conductance vessel of the body, can be affected by a variety of pathologic processes leading to aneurysm, dissection, or ischemic syndromes. There has been a drastic increase in the incidence of aortic aneurysm making it the 18th most common cause for death. When ignored, the patients’ condition might worsen leading to death due to rupture and hemorrhage. Here we report a case of ascending aortic aneurysm affecting the aorti...
Source: Apollo Medicine - August 14, 2015 Category: Journals (General) Source Type: research

Sexual dysfunction due to SSRI antidepressants: How to manage?
Publication date: Available online 5 August 2015 Source:Apollo Medicine Author(s): Siddharth Sarkar, Seshadri Harihar, Bichitra Nanda Patra Selective Serotonin Reuptake Inhibitors (SSRIs) are a group of commonly prescribed antidepressants in clinical practice. Sexual dysfunction is a common side effect of SSRIs, which often goes unrecognized but adversely affects the quality of life of the patient. This review takes a look at the occurrence of sexual dysfunction among patients receiving SSRIs from a clinical viewpoint. The review explores into the possible reasons of such a dysfunction and the differential diagno...
Source: Apollo Medicine - August 7, 2015 Category: Journals (General) Source Type: research

A hidden cause of troublesome finger pain in an adult
We present a case of middle-aged man with agonizing pain under the nail bed of ring finger. Clinical diagnosis was made by the history, localized tenderness, and MRI findings. Excision of nail bed allowed us to remove the tumor from subungal bed and complete resolution of the symptoms. Histopathology confirmed the diagnosis of a glomus tumor. (Source: Apollo Medicine)
Source: Apollo Medicine - August 2, 2015 Category: Journals (General) Source Type: research

Gall stone ileus as a cause of intestinal obstruction in an obese elderly male
We present a case of 87-year-old overweight male who presented to us with intestinal obstruction. He was found to have the classical sings of gall stone ileus (pneumobilia, intestinal obstruction & gall stones in the distal ileum). He was managed with a single stage procedure. Here we also describe the available literature and the various treatment options available for the same. (Source: Apollo Medicine)
Source: Apollo Medicine - July 23, 2015 Category: Journals (General) Source Type: research

Tandem kidney
Publication date: Available online 27 June 2015 Source:Apollo Medicine Author(s): Praveen Pushkar , Anshuman Agarwal (Source: Apollo Medicine)
Source: Apollo Medicine - June 27, 2015 Category: Journals (General) Source Type: research