Risk for Postcolonoscopy Irritable Bowel Syndrome in Patients with and without Antibiotic Exposure
In this study involving 408,714 individuals, 24,617 (6.0%) individuals were exposed to antibiotics. After using propensity score matching to balance potential confounding factors, the authors found that the incidence of IBS in patients exposed to antibiotics was similar to that of patients who were not exposed to antibiotics (hazard ratio, 1.11; 95% confidence interval [CI], 0.89 –1.39), but the use of antibiotics was weakly related to the composite outcome (hazard ratio, 1.12; 95% CI, 1.02–1.24). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 8, 2021 Category: Gastroenterology Authors: Zhihua Liu, Chao Li Tags: Letter to the Editor Source Type: research

Risk for Post-Colonoscopy Irritable Bowel Syndrome in Patients with and without Antibiotic Exposure
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 8, 2021 Category: Gastroenterology Authors: Zhihua Liu, Chao Li Source Type: research

Is Late Detection of Hepatocellular Cancer Associated with Better Clinical Outcome?
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 8, 2021 Category: Gastroenterology Authors: Waseem Amjad, Dong J. Seo Source Type: research

Reply to COVID-19 morbidity and severity in patients with non-alcoholic fatty liver disease in South Korea: a nationwide cohort study
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 8, 2021 Category: Gastroenterology Authors: Liping Chen, Zhenyu Fan, Jilin Cheng Source Type: research

Effectiveness of Reinduction and/or Dose Escalation of Ustekinumab in Crohn ’s Disease: A Systematic Review and Meta-analysis
Patients with Crohn ’s disease (CD) treated with ustekinumab who experience inadequate response, or loss of response after standard induction and/or maintenance dosing may benefit from dose escalation. We conducted a systematic review and meta-analysis examining the effectiveness of reinduction and/or dose interval s hortening of ustekinumab in patients with active CD despite standard induction and maintenance. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 7, 2021 Category: Gastroenterology Authors: Joseph Meserve, Christopher Ma, Parambir S. Dulai, Vipul Jairath, Siddharth Singh Source Type: research

Effectiveness of Re-induction and/or Dose Escalation of Ustekinumab in Crohn ’s Disease: A Systematic Review and Meta-analysis
Patients with Crohn ’s disease (CD) treated with ustekinumab who experience inadequate response, or loss of response after standard induction and/or maintenance dosing may benefit from dose escalation. We conducted a systematic review and meta-analysis examining the effectiveness of re-induction and/or dose interval shortening of ustekinumab in patients with active CD despite standard induction and maintenance. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 7, 2021 Category: Gastroenterology Authors: Joseph Meserve, Christopher Ma, Parambir S. Dulai, Vipul Jairath, Siddharth Singh Source Type: research

Clinical Utility of Magnetic Resonance Imaging Biomarkers for Identifying Nonalcoholic Steatohepatitis Patients at High Risk of Progression: A Multicenter Pooled Data and Meta-Analysis
Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide. NAFLD is associated with excess risk of all-cause mortality, and its progression to nonalcoholic steatohepatitis (NASH) and fibrosis accounts for a growing proportion of cirrhosis and hepatocellular cancer and thus is a leading cause of liver transplant worldwide. Noninvasive precise methods to identify patients with NASH and NASH with significant disease activity and fibrosis are crucial when the disease is still modifiable. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 6, 2021 Category: Gastroenterology Authors: Anneli Andersson, Matt Kelly, Kento Imajo, Atsushi Nakajima, Jonathan A. Fallowfield, Gideon Hirschfield, Michael Pavlides, Arun J. Sanyal, Mazen Noureddin, Rajarshi Banerjee, Andrea Dennis, Stephen Harrison Source Type: research

Clinical utility of MRI biomarkers for identifying NASH patients at high risk of progression: A multi-center pooled data and meta-analysis
Non-alcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide. NAFLD is associated with excess risk of all-cause mortality, and its progression to non-alcoholic steatohepatitis (NASH) and fibrosis accounts for a growing proportion of cirrhosis and hepatocellular cancer and thus is a leading cause of liver transplant worldwide. Non-invasive precise methods to identify patients with NASH and NASH with significant disease activity and fibrosis when the disease is still modifiable are crucial. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 6, 2021 Category: Gastroenterology Authors: Anneli Andersson, Matt Kelly, Kento Imajo, Atsushi Nakajima, Jonathan A. Fallowfield, Gideon Hirschfield, Michael Pavlides, Arun J. Sanyal, Mazen Noureddin, Rajarshi Banerjee, Andrea Dennis, Stephen Harrison Source Type: research

Gender and Other Factors Associated with Endoscopy Volume Among U.S. Gastroenterology Fellows
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 6, 2021 Category: Gastroenterology Authors: Adrienne Lenhart, Frank Chen, Ashwinee Condon, Ani Kardashian, Najwa El-Nachef, UCLA GI Division Biostatistics, Lin Chang Source Type: research

Clinical utility of MRI biomarkers for identifying NASH patients ’ high risk of progression: A multi-center pooled data and meta-analysis
Non-alcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide. NAFLD is associated with excess risk of all-cause mortality, and its progression to non-alcoholic steatohepatitis (NASH) and fibrosis accounts for a growing proportion of cirrhosis and hepatocellular cancer and thus is a leading cause of liver transplant worldwide. Non-invasive precise methods to identify patients with NASH and NASH with significant disease activity and fibrosis when the disease is still modifiable are crucial. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 6, 2021 Category: Gastroenterology Authors: Anneli Andersson, Matt Kelly, Kento Imajo, Atsushi Nakajima, Jonathan A. Fallowfield, Gideon Hirschfield, Michael Pavlides, Arun J. Sanyal, Mazen Noureddin, Rajarshi Banerjee, Andrea Dennis, Stephen Harrison Source Type: research

Serum Fibrosis Tests Guide Prognosis in Metabolic Dysfunction –Associated Fatty Liver Disease Patients Referred From Primary Care
We examined the accuracy of noninvasive tests as screening tools for the prediction of outcomes in MAFLD patients referre d from primary care. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 5, 2021 Category: Gastroenterology Authors: Zhengyi Wang, Luis Calzadilla Bertot, Gary P. Jeffrey, John Joseph, George Garas, Bastiaan de Boer, Yi Huang, Gerry MacQuillan, Michael Wallace, Briohny Smith, Leon A. Adams Source Type: research

Coffee consumption is associated with lower liver stiffness: a nationally representative study
Coffee is associated with a reduced risk of liver disease. This association is limited by important sources of confounding such as recall bias, healthy-user bias, and indirect measures of liver outcomes or health. We aimed to examine the impact of coffee consumption with liver fibrosis and steatosis in a nationally representative sample. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 5, 2021 Category: Gastroenterology Authors: Sebastian Niezen, Manaav Mehta, Z. Gordon Jiang, Elliot B. Tapper Source Type: research

An Approach to the Primary and Secondary Prevention of Gastric Cancer in the United States
/Aims: Gastric cancer (GC) remains a leading cause of mortality among certain racial, ethnic, and immigrant groups in the United States (US). The majority of GCs are diagnosed at advanced stages, and overall survival remains poor. There exist no structured national strategies for GC prevention in the US. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 5, 2021 Category: Gastroenterology Authors: Robert J. Huang, Meira Epplein, Chisato Hamashima, Il Ju Choi, Eunjung Lee, Dennis Deapen, Yanghee Woo, Thuy Tran, Shailja C. Shah, John M. Inadomi, David A. Greenwald, Joo Ha Hwang Source Type: research

Serum fibrosis tests guide prognosis in metabolic dysfunction associated fatty liver disease patients referred from primary care
We examined the accuracy of non-invasive tests (NITs) as screening tools for the prediction of outcomes in MAFLD patients referred from primary care. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 5, 2021 Category: Gastroenterology Authors: Zhengyi Wang, Luis Calzadilla Bertot, Gary P. Jeffrey, John Joseph, George Garas, Bastiaan de Boer, Yi Huang, Gerry MacQuillan, Michael Wallace, Briohny Smith, Leon A. Adams Source Type: research

Gastric intramural abscess caused by a blister pack
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - October 5, 2021 Category: Gastroenterology Authors: Tomohiko Fukunaga, Yumi Somatomo, Toshihiko Kasanami Tags: Image of the Month Source Type: research