Clinical Utility of Magnetic Resonance Imaging Biomarkers for Identifying Nonalcoholic Steatohepatitis Patients at High Risk of Progression: A Multicenter Pooled Data and Meta-Analysis

Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide. NAFLD is associated with excess risk of all-cause mortality, and its progression to nonalcoholic steatohepatitis (NASH) and fibrosis accounts for a growing proportion of cirrhosis and hepatocellular cancer and thus is a leading cause of liver transplant worldwide. Noninvasive precise methods to identify patients with NASH and NASH with significant disease activity and fibrosis are crucial when the disease is still modifiable.

Source: Clinical Gastroenterology and Hepatology - October 6, 2021 Category: Gastroenterology Authors: Anneli Andersson, Matt Kelly, Kento Imajo, Atsushi Nakajima, Jonathan A. Fallowfield, Gideon Hirschfield, Michael Pavlides, Arun J. Sanyal, Mazen Noureddin, Rajarshi Banerjee, Andrea Dennis, Stephen Harrison Source Type: research