Effectiveness of Reinduction and/or Dose Escalation of Ustekinumab in Crohn ’s Disease: A Systematic Review and Meta-analysis

Patients with Crohn ’s disease (CD) treated with ustekinumab who experience inadequate response, or loss of response after standard induction and/or maintenance dosing may benefit from dose escalation. We conducted a systematic review and meta-analysis examining the effectiveness of reinduction and/or dose interval s hortening of ustekinumab in patients with active CD despite standard induction and maintenance.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research