TCGA study reveals new clues to the genomic diversity of prostate cancer
New findings on prostate cancer may enable doctors to make better diagnoses and prognoses for patients and provide novel directions for therapies, according to a new study from The Cancer Genome Atlas (TCGA) Network. Investigators published the in-depth analysis of 333 prostate cancer tumors online November 5, 2015 in Cell. TCGA is jointly supported and managed by the National Human Genome Research Institute and the National Cancer Institute, both parts of the National Institutes of Health. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - November 3, 2015 Category: Genetics & Stem Cells Source Type: news
The 1000 Genomes Project
In this month's The Genomics Landscape, I highlight the 1000 Genomes Project, which came to a close last month. At its conclusion, the 1000 Genomes Project cataloged more than 99 percent of all common - and many rare - human genomic variants. In November we also celebrate National Family History Day on Thanksgiving, a tradition at NHGRI and for the U.S. Surgeon General, and welcome a new investigator to NHGRI's intramural program. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - November 3, 2015 Category: Genetics & Stem Cells Source Type: news
Women with inherited breast cancer risk face numerous challenges
September's Genome Advance of the Month spotlights a Swiss study on women who are at increased risk for inherited breast cancer and the long term challenges they face in managing their care. It also identifies some of the challenges of providing care to at-risk individuals and highlights opportunities for improved models of care. The study is published in Genetics in Medicine. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 30, 2015 Category: Genetics & Stem Cells Source Type: news
HHS requests comments on proposal to update rules governing research on study participants
Medical advances wouldn't be possible without individuals willing to volunteer to participate in research. Proposed changes to the Common Rule for protecting human research participants would update safeguards for participants and reduce unnecessary administrative burdens. For more information and details on providing comments on the proposed rule, go to: (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 26, 2015 Category: Genetics & Stem Cells Source Type: news
Dr. John Ohab to lead NHGRI communications
Following a nationwide search, John Ohab, Ph.D., a neuroscientist and science communicator, has been named chief of the Communications and Public Liaison Branch (CPLB) at the National Human Genome Research Institute, part of the National Institutes of Health. In this role, he will oversee diverse communications activities about the institute's accomplishments, programs, goals and policies. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 16, 2015 Category: Genetics & Stem Cells Source Type: news
September Advisory Council Open Session
If you missed the 75th open session of the National Advisory Council for Human Genome Research (NACHGR), video is now available for the September 21st meeting held at Fishers Lane Conference Center. National Human Genome Research Institute Director Eric Green reported to council, followed by talks on Stevens-Johnson syndrome, precision medicine and the Genomics and Society Working Group. See it all at: (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 13, 2015 Category: Genetics & Stem Cells Source Type: news
TCGA team wins Sammies' People's Choice award
NHGRI's Carolyn Hutter and NCI's Jean Claude Zenklusen, along with the entire Cancer Genome Atlas team, have won the Samuel J. Heyman Service to America Medal People's Choice Award. The team mapped thousands of gene sequences for more than thirty types of cancer, advancing precision medicine in the diagnosis, treatment and prevention of these deadly diseases. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 8, 2015 Category: Genetics & Stem Cells Source Type: news
25th Anniversary of the Launch of the Human Genome Project
October's Genomics Landscape marks the 25th anniversary of the Human Genome Project launch, reflecting on how far genomics has progressed since 1990. Also this month, The Genomics Landscape celebrates its second birthday by continuing to provide noteworthy, interesting and vital genomics news. This issue highlights the Undiagnosed Diseases Network, genomic data sharing policy, functional variation grants, a new event for H3Africa and more. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - October 6, 2015 Category: Genetics & Stem Cells Source Type: news
Scientists create world's largest catalog of human genomic variation
An international team of scientists from the 1000 Genomes Project Consortium has created the world's largest catalog of genomic differences among humans, providing researchers powerful clues to why some people are susceptible to various diseases. Understanding how these differences - called genomic variants - contribute to disease may help clinicians develop improved diagnostics, treatments and prevention methods. The two studies are published online today, Sept. 30, in Nature. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 30, 2015 Category: Genetics & Stem Cells Source Type: news
Twenty-five Years of Big Biology
NHGRI Director Eric Green, M.D., Ph.D., reflects on the lasting legacy of the Human Genome Project 25 years after its start. Among HGP's far-reaching impacts: team science, data sharing and analysis, and technology development. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 30, 2015 Category: Genetics & Stem Cells Source Type: news
Gene-editing technology uncovers genetic link to infertility
Infertility - difficulty getting or staying pregnant - can come at a high financial and emotional cost, affecting about 6 million women and 4 million men in the United States. Half of these cases could be due to genetic factors. Now, new research techniques are yielding insight into the genetics of infertility. The August Genome Advance of the Month looks at a study in the Proceedings of the National Academy of Sciences that addresses the complex genetics of infertility using genetic sleuthing and cutting-edge, gene-editing technology. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 29, 2015 Category: Genetics & Stem Cells Source Type: news
Integrating Genomic Sequencing into Clinical Care: CSER and Beyond
On September 28, 2015, NHGRI will sponsor Integrating Genomic Sequencing into Clinical Care: CSER and Beyond at the DoubleTree Hilton in Bethesda, Md. The meeting's objectives will address the scientific contributions of the Clinical Sequencing Exploratory Research (CSER) Program, discuss integration of genomic sequencing into clinical care and identify the framework of a potential follow-up program. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 25, 2015 Category: Genetics & Stem Cells Source Type: news
NHGRI researchers to present talks, posters at ASHG annual meeting
National Human Genome Research Institute researchers will present four platform talks and 55 posters to highlight the institute's diverse portfolio at the 65th annual meeting of the American Society of Human Genetics. More than 6,500 scientific attendees and 200 exhibitors are expected to attend the meeting from October 6-10, held this year at The Baltimore Convention Center. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 22, 2015 Category: Genetics & Stem Cells Source Type: news
Undiagnosed Diseases Network launches online application portal
The Undiagnosed Diseases Network (UDN), a clinical research initiative of the National Institutes of Health, has opened an online patient application portal called the UDN Gateway. Introduction of this application system sets the stage for the network to advance its core mission: to diagnose patients who suffer from conditions that even skilled physicians have been unable to diagnose despite extensive clinical investigation. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 16, 2015 Category: Genetics & Stem Cells Source Type: news
TCGA team a finalist for Sammies, People's Choice awards
The Cancer Genome Atlas (TCGA) team has mapped thousands of genomes for more than thirty types of cancer to improve the ability to diagnose, treat and prevent cancer. Led by NHGRI's Carolyn Hutter and NCI's Jean Claude Zenklusen, the TCGA team is not only a finalist for the Samuel J. Heyman Service to America Medals award (the "Sammies"), a contender for the inaugural People's Choice Award. People's Choice voting closes at 11:59 p.m. Eastern, Sept. 30, 2015. For more information about the Sammies and to vote, visit (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - September 15, 2015 Category: Genetics & Stem Cells Source Type: news
