NIH awards $55 million to build million-person precision medicine study
The National Institutes of Health has announced $55 million in awards in 2016 to help launch the Cohort Program of President Obama's Precision Medicine Initiative (PMI). The Cohort Program is a long-term research effort to improve disease prevention and treatment in at least 1 million U.S. participants based on individual differences in lifestyle, environment and genetics. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - July 7, 2016 Category: Genetics & Stem Cells Source Type: news
The Power of Model Organisms for Studying Rare Diseases
In this issue of The Genomics Landscape, we feature the use of model organisms to explore the function of genes implicated in human disease. This month's issue also highlights a recently completed webinar series to help professionals in the health insurance industry understand genetic testing, new funding for training in genomic medicine research, and NHGRI's Genome Statute and Legislation Database. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - July 5, 2016 Category: Genetics & Stem Cells Source Type: news
New training grants prime doctors to tackle genomic medicine
The practice of medicine is expensive and doesn't fit in a one-hour time frame. Tests can only eliminate one diagnosis at a time. Questioning and family history can help a doctor arrive at the correct diagnosis, but even with the information gathered upfront, there are a huge number of tests to consider, and many tests may still be needed. Training doctors to use genomic sequencing is a powerful solution to the challenges facing today's medical practice. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 29, 2016 Category: Genetics & Stem Cells Source Type: news
One little fish hooks genome researchers with its versatility
Modern molecular biology and the genome of a tiny silver and black striped fish - the zebrafish - are making waves in genomics research. This tiny fish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease. Here, at the National Human Genome Research Institute (NHGRI), researchers are working to advance human health by coupling the potential of this little fish with an institute-funded resource known as The Zebrafish Core. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 29, 2016 Category: Genetics & Stem Cells Source Type: news
GHB chief joins Roundtable on Genomics and Precision Health
(Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 16, 2016 Category: Genetics & Stem Cells Source Type: news
Investigational Device Exemptions (IDE) and Genomics Workshop
Watch live on Friday, June 10, 2016, when the National Human Genome Research Institute (NHGRI) will host the Investigational Device Exemptions (IDE) and Genomics Workshop. The workshop will bring together perspectives from investigators, institutional review boards (IRB), the FDA and NHGRI on how to determine if a study requires an IDE, and how to fulfill IDE requirements if the FDA should require an IDE for research involving the use of genomic technologies, including next-generation sequencing (NGS). (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 9, 2016 Category: Genetics & Stem Cells Source Type: news
New NIH studies seek adults and families affected by sickle cell disease/trait
People with sickle cell disease (SCD) can experience excruciating pain, kidney problems, a higher risk of stroke and, in rare cases, chronic leg ulcers. Little is known about why the severity of these symptoms varies throughout a lifetime or why these symptoms differ from person to person. NHGRI researchers are seeking help from people affected by SCD to find the factors - environmental, social and genetic - that impact the severity of the symptoms. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 9, 2016 Category: Genetics & Stem Cells Source Type: news
Clinical Sequencing: Beyond Exploration
The Genomics Landscape for June features exciting developments with NHGRI's Clinical Sequencing Exploratory Research Program. We also highlight the new director of the National Library of Medicine, recently funded studies on the ethical, legal and social implications of genomic information, the final seminar commemorating the 25th anniversary of the launch of the Human Genome Project and available online videos for our lectures on genome analysis. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 7, 2016 Category: Genetics & Stem Cells Source Type: news
Bacterial toxins make the body go boom
By outward appearances, plants and animals don't seem to have much in common. When it comes to their immune systems, however, they might be more similar than their exteriors suggest. Researchers at the National Human Genome Research Institute have discovered an immune mechanism in humans, known as a "guard" mechanism, which was once thought to exist only in plants. They've published their results in the June 6 online journal Nature Immunology. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - June 2, 2016 Category: Genetics & Stem Cells Source Type: news
Perspective: Precision medicine may move us beyond the use of race in prescribing drugs
Health care providers have long struggled with considering race when prescribing and dosing medications. In a May 26 New England Journal of Medicine perspective, Vence L. Bonham, J.D., an investigator with NHGRI's Social and Behavioral Research Branch, and his colleagues, are asking if the precision medicine approach will reduce or eliminate the role that race plays in prescribing drugs and in health care overall. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 23, 2016 Category: Genetics & Stem Cells Source Type: news
A Quarter Century after the Human Genome Project's Launch presents: Dr. David Bentley
On Thursday, May 26th, the NHGRI History of Genomics Program will complete its six-part seminar series featuring Human Genome Project (HGP) scientists who helped launch the HGP. David Bentley, D.Phil., vice president and chief scientist for Illumina, will be the featured speaker. Prior to joining Illumina, while at the Wellcome Trust Sanger Institute, Dr. Bentley was a driving force behind the institute's immense contributions to the Human Genome Project. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 23, 2016 Category: Genetics & Stem Cells Source Type: news
Mouse models of Zika in pregnancy show how fetuses become infected
A new mouse model of Zika virus infection in pregnancy is offering clues about how the virus works. Researchers at Washington University School of Medicine in St. Louis showed that the virus migrated from the pregnant mouse's bloodstream into the placenta, eventually infecting, and causing cell death, in the brains of the unborn pups. Using this mouse model, researchers hope to learn about the virus' biology and develop new vaccines and treatments. The research, co-funded by NHGRI, appears in Cell. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 13, 2016 Category: Genetics & Stem Cells Source Type: news
NHGRI's advisory council to meet in open session
The open session for the seventy-seventh meeting of the National Advisory Council for Human Genome Research will meet meet Monday, May 16th, at the Fishers Lane Conference Center. NHGRI Director Eric Green, M.D., Ph.D., will report to council, followed by a talk from the new National Institute of Minority Health and Health Disparities director, (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 9, 2016 Category: Genetics & Stem Cells Source Type: news
Quantifying the benefits and risks of psychostimulant medication for ADHD
Establishing the benefits and possible risks of psychostimulant medication as a treatment for childhood Attention Deficit Hyperactivity Disorder (ADHD) is vital, says Philip Shaw, M.D., Ph.D., a researcher with NHGRI's Social and Behavioral Research Branch. His review of a recent meta-analysis on the use of the psychostimulant methylphenidate for ADHD appeared in the Journal of the American Medical Association (JAMA) and is the subject of a (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 9, 2016 Category: Genetics & Stem Cells Source Type: news
The Center for Inherited Disease Research at Twenty
For this issue of The Genomics Landscape, I am delighted to feature the Center for Inherited Disease Research, which was founded in 1996. This month's issue also highlights the USA Science and Engineering festival, the Undiagnosed Diseases Network, a new online atlas of human malformation syndromes in diverse populations, and a recent virtual scientific meeting. (Source: NHGRI Homepage Highlights)
Source: NHGRI Homepage Highlights - May 9, 2016 Category: Genetics & Stem Cells Source Type: news
