‘Obesity paradox’ holds true in COPD
Obese patients with chronic obstructive pulmonary disease are significantly less likely to die in hospital, or to be readmitted following an exacerbation than normal weight patients, show the results of Spanish research. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 16, 2013 Category: Respiratory Medicine Source Type: news

GOLD adherence raises costs in stage III COPD
Results of Spanish research show that adherence to the Global Initiative for Chronic Lung Disease guidelines reduces overall costs in the treatment of stage II chronic obstructive pulmonary disease, but not in stage III disease. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 15, 2013 Category: Respiratory Medicine Source Type: news

COPD clinicians urged not to ignore allergies
US research shows that patients with chronic obstructive pulmonary disease who have allergic symptoms or allergic sensitization experience more symptoms and exacerbations than those who do not. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 14, 2013 Category: Respiratory Medicine Source Type: news

Asthma symptoms ‘overestimated’ in obese children
Obese children with asthma may be overtreated, say US researchers who found that impaired mechanics of the chest, and not asthma itself, are responsible for some of the symptoms these patients experience. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 13, 2013 Category: Respiratory Medicine Source Type: news

Being young, free, and single no boost in COPD
Research shows that patients with alpha-1 antitrypsin deficiency-related chronic obstructive pulmonary disease experience more anxiety the younger they are. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 11, 2013 Category: Respiratory Medicine Source Type: news

GOLD guidance adherence remains low in COPD
A US study has found that nearly half of all patients with stable chronic obstructive pulmonary disease do not receive treatment in accordance with Global Initiative for Chronic Obstructive Lung Disease guidelines. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 9, 2013 Category: Respiratory Medicine Source Type: news

Gene variants linked to childhood acetaminophen–asthma risk
Researchers have found several gene polymorphisms that are associated with an increased risk for childhood asthma after acetaminophen consumption in early life. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

Burden of symptoms could guide NSCLC pemetrexed use
Symptom burden and performance status may help identify the patients with non-squamous non-small-cell lung cancer who are likely to respond to maintenance pemetrexed therapy, phase III trial findings suggest. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

KRAS oncogene substitutions may be predictive in lung adenocarcinoma
Researchers have found that certain KRAS oncogene substitutions may have predictive value in lung adenocarcinoma. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

TKI resistance markers found for NSCLC patients
Korean scientists have identified several genetic markers that may explain lack of response to tyrosine kinase inhibitor therapy in patients with epidermal growth factor receptor-activating, non-small-cell lung cancer. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

Hsp90 inhibitor shows NSCLC promise
Treatment with a heatshock protein 90 inhibitor may induce loss of EML4-AKL expression in non-small cell lung cancer cells, preliminary results suggest. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

Gene fusion reduces NSCLC patient survival
ROS1 fusions predict a poor outcome in Chinese patients with non-small-cell lung cancer, study findings suggest. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

S-1 combination regimen effective for NSCLC
Researchers suggest that combined therapy with the fluoropyrimidine S-1, carboplatin, and bevacizumab followed by maintenance therapy with S-1 and bevacizumab should be first-line treatment for patients with advanced non-squamous non-small-cell lung cancer. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

Thalidomide fails to boost mesothelioma outcomes
Adding maintenance thalidomide to standard first-line chemotherapy does not improve outcomes among patients with malignant pleural or peritoneal mesothelioma, study findings indicate. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 8, 2013 Category: Respiratory Medicine Source Type: news

Oxidant linked to COPD outcomes
Research shows that levels of serum myeloperoxidase are associated with rapid lung function decline and cardiovascular mortality in patients with chronic obstructive pulmonary disease. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 7, 2013 Category: Respiratory Medicine Source Type: news