KRAS mutation fails to predict NSCLC chemotherapy success
Research casts doubt on the ability of the KRAS mutation to aid the selection of patients with non-small-cell lung cancer to receive adjuvant chemotherapy. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 3, 2013 Category: Respiratory Medicine Source Type: news
Primary NSCLC shares mutations with metastases
Scientists have found a high level of concordance in the genetic mutations of pairs of primary non-small-cell lung cancer and metachronous or synchronous metastases. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 3, 2013 Category: Respiratory Medicine Source Type: news
COPD, comorbidities linked to poor hospitalization outcomes
Data from the Swiss population show that patients with chronic obstructive pulmonary disease who are hospitalized experience poorer outcomes than patients without COPD, even if the condition was not the reason they were admitted. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 31, 2013 Category: Respiratory Medicine Source Type: news
Selective ALK inhibitor shows NSCLC promise
Preliminary trial results suggest that a novel, highly selective ALK inhibitor may be effective for the treatment of advanced non-small-cell lung cancer in Japanese patients with the ALK rearrangement. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 30, 2013 Category: Respiratory Medicine Source Type: news
Late radiotherapy ‘not inferior’ for patients
Researchers have questioned the timing of thoracic radiotherapy for patients undergoing four cycles of chemotherapy for limited-disease small-cell lung cancer. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 30, 2013 Category: Respiratory Medicine Source Type: news
nab-paclitaxel promising for Japanese NSCLC patients
Phase III trial results support the use of albumin-bound paclitaxel plus carboplatin as a first-line treatment for Japanese patients with advanced non-small-cell lung cancer. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 30, 2013 Category: Respiratory Medicine Source Type: news
Community pharmacists help optimize COPD treatment
Data from Japan show that the introduction of an educational program allowing community pharmacists to deliver inhaler technique training to patients with chronic obstructive pulmonary disease led to improved adherence and outcomes. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 30, 2013 Category: Respiratory Medicine Source Type: news
Surrogate biomarkers unable to predict asthma severity
A study evaluating surrogate biomarkers of airway inflammation has failed to identify any that can predict sputum eosinophil and neutrophil percentages with sufficient accuracy in patients with asthma. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 29, 2013 Category: Respiratory Medicine Source Type: news
New Samter’s syndrome classification proposed
Turkish researchers have developed a classification system for patients with hypersensitivity to non-steroidal anti-inflammatory drugs. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 28, 2013 Category: Respiratory Medicine Source Type: news
Vitamin D ‘could enhance asthma control’
In vitro study results show that the active form of vitamin D can reduce the production of the pro-inflammatory cytokine interleukin-17A in both steroid-resistant and steroid-responsive patients with asthma. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 27, 2013 Category: Respiratory Medicine Source Type: news
Peripheral airway disease present even in mild asthma
Researchers have found that the alveolar component of exhaled nitric oxide is associated with lack of asthma control in patients with mild, untreated asthma. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 25, 2013 Category: Respiratory Medicine Source Type: news
Inflammatory markers associated with COPD–depression link
Two studies reported this week show that levels of pro-inflammatory cytokines are associated with both pulmonary function and depressive symptoms. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 22, 2013 Category: Respiratory Medicine Source Type: news
COPD bronchodilator cardiovascular risks comparable
The risk for cardiovascular events among older patients with chronic obstructive pulmonary disease is similar if they begin treatment with long-acting ß-agonists or muscarinic antagonists, show results from a large, population-based study. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 21, 2013 Category: Respiratory Medicine Source Type: news
Greater COPD guideline awareness needed in primary care
US study results show that primary care management of chronic obstructive pulmonary disease rarely conforms to the Global Initiative for Chronic Obstructive Lung Disease guidelines. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 20, 2013 Category: Respiratory Medicine Source Type: news
Questionnaire improves allergic rhinitis detection in asthma
Researchers have shown that the Self Assessment of Allergic Rhinitis and Asthma questionnaire is effective in identifying undiagnosed allergic rhinitis among asthma patients. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - May 17, 2013 Category: Respiratory Medicine Source Type: news
