Influenza–pneumonia epidemiologic puzzle solved
Influenza has a very strong but transient effect on the risk for Streptococcus pneumoniae infection, increasing susceptibility by a remarkable 100-fold – but only in the week following infection, research shows. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - July 1, 2013 Category: Respiratory Medicine Source Type: news

NSCLC immunization ‘proof of concept’ achieved
Immunization against MAGE-A3 is a feasible adjuvant treatment in patients with resectable non-small-cell lung cancer expressing the tumor-specific antigen, research suggests. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - July 1, 2013 Category: Respiratory Medicine Source Type: news

Protein expression could guide NSCLC chemotherapy choice
Protein expression analysis is technically possible as a means of guiding chemotherapy decisions in patients with a new diagnosis of advanced non-small-cell lung cancer, US investigators say. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - July 1, 2013 Category: Respiratory Medicine Source Type: news

Genetic testing could predict asthma persistence
Research suggests that genetic risk assessment could be used to predict whether a child’s asthma will persist into adulthood. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 30, 2013 Category: Respiratory Medicine Source Type: news

DOSE excels in predicting COPD exacerbations
Research shows that the DOSE index outperforms both the BODE and ADO indices in predicting future exacerbations of chronic obstructive pulmonary disease in Japanese patients. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 27, 2013 Category: Respiratory Medicine Source Type: news

Sit-to-stand test validated in COPD
Researchers have shown that the 5-repetition sit-to-stand test is valid and reliable in chronic obstructive pulmonary disease, and could therefore provide a more practical alternative to tests such as the 6-minute walk test or incremental shuttle walk test for measuring functional outcomes. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 26, 2013 Category: Respiratory Medicine Source Type: news

Spirometry essential for asthma diagnosis in morbidly obese
Researchers say that pulmonary function testing must be performed in morbidly obese patients to confirm a diagnosis of asthma after they found a high prevalence of, not only overdiagnosis but, underdiagnosis among such patients. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 25, 2013 Category: Respiratory Medicine Source Type: news

Oral hygiene boost could reduce elderly pneumonia risk
Findings from a US study suggest that improving oral hygiene could reduce rates of pneumonia in community-dwelling older adults. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 24, 2013 Category: Respiratory Medicine Source Type: news

Cochrane: more evidence needed for NIPPV in stable COPD
The authors of a Cochrane systematic review say that they have failed to find evidence of a consistent beneficial effect of non-invasive positive pressure ventilation in hypercapnic patients with chronic obstructive pulmonary disease. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 24, 2013 Category: Respiratory Medicine Source Type: news

Recession has second-hand consequences for children with asthma
Data from the US recession period suggest that during times of economic hardship, unemployment becomes a stronger determinant of smoking by parents of children with asthma. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 21, 2013 Category: Respiratory Medicine Source Type: news

Pulmonary effects leave cardiac red herring in COPD, emphysema
US researchers have found evidence that impaired left ventricular filling in patients with chronic obstructive pulmonary disease and emphysema is caused by reduced left ventricular preload due to upstream pulmonary causes, as opposed to intrinsic diastolic dysfunction. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 20, 2013 Category: Respiratory Medicine Source Type: news

High-dose steroids for COPD raise diabetes complication risk
Australian research shows that in older patients with chronic obstructive pulmonary disease and comorbid diabetes, high-dose corticosteroids are associated with an increased risk for diabetes-related complications, regardless of how they are administered. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 19, 2013 Category: Respiratory Medicine Source Type: news

Vitamin C improves post-exercise bronchoconstriction
Vitamin C can help alleviate exercise-induced bronchoconstriction, show the results of a meta-analysis published in BMJ Open. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 18, 2013 Category: Respiratory Medicine Source Type: news

Early asthma link to ADHD
Children who develop asthma early in life have a significantly increased risk for attention-deficit/hyperactivity disorder later in childhood, show the results of a nationwide, prospective study. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 17, 2013 Category: Respiratory Medicine Source Type: news

Neutrophil protease may increase bacterial susceptibility in COPD
Researchers have found that a protease released by neutrophils degrades a protective airway protein, which could lead to reduced airway defense to bacterial infection and increased risk for acute exacerbations in chronic obstructive pulmonary disease. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - June 17, 2013 Category: Respiratory Medicine Source Type: news