AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

FDA Publishes Final Guidance for Industry/Vaginal Microbicides: Development for the Prevention of HIV Infection
"The guidance provides the FDA's current thinking for development of vaginal microbicides for the prevention of human immunodeficiency virus (HIV) infection. The final guidance supersedes the 2012 draft guidance and incorporates the FDA’s responses to public comments submitted to the Agency.   "The guidance addresses issues related to nonclinical development, early phases of clinical development, phase 3 trial considerations, and safety considerations in vaginal microbicide development, including safety considerations in adolescent and pregnant populations."   For more information, read the FDA press releas...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - November 21, 2014 Category: Infectious Diseases Source Type: news

NIH-Sponsored Study Identifies Superior Drug Regimen for Preventing Mother-to-Child HIV Transmission
"For HIV-infected women in good immune health, taking a three-drug regimen during pregnancy prevents mother-to-child HIV transmission more effectively than taking one drug during pregnancy, another during labor and two more after giving birth, an international clinical trial has found.   "The ongoing PROMISE (Promoting Maternal-Infant Survival Everywhere) study also has found that one triple-drug regimen for preventing mother-to-child transmission may be safer than another for women and their babies."   For more information, read the NIH press release. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AI...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - November 21, 2014 Category: Infectious Diseases Source Type: news

Revised Hepatitis C (HCV)/HIV Coinfection Section of the Adult and Adolescent Antiretroviral Treatment Guidelines Released
The HHS Panel on Antiretroviral Guidelines for Adults and Adolescents announces the release of the updated Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. As described in What's New in the Guidelines, this interim revision of the guidelines features a revised section on Hepatitis C (HCV)/HIV Coinfection that emphasizes considerations for use of antiretroviral (ARV) drugs in patients who also receive treatment for HCV infection. The section includes a new table (Table 12) that provides clinicians with guidance on the concomitant use of HCV drugs and ARV drugs with a focus on po...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - November 13, 2014 Category: Infectious Diseases Source Type: news

News from NIAID
November 3, 2014: NIH Trial Tests Very Early Anti-HIV Therapy in HIV-Infected Newborns   October 30, 2014: Model by NIH Grantees Explains Why HIV Prevention Dosing Differs by Sex   October 28, 2014: In South Africa, RV144 HIV Vaccine Regimen Induces Immune Responses Similar to Those Seen in Thailand   October 28, 2014: NIH-Led Study Explores Prevention of Heart Disease in HIV-Infected People (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - November 7, 2014 Category: Infectious Diseases Source Type: news

Updates to Adult and Adolescent Opportunistic Infections Guidelines Released
Updates to the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents were released on October 28, 2014. The updates affect the following sections: Pneumocystis Pneumonia  Bacterial Enteric Infections Mucocutaneous Candidiasis  Hepatitis C Virus Infection Table: Prophylaxis to Prevent First Episode of Opportunistic Disease  Table: Treatment of AIDS-Associated Opportunistic Infections  Table: Opportunistic Infection Drugs in Pregnancy  For a summary of the major updates, please see What’s New in the Guidelin...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - November 7, 2014 Category: Infectious Diseases Source Type: news

View AIDSinfo Patient Fact Sheets on Three Recently Approved HIV Medications
AIDSinfo invites you to view our patient fact sheets on three medications recently approved by the FDA. The three medications are all indicated for use in the treatment of HIV infection in adults. The patient fact sheets include information on dosage forms and strengths, possible side effects, and instructions on how to take and store the medications. Fact sheet on abacavir/dolutegravir/lamivudine (brand name: Triumeq) Triumeq is a combination medicine that can be used alone as a complete treatment regimen or with other HIV medicines. Fact sheet on cobicistat (brand name: Tybost) Cobicistat is ...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - October 24, 2014 Category: Infectious Diseases Source Type: news

October 15 is National Latino AIDS Awareness Day
National Latino AIDS Awareness Day is observed annually to highlight the disproportionate burden of HIV among Hispanics/Latinos. According to the Centers for Disease Control and Prevention (CDC), Hispanics/Latinos—despite representing only 16% of the U.S. population—accounted for 21% of new HIV infections in 2010. Explore our National Latino AIDS Awareness Day webpage [en español] to learn more about the annual observance and to find information about HIV in the Hispanic/Latino population. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of t...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - October 10, 2014 Category: Infectious Diseases Source Type: news

Newly Identified Marker Helps Predict Tuberculosis Complications in HIV Patients
"An NIAID study suggests that the increased frequency of an immune cell called CD14++CD16- monocyte is a strong indicator that a patient with HIV and tuberculosis (TB) may develop complications from anti-HIV drugs. For unclear reasons, a subset of people with both HIV and TB experience worsening of their TB symptoms after starting antiretroviral therapy (ART) to treat HIV. The study, which appears in the October 2, 2014, issue of PLOS Pathogens, offers a better understanding of why this may occur." Visit the NIAID website to read the complete article. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AI...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - October 10, 2014 Category: Infectious Diseases Source Type: news

NIH-Supported Scientists Unveil Structure, Dynamics of Key HIV Molecules
"New research has illuminated the movement and complete structure of the spikes on HIV that the virus uses to bind to the cells it infects. This research, led by scientists at the National Institutes of Health, Weill Cornell Medical College and Yale University School of Medicine, could help advance efforts to develop HIV vaccines and treatments." For more information, view the NIAID press release. (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - October 10, 2014 Category: Infectious Diseases Source Type: news

September 27 is National Gay Men’s HIV/AIDS Awareness Day
September 27 is the annual observance of National Gay Men’s HIV/AIDS Awareness Day, which serves to highlight the continuing impact of the HIV/AIDS epidemic among gay men. Gay and bisexual men are more severely affected by HIV than any other group in the United States. According to CDC, gay, bisexual, and other men who have sex with men (MSM) represent approximately 2% of the U.S. population but accounted for 63% of estimated new HIV infections in 2010. Explore our National Gay Men’s HIV/AIDS Awareness Day webpage [en español] to learn more about this observance and to find information on...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 26, 2014 Category: Infectious Diseases Source Type: news

CDC Launches HIV Treatment Works Campaign
CDC recently launched HIV Treatment Works, a new national campaign focused on encouraging people infected with HIV to get into care and adhere to treatment. The website includes information and resources for people living with HIV, including information on treatment adherence and tips for healthy living. Visit the HIV Treatment Works website to find an HIV care provider, an HIV support group, or mental health provider. For more information, view the CDC press release.  (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Departm...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 26, 2014 Category: Infectious Diseases Source Type: news

CDC Seeks Public Comments on Newly Developed Draft Clinical Quality Measure for HIV Screening
The Centers for Disease Control and Prevention (CDC) is seeking public comments on a newly developed draft clinical quality measure for HIV infection screening. The measure aligns with the U.S. Preventive Services Task Force (USPSTF) recommendations that all individuals between the ages of 15 and 65 be screened for HIV. The measure was developed in collaboration with clinicians and quality experts. The goal is to develop a measure that will be nationally endorsed through the National Quality Forum (NQF) and included in the Centers for Medicare and Medicaid Services (CMS) programs. Public comments will be accepted thr...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 26, 2014 Category: Infectious Diseases Source Type: news

FDA Approves Two Medications to Treat HIV Infection: Cobicistat (Brand Name: Tybost) and Elvitegravir (Brand Name: Vitekta)
"On September 24, 2014, FDA approved Tybost (cobicistat) 150 mg tablets. Tybost is a CYP3A inhibitor indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 infection." For more information on cobicistat, view the FDA press release. "On September 24, 2014, FDA approved Vitekta (elvitegravir) 85 mg and 150 mg tablets. Vitekta is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor indicated in combination with an HIV protease inhibitor coadministered with ritonavir an...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 26, 2014 Category: Infectious Diseases Source Type: news

NIH-Led Scientists Discover HIV Antibody that Binds to Novel Target on Virus
"An NIH-led team of scientists has discovered a new vulnerability in the armor of HIV that a vaccine, other preventive regimen or treatment could exploit. The site straddles two proteins, gp41 and gp120, that jut out of the virus and augments other known places where broadly neutralizing antibodies (bNAbs) bind to HIV. This newly identified site on the viral spike is where a new antibody found by the scientists in an HIV-infected person binds to the virus. Called 35O22, the antibody prevents 62 percent of known HIV strains from infecting cells in the laboratory and is extremely potent, meaning even a relatively small ...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 12, 2014 Category: Infectious Diseases Source Type: news

September 18 is National HIV/AIDS and Aging Awareness Day
National HIV/AIDS and Aging Awareness Day is a day set aside each year to recognize the impact of HIV/AIDS among older adults. According to the Centers for Disease Control and Prevention (CDC), adults aged 55 and older accounted for 19% of the estimated 1.1 million people living with HIV infection in the United States in 2010. Older Americans are more likely than younger Americans to be diagnosed with HIV infection late in the course of their disease, which may mean a later start to treatment, possibly causing more damage to their immune system. This can lead to poorer prognoses and shorter HIV-to-AIDS intervals. Vis...
Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS) - September 12, 2014 Category: Infectious Diseases Source Type: news