Veterinary Immunology and Immunopathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Intranasally administered polyethylenimine adjuvanted influenza M2 ectodomain induces partial protection against H9N2 influenza A virus infection in chickens
This study aimed to investigate whether intranasally coadministered four tandem copies of extracellular domains of M2 (M2e) and polyethyleneimine (PEI), a mucosal adjuvant, can protect chickens against H9N2 influenza A virus infection. Groups of chickens were intranasally vaccinated with M2e plus PEI adjuvant, M2e alone or PEI adjuvant, and antibody (serum IgG and mucosal IgA) and cellular (CD4+ T cells and IFN-γ levels) immune responses were measured post-vaccination. We demonstrated that the chickens vaccinated with M2e plus PEI adjuvant showed significantly (p < 0.05) higher M2e-specific systemic IgG and mucosa...
Source: Veterinary Immunology and Immunopathology - March 5, 2019 Category: Veterinary Research Source Type: research

Breed-specific variations in the coding region of toll-like receptor 4 in the domestic cat
Publication date: Available online 26 February 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): J. Whitney, B. Haase, J. Beatty, V.R. BarrsAbstractSpecific point mutations in the human toll-like receptor 4 (TLR4) confer altered risk for diverse diseases, including sepsis, aspergillosis and inflammatory bowel disease. Some of these TLR4 polymorphisms are racially specific. We hypothesised that feline TLR4 polymorphisms might underlie an observed increased risk to infectious and inflammatory diseases in some cat breeds. The aim of this study was to identify breed-specific variations in the coding region of fel...
Source: Veterinary Immunology and Immunopathology - February 27, 2019 Category: Veterinary Research Source Type: research

Docosahexaenoic acid and TUG-891 activate Free Fatty Acid-4 receptor in bovine neutrophils
Publication date: Available online 25 February 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Ivan Olmo, Stefanie Teuber, Camilo Larrazabal, Pablo Alarcon, Fernanda Raipane, Rafael A. Burgos, Maria A. HidalgoAbstractFatty acids are well known metabolic intermediaries but also have a role in the immune response. Long-chain fatty acids such as omega-6 and -9 activate neutrophil function through free fatty acid (FFA)-1 receptor in bovines. Although omega-3 has also been suggested to influence neutrophil function, the details remain unclear. The goal of this study was to determine the presence of the bovine FF...
Source: Veterinary Immunology and Immunopathology - February 26, 2019 Category: Veterinary Research Source Type: research

Expression profiling of selected miRNAs in equine endometrium in response to LPS challenge in vitro: a new understanding of the inflammatory immune response
Publication date: Available online 16 February 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Sally Ibrahim, Anna Szóstek-Mioduchowska, Dariusz SkarzynskiAbstractBacterial infections of the genital tract are the major cause of reproductive failure in the mares. MiRNAs are important regulators of gene expression, mostly through transcriptional and translational regression. We hypothesized that LPS induced aberrant expression of miRNAs and their targets, which are involved in regulation of uterine homeostasis. Three groups of primary endometrial epithelial and stromal cells, and endometrial tissue explants ...
Source: Veterinary Immunology and Immunopathology - February 17, 2019 Category: Veterinary Research Source Type: research

Attenuated Salmonella secreting Brucella protective antigens confer dual-faceted protection against brucellosis and salmonellosis in a mouse model
In conclusion, we show that the live attenuated Salmonella delivering Brucella protective antigens may efficiently confer dual protection against both brucellosis and salmonellosis in immunized mice. (Source: Veterinary Immunology and Immunopathology)
Source: Veterinary Immunology and Immunopathology - February 15, 2019 Category: Veterinary Research Source Type: research