From Research to Policy Implementation: Trastuzumab in Early-Stage Breast Cancer Treatment in Thailand
ConclusionsA combination therapy that includes trastuzumab is a preferable choice and should be used in early-stage breast cancer treatment. The Thai government has listed trastuzumab on the National List of Essential Medicines to be used for the early stages of breast cancer since 2014. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 12, 2018 Category: International Medicine & Public Health Source Type: research

Engagement in a Community Physical Activity Program and Its Effects Upon the Health-Related Quality of Life of Elderly People: A Cross-Sectional Study
ConclusionsThe SF-36 subscales were not sufficiently sensitive to detect differences between the S and PA groups (except for functioning capacity and general health perceptions), probably because of ceiling effects. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 11, 2018 Category: International Medicine & Public Health Source Type: research

Role of Health Technology Assessment in Drug Policies: Korea
Publication date: May 2019Source: Value in Health Regional Issues, Volume 18Author(s): Eun-Young BaeAbstractSouth Korea is the first Asian country to mandate the submission of pharmacoeconomic data for reimbursement decision making. For a new drug to be listed, it must demonstrate its value in terms of comparative effectiveness and cost effectiveness. The Health Insurance Review and Assessment Service (HIRA) judges the submitted drug’s value and decides whether its coverage is appropriate on the basis of the recommendation of the Pharmaceutical Benefit Coverage Assessment Committee. Once the drug has been accepted by HIR...
Source: Value in Health Regional Issues - November 11, 2018 Category: International Medicine & Public Health Source Type: research

Assessing the Burden of Type 2 Diabetes in China Considering the Current Status-Quo Management and Implications of Improved Management Using a Modeling Approach
ConclusionsImproved T2D management strategies can help to decrease the financial burden of the disease and increase life expectancy of individuals with T2D. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 11, 2018 Category: International Medicine & Public Health Source Type: research

Medication Adherence and Diabetes Self-Care Activities among Patients with Type 2 Diabetes Mellitus
ConclusionsThe Malaysians had a moderate medication adherence level, whereas they were nonadherent to blood glucose testing. Emphasis on self-care activities and medication adherence is relevant to improve outcomes in the management of T2DM. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 11, 2018 Category: International Medicine & Public Health Source Type: research

Cost Effectiveness of Combination Therapy Versus Monotherapy in Benign Prostatic Hyperplasia: A Colombian Experience
ConclusionsThe combination of finasteride and doxazosin is cost-effective compared with dutasteride, tamsulosin, terazosin, and alfuzosin in patients with benign prostatic hyperplasia with moderate or severe symptoms who are older than 40 years. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 9, 2018 Category: International Medicine & Public Health Source Type: research

Pharmaceutical Policy Reforms to Regulate Drug Prices in Asia Pacific Region: The Case of Australia, China, India, Malaysia, New Zealand, and South Korea
Publication date: May 2019Source: Value in Health Regional Issues, Volume 18Author(s): Syed Shahzad Hasan, Chia Siang Kow, Dalia Dawoud, Omneya Mohamed, Darrin Baines, Zaheer-Ud-Din BabarABSTRACTMedicine price directly affects affordability and access to medicines particularly in countries where a major portion of pharmaceutical spending is through out-of-pocket payment, such as in the Asia Pacific region. We have undertaken a detailed appraisal of the pharmaceutical policy reforms to regulate drug prices in 3 developed (Australia, New Zealand, and South Korea) and 3 emerging (China, India, and Malaysia) economies of the A...
Source: Value in Health Regional Issues - November 8, 2018 Category: International Medicine & Public Health Source Type: research

Economics of Medical Devices in India
Publication date: May 2019Source: Value in Health Regional Issues, Volume 18Author(s): Amit Dang, Jitendar Kumar SharmaABSTRACTMost of the industrial sectors of India have undergone major changes in the post-liberalization period. During this period, India has become self-reliant in drugs; however, still, 75% of the medical devices are imported in India. According to WHO, almost all devices present in the developing countries have been designed for use in the industrialized countries. With the increase in incidence of non-communicable diseases and decrease in communicable diseases; increase in survival rates and decrease i...
Source: Value in Health Regional Issues - November 8, 2018 Category: International Medicine & Public Health Source Type: research

A Trial-Based Cost-Effectiveness Analysis of Bevacizumab and Chemotherapy versus Chemotherapy Alone for Advanced Nonsquamous Non–Small-Cell Lung Cancer in China
ConclusionsBevacizumab is not cost-effective when combined with chemotherapy for patients with advanced nonsquamous NSCLC based on the Chinese health care system, resulting in a less demand in the Chinese market. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 8, 2018 Category: International Medicine & Public Health Source Type: research

Comparison of Equity Preferences for Life Expectancy Gains: A Discrete Choice Experiment among the Japanese and Korean General Public
ConclusionsPeople from the two Asian developed countries, with universal health insurance, show different equity preferences. These may reflect the variations in cultural background and coverage of health care services. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 8, 2018 Category: International Medicine & Public Health Source Type: research

Antirheumatic Medicine Prescribing Patterns and Direct Medicine Costs in the South African Private Health Sector
ConclusionsThe direct medicine treatment cost of RA in the South African private health sector is driven by the high volume of DMARDs and the high mean costs of biologics, particularly adalimumab. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - November 6, 2018 Category: International Medicine & Public Health Source Type: research

Indacaterol/Glycopyrronium versus Salmeterol/Fluticasone in Patients with COPD—A Cost-Effectiveness Analysis in the Czech Republic
ConclusionsFrom the perspective of the Czech health care system, managing COPD using IND/GLY is cost-effective in this analysis because the base-case is clearly below the willingness-to-pay threshold in the Czech Republic, which is automatically set at 3 times GDP/capita (approximately ζ44,000/ QALY). This is the first available economic analysis utilizing FLAME study results in the Central East European (CEE) countries showing IND/ GLY as a highly cost-effective investment into COPD patients. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - October 27, 2018 Category: International Medicine & Public Health Source Type: research

Cost-Effectiveness of rFVIIa versus pd-aPCC in the Management of Mild to Moderate Bleeds in Pediatric Patients with Hemophilia A with Inhibitors in Mexico
ConclusionAccounting for model uncertainty, rFVIIa provided cost savings over pd-aPCC for the Mexican public health care payer in the management of mild-to-moderate joint bleeds in pediatric hemophilia A with inhibitors. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - October 27, 2018 Category: International Medicine & Public Health Source Type: research

What Is a Value Management Office? An Implementation Experience in Latin America
Publication date: December 2018Source: Value in Health Regional Issues, Volume 17Author(s): Marcia Makdisse, Marcelo Katz, Pedro Ramos, Adriano Pereira, Sandra Shiramizo, Miguel Cendoroglo Neto, Sidney KlajnerAbstractValue-based health care has been touted as the “strategy that will fix healthcare,” yet putting this value agenda to work in the real world is not an easy task. Robert Kaplan and colleagues first introduced the concept of a value management office (VMO) that may help to accelerate the dissemination and adoption of this value agenda. In this article, we describe the first known experience of the implementat...
Source: Value in Health Regional Issues - October 27, 2018 Category: International Medicine & Public Health Source Type: research

Ingredientes Farmacéuticos Activos Potencialmente Inapropiados en Adultos Mayores: Lista IFAsPIAM: Panel de Consenso Argentino
ConclusionThis study presents the first Latin American list of PIM in OP developed using an expert consensus technique. The IFAs PIAM List would contribute to the rational use of drugs in elderly population, constituting a valuable tool in Argentinean public health. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - October 27, 2018 Category: International Medicine & Public Health Source Type: research