Cost of Healthcare Associated With Deep Vein Thrombosis in Patients Treated With Warfarin in Turkey: 2010-2013 Database Analysis of a Tertiary Care Center
ConclusionsOur findings for a retrospective cohort of patients with DVT undergoing warfarin therapy reveal that patients spent 70% or more, as opposed to less than 70%, of follow-up time within the therapeutic INR range and that outpatient care, as opposed to inpatient care, was associated with lower healthcare costs. Given the significant contribution that hospital stay makes to the cost burden of DVT, our findings also highlight the association between poor warfarin anticoagulant control and increased hospitalization costs. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - June 27, 2019 Category: International Medicine & Public Health Source Type: research

Costo de la intoxicación por Paraquat en Colombia
ConclusionsThe average cost per patient intoxicated by PQ exceeds that of various chronic diseases prevalent in our country. This reveals the impact not only clinical, but also economical, of this poisoning in our country, necessitating strategies that regulate commercialization to avoid premature deaths.Resumen en espaÑolIntroducciónLa intoxicación con paraquat en un problema global especialmente en países en vía de desarrollo. La falta de información respecto al impacto económico generado por dicha problemática en el país, constituye una barrera para la correcta asignación de recursos en salud.ObjetivoEstimar e...
Source: Value in Health Regional Issues - June 9, 2019 Category: International Medicine & Public Health Source Type: research

Valuing Health States in Russia: A First Feasibility Study
ConclusionsRussia is commencing its health technology assessment journey and should proceed cautiously as it moves toward the valuation of health benefits. These results suggest a useful framework for a more in-depth development of health valuation methodologies in Russia. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - June 7, 2019 Category: International Medicine & Public Health Source Type: research

Custo-utilidade de terapias-alvo comparadas à dacarbazina para o tratamento de primeira linha do melanoma avançado não-cirúrgico e metastático no Sistema Único de Saúde do Brasil
ConclusionThe incorporation of targeted therapies in the Brazilian public health system would produce an additional expenditure of at least 19 times the national GDP per capita to increase in one year the quality-adjusted survival of each patient with advanced/metastatic BRAF-mutant melanoma.ResumoObjetivoEstimar a razão de custo-utilidade incremental (RCUI) de esquemas de terapias-alvo isoladas e combinadas em comparação à dacarbazina para o tratamento de primeira linha do melanoma avançado não-cirúrgico e metastático com mutação no gene BRAF V600.MétodosUm modelo de Markov com três estados de saúde (sem prog...
Source: Value in Health Regional Issues - June 5, 2019 Category: International Medicine & Public Health Source Type: research

What Is the Value of Innovative Pharmaceutical Therapies in Oncology and Hematology? A Willingness-to-Pay Study in Bulgaria
ConclusionsWe found a high willingness-to-pay for innovative drugs in oncology and hematology. The wide range of responses observed, however, indirectly implies a lack of consensus on the use of explicit ICER thresholds in Bulgaria. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 18, 2019 Category: International Medicine & Public Health Source Type: research

Effectiveness and Cost-Effectiveness of Triple Therapy with Telaprevir and Boceprevir for Chronic Hepatitis C: A Decision Analysis from the Brazilian Public Health System Perspective
ConclusionsTelaprevir is more effective and cost-effective than boceprevir. Our model may be applied for other settings with a few adjustments in the input parameters. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 18, 2019 Category: International Medicine & Public Health Source Type: research

Cost-Effectiveness of Secukinumab Versus Other Biologics in the Treatment of Psoriatic Arthritis: An Argentinean Perspective
ConclusionsFor both biologic-naïve and experienced PsA patients, secukinumab is either a dominant or cost-effective treatment option compared with other biologics in Argentina. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 17, 2019 Category: International Medicine & Public Health Source Type: research

Cost-Effectiveness of Docetaxel and Paclitaxel for Adjuvant Treatment of Early Breast Cancer: Adaptation of a Model-Based Economic Evaluation From the United Kingdom to South Africa
ConclusionsBased on the adapted model, docetaxel and paclitaxel are predicted to be cost-effective as adjuvant treatment for early breast cancer in South Africa. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 15, 2019 Category: International Medicine & Public Health Source Type: research

Requirements for a Successful Drug Launch in Small Markets: A Pilot Study in Lebanon
ConclusionsMajor challenges facing pharmaceutical companies under Lebanon's uncertain environment did not hinder companies from bringing innovative products. A partnership among decision makers, consumers, and pharmaceutical companies is the most efficient method to ensure future access to new and innovative drugs. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 11, 2019 Category: International Medicine & Public Health Source Type: research

Cost-Effectiveness of Bariatric Surgery Compared With Nonsurgical Treatment in People With Obesity and Comorbidity in Colombia
ConclusionThe current study provides evidence that bariatric surgery is a cost-effective alternative among some cohorts in the Colombian setting. For obese patients with sleep apnea or diabetes, bariatric surgery is a recommendable alternative (dominant and cost-effective, respectively) for the Colombian healthcare system. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - May 11, 2019 Category: International Medicine & Public Health Source Type: research

Budgetary Impact of Oral Rehabilitation with Complete Dentures: An Economical Evaluation from São Paulo State, Brazil
ConclusionThe budgetary impact of increasing the oral rehabilitation with complete dentures for elderly population in the São Paulo state is low relative to the expenses with primary or specialized care budgets. In addition, incorporation of denture rehabilitation would be feasible, according to the financial availability and priorities of each municipality. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - April 30, 2019 Category: International Medicine & Public Health Source Type: research

Burden of Disease Attributable to Obesity and Overweight in Colombia
ConclusionsObesity and overweight conditions are related to higher mortality and disability than previously estimated; effective interventions aimed at prevention and treatment will have a high impact on quality of life. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - April 29, 2019 Category: International Medicine & Public Health Source Type: research

Safety-Engineered Syringes: An Intervention to Decrease Hepatitis C Burden in Developing Countries—A Cost-Effectiveness Analysis from Egypt
ConclusionsAdoption of SES in the Egyptian healthcare settings is a more effective and cost-saving strategy. Our results are consistent with the WHO Injection Safety Program and Safe Injection Global Network initiatives, which call for adoption of smart syringes. The introduction of SES as one of the most urgently needed interventions is mostly encouraged to decrease hepatitis C burden in similar resource-limited settings. The use of SES as a prevention strategy may bring substantial population-level health gains and governmental cost savings in developing countries. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - April 17, 2019 Category: International Medicine & Public Health Source Type: research

The Public Health Benefits and Economic Value of Routine Yellow Fever Vaccination in Colombia
ConclusionsRoutine toddler YF vaccination in Colombia would have been considered cost-effective in the prevaccination era. This study provides insights on the value of vaccination in an upper middle-income country. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - April 9, 2019 Category: International Medicine & Public Health Source Type: research

Impact of a Collaborative Pharmaceutical Care Service Among Patients With Diabetes in an Ambulatory Care Setting in Qatar: A Multiple Time Series Study
ConclusionsCPCS provision improves clinical outcomes in patients with diabetes over a 12-month follow-up period in a primary healthcare setting. Future studies should determine the long-term impact of a collaborative care model in this setting. (Source: Value in Health Regional Issues)
Source: Value in Health Regional Issues - March 14, 2019 Category: International Medicine & Public Health Source Type: research