Skull metastasis in urothelial cell carcinoma of the bladder
We present a case of occipital bone metastasis arising from a previously verified bladder urothelial carcinoma. An 81-year-old woman presented with a painless, nonpulsatile mass in the left occipital region of the scalp that had progressively increased for 1 year. Skull radiography demonstrated a large osteolytic lesion in the left occipital bone. Computed tomography of the head showed a 6.5 cm × 6.0 cm skull defect from the midline to the left occipital bone, overlying the posterior superior sagittal sinus. The patient underwent a wide craniectomy with en bloc removal of the mass. Because of widespread disease, the p...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Tenofovir nephropathy in a patient with human immunodeficiency virus
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Wei-Shan Tsai, Lih-Shinn Wang, Yung-Hsiang Hsu, Yu-Li Lin, Te-Chao Fang, Bang-Gee Hsu Tenofovir is an effective and widely used antiretroviral drug for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus infection. Although large clinical studies and postmarketing data support a benign renal profile for tenofovir, numerous cases of kidney injury have raised concerns about its nephrotoxic potential. Here, we describe the case of a 33-year-old man with HIV who was treated with tenofovir, follow...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Surgical outcomes of a modified Marmot operation with transverse cutting of the spinal process in patients with degenerative lumbar spinal stenosis
Conclusions A microscope-assisted modified Marmot operation combined with spinal process transverse cutting laminectomy was an effective procedure for spinal decompression. As the procedure produces only unilateral muscular trauma, patients can ambulate early. Overall, the procedure is safe and effective. It provides good surgical field exposure and satisfactory neurological and functional outcomes. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Effects of tetrandrine and caffeine on cell viability and expression of mammalian target of rapamycin, phosphatase and tensin homolog, histone deacetylase 1, and histone acetyltransferase in glioma cells
Conclusion Tetrandrine and caffeine can increase glioma cell death additively possibly via increasing p300 expression. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

HLA-A*33-B*58:45-DRB1*03, a deduced probable human leukocyte antigen haplotype associated with a human leukocyte antigen low-incidence allele B*58:45 in Taiwanese unrelated hematopoietic bone marrow stem cell donors
Conclusion Information on this deduced probable HLA haplotype in association with the low-incidence B*58:45 allele is of value for HLA testing laboratories for reference purposes and can help bone marrow donor registries find compatible donors for patients with this uncommon HLA allele. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

C-type atriuretic peptide causes relaxation of the internal anal sphincter through natriuretic peptide receptor B
Conclusion CNP causes relaxation of the IAS via NPR-B, cGMP, and potassium channel pathways in rats. CNP might regulate IAS motility. NPR-B is a potential therapeutic target in anorectal motility disorders. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

The role of microRNAs in the proliferation, differentiation, invasion, and apoptosis of trophoblasts during the occurrence of preeclampsia—A systematic review
Conclusion Overall, miRNAs have been confirmed to be involved in the shallow invasion by trophoblasts into the spiral arteries and decidual stroma during early gestation and these miRNAs are possible promising biomarkers that may help to predict preeclampsia in the future. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Emerging diseases in Bangladesh: Current microbiological research perspective
Publication date: June 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 2 Author(s): Rashed Noor, Md. Sakil Munna Bangladesh has experienced a variety of diseases caused by natural dissemination of an array of pathogenic microorganisms into the environment. While cures for these diseases largely depend on the medication strategies of physicians, determining the reasons for disease persistence as well for the onset of reinfection is also essential. Routine diagnosis of common diseases usually means treatment with a range of appropriate medicines; however, failure of these medications because of the drug resista...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Dialysis catheter-related pulmonary embolism in a patient with paraquat intoxication
Publication date: Available online 2 July 2015 Source:Tzu Chi Medical Journal Author(s): Li-Keng Chao, Te-Chao Fang A 30-year-old woman was sent to the emergency room after alcohol and paraquat ingestion. After three sessions of hemoperfusion via the indwelling double-lumen catheter, the patient could tolerate ambient air and her urine output was good. However, on the 10th day of hospitalization, she had a sudden onset of dyspnea and hypoxia. Pulmonary embolism was diagnosed by a computed tomography pulmonary angiogram. The patient recovered after anticoagulation therapy. We could find no reports of dyspnea caused ...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

An unusual echocardiographic presentation of left atrial dissection following cardiopulmonary cerebral resuscitation
Publication date: Available online 8 July 2015 Source:Tzu Chi Medical Journal Author(s): Chia-Ling Lee, Yi-Tso Cheng, Ming-Chon Hsiung, Chen-Fuh Lam Left atrial dissection (LatD) is a relatively rare perioperative complication during mitral valve repair. Here, we report a 64-year-old man who developed LatD after cardiopulmonary resuscitation was needed due to an extensive myocardial infarction. Aggressive cardiac massage resulted in cardiac rupture and massive bloody pleura effusion. Intraoperative three-dimensional transesophageal echocardiography revealed posterior-medial papillary muscle ruptured and separat...
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

A blood clot hanging in the anterior chamber due to delayed suprachoroidal hemorrhage after trabeculectomy
We report a patient with hypertension who had DSCH following trabeculectomy, with an unusual presenting picture of a large blood clot hanging in a deep anterior chamber. Anterior chamber irrigation and choroidal taps were performed immediately. The intraocular pressure was soon controlled, and the visual acuity returned to 20/25 in 6 months. (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Use of extracorporeal removal techniques in patients with paraquat toxicity and unknown hepatitis viral marker status
Publication date: Available online 18 August 2015 Source:Tzu Chi Medical Journal Author(s): Sayed Mahdi Marashi, Hojatollah Raji, Zeynab Nasri-Nasrabadi, Mohammad Majidi (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Thoracic aortic aneurysm
Publication date: September 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 3 Author(s): Po-Yu Chang, Yin-Ming Li (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Pulmonary alveolar proteinosis
Publication date: September 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 3 Author(s): Cheng-Fa Chou, Wen-Chih Huang (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research

Mixed medullary and papillary carcinoma of the thyroid: A case report
Publication date: September 2015 Source:Tzu Chi Medical Journal, Volume 27, Issue 3 Author(s): Fang-Ping Kung, Chien-Chin Chen (Source: Tzu Chi Medical Journal)
Source: Tzu Chi Medical Journal - February 25, 2016 Category: Universities & Medical Training Source Type: research