Discrimination between respiratory and non-respiratory sound waveforms in dogs using acoustic wave recordings: An objective metric of cough
Publication date: Available online 20 September 2019Source: The Veterinary JournalAuthor(s): M. Grobman, T. Lever, C.R. ReineroAbstractCough is an important respiratory protective mechanism, which when persistent also contributes to disease pathology. It is therefore both a marker for and a target of therapeutic intervention. In dogs, assessment of cough is subjective, generally based on owner’s perceptions of clinical signs. In humans, acoustic cough monitoring provides objective data on cough frequency by examining acoustic waveforms. We hypothesized that healthy mesocephalic dogs would demonstrate characteristic cough...
Source: The Veterinary Journal - September 21, 2019 Category: Veterinary Research Source Type: research
ABCB1 c.-6-180T > G polymorphism and clinical risk factors in a multi-breed cohort of dogs with refractory idiopathic epilepsy
Publication date: November 2019Source: The Veterinary Journal, Volume 253Author(s): T. Gagliardo, G. Gandini, A. Gallucci, M. Menchetti, E. Bianchi, M.E. Turba, A. Cauduro, D.S. Corlazzoli, S. Gianni, M. Baroni, M. Bernardini, F. GentiliniAbstractEpilepsy is the most common chronic neurological disorder in dogs. Approximately 20–30% of dogs do not achieve satisfactory seizure control with two or more anti-epileptic drugs at appropriate dosages. This condition, defined as refractory epilepsy, is a multifactorial condition involving both acquired and genetic factors. The P glycoprotein might play and important role in the ...
Source: The Veterinary Journal - September 21, 2019 Category: Veterinary Research Source Type: research
Placebo-controlled pilot study of the effects of an eggshell membrane-based supplement on mobility and serum biomarkers in dogs with osteoarthritis
Publication date: Available online 13 September 2019Source: The Veterinary JournalAuthor(s): C. Muller, M. Enomoto, A. Buono, J.M. Steiner, B.D.X. LascellesAbstractOsteoarthritis (OA) is a debilitating disease in dogs. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat OA; however, many dogs do not obtain adequate pain relief with an NSAID alone. This pilot study evaluated the systemic anti-inflammatory and mobility enhancing effects of an eggshell membrane-based nutritional supplement in dogs with OA-associated pain and mobility impairment. Twenty-seven dogs with OA-associated pain were enrolled int...
Source: The Veterinary Journal - September 15, 2019 Category: Veterinary Research Source Type: research
Retrospective evaluation of prazosin and diazepam after thoracolumbar hemilaminectomy in dogs
Publication date: Available online 13 September 2019Source: The Veterinary JournalAuthor(s): K.H. Barnes, K.S. Aulakh, C. LiuAbstractManagement of urinary retention after spinal cord injury in dogs is often needed and can include use of medications to relax the urethral sphincter. This was a retrospective study evaluating two such medications, prazosin and diazepam, and whether dogs treated with these medications had different lengths of hospitalization, urinary continence levels, or development of bacteriuria compared to dogs not receiving these medications after thoracolumbar hemilaminectomy for intervertebral disc herni...
Source: The Veterinary Journal - September 15, 2019 Category: Veterinary Research Source Type: research
ABCB1 c.-6-180 T > G polymorphism and clinical risk factors in a multi-breed cohort of dogs with refractory idiopathic epilepsy
Publication date: Available online 12 September 2019Source: The Veterinary JournalAuthor(s): T. Gagliardo, G. Gandini, A. Gallucci, M. Menchetti, E. Bianchi, M.E. Turba, A. Cauduro, D.S. Corlazzoli, S. Gianni, M. Baroni, M. Bernardini, F. GentiliniAbstractEpilepsy is the most common chronic neurological disorder in dogs. Approximately 20-30% of dogs do not achieve satisfactory seizure control with two or more anti-epileptic drugs at appropriate dosages. This condition, defined as refractory epilepsy, is a multifactorial condition involving both acquired and genetic factors. The P glycoprotein might play and important role ...
Source: The Veterinary Journal - September 13, 2019 Category: Veterinary Research Source Type: research
Diffusion of fluoroquinolones into equine fetal fluids did not induce fetal lesions after enrofloxacin treatment in early gestation
Publication date: Available online 7 September 2019Source: The Veterinary JournalAuthor(s): R.E. Ellerbrock, I.F. Canisso, G. Podico, P.J. Roady, E. Uhl, F.S. Lima, Z. LiAbstractWhile recent work has suggested enrofloxacin and ciprofloxacin reach the fetoplacental unit without causing obvious lesions in the 9-month-old equine fetus or resulting foal, many practitioners still hesitate to prescribe a fluoroquinolone during pregnancy. Since early gestation is a critical time for fetal skeletal development, if fluoroquinolones are chondrotoxic to the fetus at any point during gestation, this period would be important. The aim ...
Source: The Veterinary Journal - September 8, 2019 Category: Veterinary Research Source Type: research
Interobserver agreement of an electronic von Frey device for measuring mechanical sensory thresholds in normal dogs
Publication date: Available online 4 September 2019Source: The Veterinary JournalAuthor(s): A.T. Kerns, L.B. Cook, N. Kieves, S.A. MooreAbstractElectronic von Frey aesthesiometry (VFA) has been previously reported as a useful method of mechanical quantitative sensory testing (QST) for evaluating neuropathic pain in dogs. Intraobserver agreement has been shown to be good to excellent; however, interobserver agreement has not been evaluated and is vital to the use of this technique in multicenter veterinary clinical trials in neuropathic pain. The goal of this study was to evaluate the interobserver agreement of sensory thre...
Source: The Veterinary Journal - September 5, 2019 Category: Veterinary Research Source Type: research
Editorial Board
Publication date: September 2019Source: The Veterinary Journal, Volume 251Author(s): (Source: The Veterinary Journal)
Source: The Veterinary Journal - September 4, 2019 Category: Veterinary Research Source Type: research
Publisher's Note
Publication date: September 2019Source: The Veterinary Journal, Volume 251Author(s): (Source: The Veterinary Journal)
Source: The Veterinary Journal - September 4, 2019 Category: Veterinary Research Source Type: research
A randomised controlled comparison of aspiration and non-aspiration fine-needle techniques for obtaining ultrasound-guided cytological samples from canine livers
In this study, fine-needle non-aspiration was superior to an aspiration technique for sampling canine liver, as it resulted in higher rates of diagnostic cytology samples, with greater cellularity, less haemodilution and better cytological preservation. (Source: The Veterinary Journal)
Source: The Veterinary Journal - September 1, 2019 Category: Veterinary Research Source Type: research
Measurement of chronic pain in companion animals: Priorities for future research and development based on discussions from the Pain in Animals Workshop (PAW) 2017
Publication date: Available online 28 August 2019Source: The Veterinary JournalAuthor(s): B.D.X. Lascelles, D.C. Brown, M. Conzemius, M. Gill, M.L. Oshinsky, M. SharkeyAbstractThe estimation of long-standing pain in companion animals through the measurement of different dimensions impacted by pain is a fundamental requirement if pain management, and pain therapeutic development, are to advance. Although pain management in veterinary medicine has advanced considerably in the last 20 years, there is much critical work to do in the area of measurement of chronic pain. To date, most work has centered on musculoskeletal pain, a...
Source: The Veterinary Journal - August 29, 2019 Category: Veterinary Research Source Type: research
Red light at night permits the nocturnal rise of melatonin production in horses
Publication date: Available online 22 August 2019Source: The Veterinary JournalAuthor(s): B.A. Murphy, C. O’Brien, J.A. ElliottAbstractExposure to white light at night suppresses melatonin production, impacts circadian rhythms and contributes to ill-health in humans. Human interaction with horses frequently occurs at night. We tested the hypothesis that dim red light would not suppress the nightly rise in serum melatonin levels in horses. In a crossover design, six horses were maintained for consecutive 48 h periods under a Light:Red (LR) and a Light:Dark (LD) photo-schedule. Transitions from light (>200 lux, polychr...
Source: The Veterinary Journal - August 24, 2019 Category: Veterinary Research Source Type: research
Serum concentration of homocysteine in spontaneous feline chronic kidney disease
Publication date: Available online 22 August 2019Source: The Veterinary JournalAuthor(s): M. Giraldi, S. Paltrinieri, C. Curcio, P. ScarpaAbstractSerum homocysteine (Hcy) increases in people and dogs with chronic kidney disease (CKD). Hyperhomocysteinemia (HHcy) has also been associated with CKD-related hypertension and proteinuria. The aims of this study were to: (1) validate an enzymatic method for quantification of Hcy in feline serum; (2) evaluate whether HHcy was associated with the presence and severity of CKD, proteinuria or hypertension; and (3) determine whether HHcy could predict disease progression.The intra- an...
Source: The Veterinary Journal - August 24, 2019 Category: Veterinary Research Source Type: research
Precision and accuracy of a point-of-care glucometer in horses and the effects of sample type
The objectives of this study were to determine the accuracy of glucometry in adult horses and the precision of duplicate measurements. Blood samples were collected from 62 horses into one plain syringe, one EDTA tube and three fluoride oxalate (FO) tubes. Immediately after collection, glucose concentrations in whole blood were determined, in duplicate, by glucometry from the syringe (plain whole blood [WB] group), EDTA tube (EDTA group) and one FO tube (FO group). One FO sample was used to measure plasma glucose concentration by a laboratory chemistry analyser (LAB group) ≤1 h after collection. The third FO tube was us...
Source: The Veterinary Journal - August 24, 2019 Category: Veterinary Research Source Type: research
Hair or salivary cortisol analysis to identify chronic stress in piglets?
Publication date: Available online 17 August 2019Source: The Veterinary JournalAuthor(s): S. Prims, C. Van den Hole, S. Van Cruchten, C. Van Ginneken, X. Van Ostade, C. CasteleynAbstractHair cortisol might better represent chronic stress than salivary cortisol in piglets. To test this hypothesis, 24 female, 7-day old piglets were allocated to two groups and artificially reared. The piglets in the stressed group were exposed to overcrowding (0.10 m2/piglet) and frequent mixing with unfamiliar piglets until the age of 28 days. The control group remained in an unchanging group at a density of 0.29 m2/piglet. After 3 weeks...
Source: The Veterinary Journal - August 19, 2019 Category: Veterinary Research Source Type: research
