Diagnosis of spontaneous hyperadrenocorticism in dogs. Part 1: Pathophysiology, aetiology, clinical and clinicopathological features
Publication date: Available online 23 July 2019Source: The Veterinary JournalAuthor(s): Michael Bennaim, Robert E. Shiel, Carmel T. MooneyAbstractHyperadrenocorticism is a relatively common endocrine disorder in dogs. It occurs as a result of a functional pituitary or adrenal tumour, although other causes have been rarely reported. Canine hyperadrenocorticism has been extensively described but diagnosing this disease remains challenging. Few studies have investigated the clinical and clinicopathological features helpful in differentiating dogs with hyperadrenocorticism from dogs in which the disease is suspected but eventu...
Source: The Veterinary Journal - July 25, 2019 Category: Veterinary Research Source Type: research
A short-term evaluation of a thermoplastic polyurethane implant for osteochondral defect repair in an equine model
Publication date: Available online 20 July 2019Source: The Veterinary JournalAuthor(s): N.M. Korthagen, H. Brommer, G. Hermsen, S.G.M. Plomp, G. Melsom, K. Coeleveld, S.C. Mastbergen, H. Weinans, W. van Buul, P.R. van WeerenAbstractCartilage repair remains a major challenge and treatment of (osteo)chondral defects generally results in poor quality fibrous repair tissue. Our approach aims to address some of the major biomechanical issues encountered in scaffold-based cartilage repair, such as insufficient stiffness of the scaffolds, step formation at the interface with the native tissue and inadequate integration with the o...
Source: The Veterinary Journal - July 21, 2019 Category: Veterinary Research Source Type: research
A high protein meal affects plasma insulin concentrations and amino acid metabolism in horses with equine metabolic syndrome
The objective was therefore to assess insulin and amino acid responses following intake of a high protein meal in healthy horses and those with EMS. Six mature horses diagnosed with EMS and six age-matched control horses without EMS were used. Horses were fed 2 g/kg body mass (BM) of a high protein pellet (31% crude protein) at time 0 and 30 min, for a total of 4 g/kg BM, following an overnight fast. Blood samples collected during a 4 h period were analysed for plasma glucose, insulin, amino acids and urea concentrations.Glucose concentrations were not different between groups (P = 0.2). Horses with EMS had a 9...
Source: The Veterinary Journal - July 21, 2019 Category: Veterinary Research Source Type: research
Comparison of vertical force redistribution in the pads of dogs with elbow osteoarthritis and healthy dogs
Publication date: Available online 8 July 2019Source: The Veterinary JournalAuthor(s): L. Braun, A. Tichy, C. Peham, B. BockstahlerAbstractKinetic analyses are becoming increasingly important for biomechanical research in veterinary medicine and as a diagnostic tool for orthopaedic examinations in dogs. Such analysis enables accurate evaluation of the vertical force distribution (VFD) in canine paw pads. The aim of this study was to assess peak vertical force (PFz) as a percent of total force (%TF), vertical impulse (IFz, %TF) and time of occurrence of PFz (TPFz) as a percent of the stance phase (%SP) in the pads of all fo...
Source: The Veterinary Journal - July 9, 2019 Category: Veterinary Research Source Type: research
Pregabalin for the treatment of syringomyelia-associated neuropathic pain in dogs: A randomised, placebo-controlled, double-masked clinical trial
This study demonstrates the efficacy of pregabalin for the treatment of NeP due to CM/SM on daily pain scores recorded by dog owners. Pregabalin significantly reduced mechanical hyperalgesia, cold hyperalgesia (0 °C) and allodynia (15 °C) compared to placebo. Pregabalin was non-cumulative and well tolerated with occasional mild sedation. (Source: The Veterinary Journal)
Source: The Veterinary Journal - July 6, 2019 Category: Veterinary Research Source Type: research
The influence of trimming of the hoof wall on the damage of laminar tissue after loading: An in vitro study
Publication date: Available online 4 July 2019Source: The Veterinary JournalAuthor(s): S. Moeller, B. Patan-Zugaj, T. Daeullary, A. Tichy, T.F. LickaAbstractLaminitis is associated with failure of the suspensory apparatus of the distal phalanx (SADP) connecting the distal phalanx to the hoof wall. The specific aim of this study was to examine in vitro whether thinning of the hoof wall leading to increased deformability influences the damage of the laminar tissue created by loading of the hoof. Paired cadaver forelimbs from twelve horses were used. For each pair, the hoof wall from one hoof was thinned by 25%; this was asce...
Source: The Veterinary Journal - July 6, 2019 Category: Veterinary Research Source Type: research
Measurement of chronic pain in companion animals: Discussions from the Pain in Animals Workshop (PAW) 2017
Publication date: Available online 3 July 2019Source: The Veterinary JournalAuthor(s): B.D.X. Lascelles, D.C. Brown, M.G. Conzemius, M. Gill, M.L. Oshinsky, M. SharkeyAbstractIn the face of increasing recognition and interest in treating chronic pain in companion animals, we struggle with a lack of therapeutic options. A significant barrier to the development of new therapeutics, or the critical evaluation of current therapies, is our inability to accurately measure chronic pain and its impact on companion animals. Over the last 20 years, much progress has been made in developing methods to measure chronic pain via subject...
Source: The Veterinary Journal - July 4, 2019 Category: Veterinary Research Source Type: research
Bacterial osteomyelitis in veterinary orthopaedics: Pathophysiology, clinical presentation and advances in treatment across multiple species
Publication date: Available online 25 June 2019Source: The Veterinary JournalAuthor(s): Fabian Gieling, Sarah Peters, Christoph Erichsen, R. Geoff Richards, Stephan Zeiter, T. Fintan MoriartyAbstractBacterial osteomyelitis in veterinary patients can be challenging to diagnose and treat, given limited therapeutic options and reported success rates. Osteomyelitis is frequently associated with surgical implant devices, including those required to optimise stability and healing of fractures. However, management of osteomyelitis sometimes necessitates the removal of these surgical implant devices in order to eradicate infection...
Source: The Veterinary Journal - June 27, 2019 Category: Veterinary Research Source Type: research
Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease
Publication date: Available online 26 June 2019Source: The Veterinary JournalAuthor(s): L.B. Christiansen, S.E. Cremer, A. Helander, Tine Madsen, M.J. Reimann, J.E. Møller, K. Höglund, I. Ljungvall, J. Häggström, L. Høier OlsenAbstractHigher concentrations of circulating serotonin have been reported in Cavalier King Charles spaniels (CKCS) compared to other dog breeds. The CKCS is also a breed highly predisposed to myxomatous mitral valve disease (MMVD). The aim of this study was to determine urine concentrations of 5-hydroxyindoleacetic acid (5-HIAA), the major metabolite and excretion product of serotonin, in a popu...
Source: The Veterinary Journal - June 27, 2019 Category: Veterinary Research Source Type: research
Editorial Board
Publication date: July 2019Source: The Veterinary Journal, Volume 249Author(s): (Source: The Veterinary Journal)
Source: The Veterinary Journal - June 24, 2019 Category: Veterinary Research Source Type: research
Footbathing, formalin and foot trimming: The 3Fs associated with granulomas and shelly hoof in sheep
Publication date: Available online 21 June 2019Source: The Veterinary JournalAuthor(s): M.C. Reeves, N.S. Prosser, E.M. Monaghan, L.E. GreenAbstractGranulomas and shelly hoof (SH), are lesions of sheep feet. Our objective was to use data from four questionnaires on lameness sent to English sheep farmers in 2004, 2013, 2014 and 2015 to further understanding of the risks and aetiologies of both lesions.Granulomas were more likely in flocks where routine foot trimming (odds ratio [OR] = 3.17; 95% confidence intervals [CI] 1.11–11.47) and routine footbathing (OR = 2.38; 95% CI 1.19–4.83) were practised than where t...
Source: The Veterinary Journal - June 22, 2019 Category: Veterinary Research Source Type: research
Erratum to: “Clinical presentation, diagnostic findings, and outcome of adult horses with equine coronavirus infection at a veterinary teaching hospital: 33 cases (2012–2018)” [Vet. J. 248 (2019) 95–100]
Publication date: August 2019Source: The Veterinary Journal, Volume 250Author(s): E.H. Berryhill, K.G. Magdesian, M. Aleman, N. Pusterla (Source: The Veterinary Journal)
Source: The Veterinary Journal - June 13, 2019 Category: Veterinary Research Source Type: research
Risk factors associated with excessive negative energy balance in commercial United Kingdom dairy herds
This study assessed risk factors associated with excessive negative energy balance (eNEB) in UK dairy cows between April 2006 and March 2015. Blood samples were analysed for β-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA) and glucose. Following removal of all potential duplicate cows, a final dataset of 69,161 unique individual cows was obtained including biochemical results, individual cow and feed data.Generalised linear mixed-effect models and multivariable classification tree-based models showed that individual cow risk factors for eNEB included: (1) days relative to predicted calving date (dry cows); (2) d...
Source: The Veterinary Journal - June 12, 2019 Category: Veterinary Research Source Type: research
Race-day performance of horses with epiglottic entrapment, and following surgical correction using intra-oral curved bistoury hook in anaesthetised horses
This study may assist veterinarians advising clients in the decision-making process when epiglottic entrapment is diagnosed in a racehorse. (Source: The Veterinary Journal)
Source: The Veterinary Journal - June 8, 2019 Category: Veterinary Research Source Type: research
Canine papillomavirus types 1 and 2 in classical papillomas: High abundance, different morphological associations and frequent co-infections
Publication date: Available online 4 June 2019Source: The Veterinary JournalAuthor(s): C.E. Lange, S.H. Jennings, A. Diallo, J. LyonsAbstractCanine papillomatosis is mainly attributed to papillomavirus infection. Papillomavirus DNA is also frequently identified in healthy skin, and evidence of high papillomavirus diversity complicates this simplistic view of causality. The aim of this study was to determine how frequently canine papillomas contain papillomavirus DNA and express viral protein, and how these factors correlate to the histology and anatomic location. Fifty-three archived, formalin-fixed samples of canine papil...
Source: The Veterinary Journal - June 5, 2019 Category: Veterinary Research Source Type: research
