Sleep disturbances and sexual function among men aged 45–75 years in an urban area of Iran
Conclusion According to the high prevalence of sleep disorders in men as well as its association with sexual dysfunction, adopting health measures in this regard is necessary. (Source: Sleep Science)
Source: Sleep Science - January 20, 2016 Category: Sleep Medicine Source Type: research

Extreme late chronotypes and social jetlag challenged by Antarctic conditions in a population of university students from Uruguay
Publication date: Available online 15 January 2016 Source:Sleep Science Author(s): Bettina Tassino, Stefany Horta, Noelia Santana, Rosa Levandovski, Ana Silva In humans, a person’s chronotype depends on environmental cues and on individual characteristics, with late chronotypes prevailing in youth. Social jetlag (SJL), the misalignment between an individual׳s biological clock and social time, is higher in late chronotypes. Strong SJL is expected in Uruguayan university students with morning class schedules and very late entertainment activities. Sleep disorders have been reported in Antarctic inhabitants, ...
Source: Sleep Science - January 16, 2016 Category: Sleep Medicine Source Type: research

Caffeine intake has no effect on sleep quality in community dwellers living in a rural Ecuadorian village (The Atahualpa Project)
Publication date: Available online 4 January 2016 Source:Sleep Science Author(s): Oscar H. Del Brutto, Robertino M. Mera, Mauricio Zambrano, Pablo R. Castillo More information is needed to better understand the effect of caffeine on sleep quality at the community level. In a population-based, cross-sectional study design, we aimed to assess the effect of caffeine intake on sleep quality by the use of a multivariate exposure-effect model, adjusted for relevant confounders. All Atahualpa residents aged ≥40 years were identified during a door-to-door survey and interviewed with the Pittsburgh Sleep Quality Index...
Source: Sleep Science - January 11, 2016 Category: Sleep Medicine Source Type: research

Immunomodulation by classical conditioning in NZB/W (F1) mice: Lifespan and diurnal variation
Publication date: Available online 4 January 2016 Source:Sleep Science Author(s): Mario André Leocadiô Miguel, Luiz Menna-Barreto Systemic Lupus Eritematosus (SLE) is a systemic inflammatory disease often treated with the agent cyclophosphamide (CY), known by provoking important adverse reactions to the organism. Ader and Cohen have demonstrated an alternative way of administrating this agent based on pavlovian conditioning, in order to reduce the aggression caused by CY. Considering the influence of the temporal organization on learning and memory processes, the purpose of this study was to understand the tempor...
Source: Sleep Science - January 11, 2016 Category: Sleep Medicine Source Type: research

REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects
Publication date: Available online 10 November 2015 Source:Sleep Science Author(s): Ana Carolina D. Noseda, Adriano D.S. Targa, Lais S. Rodrigues, Mariana F. Aurich, Marcelo M.S. Lima The aim of this study was to investigate the possible anxiolytic-like effects of striatal MT2 activation, and its counteraction induced by the selective blockade of this receptor. Furthermore, we analyzed this condition under the paradigm of rapid eye movement (REM) sleep deprivation (REMSD) and the animal model of Parkinson’s disease (PD) induced by rotenone. Male Wistar rats were infused with intranigral rotenone (12μg/μL)...
Source: Sleep Science - November 11, 2015 Category: Sleep Medicine Source Type: research

Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study
This study builds on recent evidence that sleep may be influenced by gut microbiota, by assessing whether changes to microbiota in a clinical population known to have both poor sleep and high rates of colonization with gram-positive faecal Streptococcus, can improve sleep. Twenty-one CFS participants completed a 22-day open label trial. Faecal microbiota analysis was performed at baseline and at the end of the trial. Participants were administered erythromycin 400mg b.d. for 6 days. Actigraphy and questionnaires were used to monitor sleep, symptoms and mood. Changes in patients who showed a clinically significant change in...
Source: Sleep Science - October 25, 2015 Category: Sleep Medicine Source Type: research

The family role in children׳s sleep disturbances: Results from a cross-sectional study in a Portuguese Urban pediatric population
Conclusion Family structure plays a non-negligible role in children’s sleep habits. Daily performance of children with SDB may become compromised. (Source: Sleep Science)
Source: Sleep Science - October 11, 2015 Category: Sleep Medicine Source Type: research

Pedunculopontine arousal system physiology—Effects of psychostimulant abuse
Publication date: Available online 10 October 2015 Source:Sleep Science Author(s): Francisco J. Urbano, Verónica Bisagno, Betina González, María Celeste Rivero-Echeto, Javier A. Muñiz, Brennon Luster, Stasia D’Onofrio, Susan Mahaffey, Edgar Garcia-Rill This review describes the interactions between the pedunculopontine nucleus (PPN), the ventral tegmental area (VTA), and the thalamocortical system. Experiments using modulators of cholinergic receptors in the PPN clarified its role on psychostimulant-induced locomotion. PPN activation was found to be involved in the animal’s voluntary search fo...
Source: Sleep Science - October 11, 2015 Category: Sleep Medicine Source Type: research

Interactions between sleep, stress, and metabolism: From physiological to pathological conditions
Publication date: Available online 28 September 2015 Source:Sleep Science Author(s): Camila Hirotsu, Sergio Tufik, Monica Levy Andersen Poor sleep quality due to sleep disorders and sleep loss is highly prevalent in the modern society. Underlying mechanisms show that stress is involved in the relationship between sleep and metabolism through hypothalamic–pituitary–adrenal (HPA) axis activation. Sleep deprivation and sleep disorders are associated with maladaptive changes in the HPA axis, leading to neuroendocrine dysregulation. Excess of glucocorticoids increase glucose and insulin and decrease adiponectin le...
Source: Sleep Science - September 29, 2015 Category: Sleep Medicine Source Type: research

Pedunculopontine arousal system physiology – Deep brain stimulation (DBS)
Publication date: Available online 25 September 2015 Source:Sleep Science Author(s): Edgar Garcia-Rill, Brennon Luster, Stasia D’Onofrio, Susan Mahaffey, Veronica Bisagno, Francisco J. Urbano This review describes the wake/sleep symptoms present in Parkinson׳s disease, and the role of the pedunculopontine nucleus in these symptoms. The physiology of PPN cells is important not only because it is a major element of the reticular activating system, but also because it is a novel target for deep brain stimulation in the treatment of gait and postural deficits in Parkinson׳s disease. A greater understanding ...
Source: Sleep Science - September 26, 2015 Category: Sleep Medicine Source Type: research

Effects of an adapted mattress in musculoskeletal pain and sleep quality in institutionalized elders
Publication date: Available online 25 September 2015 Source:Sleep Science Author(s): Anculle Arauco Victor, Zamudio Herrera Rodrigo, Mendiola Yamasato Andrea, Guillen Mendoza Daniel, Pedro José Ortiz Saavedra, Tania Tello Rodríguez, Darwin Vizcarra-Escobar We aimed to evaluate the impact in sleep quality and musculoskeletal pain of a Medium-Firm Mattress (MFM), and their relationship with objective sleep parameters in a group of institutionalized elders. The sample size included forty older adults with musculoskeletal pain. We did a clinical assessment at baseline and weekly trough the study period of f...
Source: Sleep Science - September 26, 2015 Category: Sleep Medicine Source Type: research

The role of flow limitation as an important diagnostic tool and clinical finding in mild sleep-disordered breathing
Publication date: Available online 3 September 2015 Source:Sleep Science Author(s): Nevin Arora, Gerard Meskill, Christian Guilleminault Obstructive sleep apnea (OSA) is defined by quantifying apneas and hypopneas along with symptoms suggesting sleep disruption. Subtler forms of sleep-disordered breathing can be missed when this criteria is used. Newer technologies allow for non-invasive detection of flow limitation, however consensus classification is needed. Subjects with flow limitation demonstrate electroencephalogram changes and clinical symptoms indicating sleep fragmentation. Flow limitation may be increas...
Source: Sleep Science - September 5, 2015 Category: Sleep Medicine Source Type: research

Mysteries of pedunculopontine nucleus physiology: Towards a deeper understanding of arousal and neuropsychiatric disorders
Publication date: April–June 2015 Source:Sleep Science, Volume 8, Issue 2 Author(s): Subimal Datta (Source: Sleep Science)
Source: Sleep Science - August 29, 2015 Category: Sleep Medicine Source Type: research

Assessment of interobserver concordance in polysomnography scoring of sleep bruxism
Conclusion It was found a good inter-examiner concordance rate in SB scoring in absence of audio video monitoring. (Source: Sleep Science)
Source: Sleep Science - August 25, 2015 Category: Sleep Medicine Source Type: research

Urinary proteomic profiling in severe obesity and obstructive sleep apnoea with CPAP treatment
Conclusions The urinary proteome is compared in OSA with CPAP and without OSA in severe obesity. The effects of CPAP on OSA may lead to changes in the urinary peptides but further research work is needed to investigate the potential role for urinary proteomics in characterising urinary peptide profiles in OSA. (Source: Sleep Science)
Source: Sleep Science - July 18, 2015 Category: Sleep Medicine Source Type: research