Cataplexy as a side effect of modafinil in a patient without narcolepsy
The objective of this article is to describe an unexpected side effect of the use of modafinil in a patient with incorrect diagnosis of narcolepsy. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Moebius syndrome and narcolepsy: A case dissertation
The objective of this dissertation is to describe and discuss a case of Moebius syndrome with diurnal excessive sleepiness as a differential diagnosis for narcolepsy. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Cognitive behavioral treatment for narcolepsy: can it complement pharmacotherapy?
Publication date: March 2014 Source:Sleep Science, Volume 7, Issue 1 Author(s): Hernán Andrés Marín Agudelo , Ulises Jiménez Correa , Juan Carlos Sierra , Seithikurippu R. Pandi-Perumal , Carlos H. Schenck Sleep medicine in general and psychology in particular have recently developed cognitive behavioral treatment for narcolepsy (CBT-N). Despite a growing interest in this topic, most studies since 2007 have reviewed CBT applications for other sleep disorders. Currently, 6 reviews have been published on narcolepsy, with an expert consensus being reached that CBT represented an important adjunctive treatment for...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

The hypocretins (orexins) mediate the “phasic” components of REM sleep: A new hypothesis
Publication date: March 2014 Source:Sleep Science, Volume 7, Issue 1 Author(s): Pablo Torterolo , Michael H. Chase In 1998, a group of phenotypically distinct neurons were discovered in the postero-lateral hypothalamus which contained the neuropeptides hypocretin 1 and hypocretin 2 (also called orexin A and orexin B), which are excitatory neuromodulators. Hypocretinergic neurons project throughout the central nervous system and have been involved in the generation and maintenance of wakefulness. The sleep disorder narcolepsy, characterized by hypersomnia and cataplexy, is produced by degeneration of these neurons. Th...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

The nature of excessive sleepiness and sudden sleep onset in Parkinson׳s disease
The objectives are to identify clinical characteristics and factors associated with EDS and SOS episodes. Methods Clinical demographic data were recorded (N=100, mean age=65.0±10.4). EDS was identified by the Epworth Sleepiness Scale (ESS>10) and SOS episodes were registered. Disease severity was evaluated by the Unified Parkinson׳s Disease Rating Scale (UPDRS, I, II, and III), sleep disturbances by the Parkinson׳s Disease Sleep Scale (PDSS<100), depressive symptoms by the Beck Depression Inventory (BDI>10) and rapid eye movement (REM) sleep behavior disorder (RBD) by the REM sleep behavior scale....
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Narcolepsy and the Sickness Impact Profile: A general health status measure
Discussion The SIP correlated with ESS and UNS, and captured unique aspects of the impact of narcolepsy on patients. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

A journey through narcolepsy diagnosis: From ICSD 1 to ICSD 3
Publication date: March 2014 Source:Sleep Science, Volume 7, Issue 1 Author(s): Laís F. Berro , Sergio B. Tufik , Sergio Tufik (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Narcolepsy – Between the dream and reality
Publication date: March 2014 Source:Sleep Science, Volume 7, Issue 1 Author(s): Fernando Morgadinho Santos Coelho (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Kleine–Levin Syndrome: A case report
Publication date: Available online 9 September 2014 Source:Sleep Science Author(s): Taís Figueiredo de Araújo Lima , Nilce Sanny Costa da Silva Behrens , Eduardo Lopes , Danielle Pereira , Hassana de Almeida Fonseca , Paola Oliveira Cavalcanti , Marcia Pradella-Hallinan , Juliana Castro , Sergio Tufik , Fernando Morgadinho Santos Coelho The Kleine–Levin Syndrome is a differential diagnosis for patients with diurnal excessive sleepiness and a suspicion of narcolepsy. It is characterized by paroxysmal attacks of diurnal excessive sleepiness, associated with one or more symptoms of hyperphagia, hypersexualit...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Examination of wrist and hip actigraphy using a novel sleep estimation procedure
Discussion The results indicate that with some refinement, the spline regression method has the potential to improve sleep estimates obtained using wrist actigraphy. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

The impact of sleep duration on self-rated health
Conclusion The sleep duration issue should be considered when inquiring about health conditions, as this factor can lead to adverse results in global health status. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Relationship between chronotype and quality of sleep in medical students at the Federal University of Paraiba, Brazil
Conclusion These findings demonstrate that the evening chronotype was associated with poor quality of sleep in medical students, but not with increased daytime sleepiness, with potential impairment to their academic performance and quality of life. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Sedentary behavior and sleep efficiency in active community-dwelling older adults
Conclusions This study found a small significant association between the time spent sedentary and sleep efficiency, despite high levels of activity in this older adult group. (Source: Sleep Science)
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

Treatment of sleep central apnea with non-invasive mechanical ventilation with 2 levels of positive pressure (bilevel) in a patient with myotonic dystrophy type 1
Publication date: Available online 16 September 2014 Source:Sleep Science Author(s): Ricardo Tera Akamine , Luís Fernando Grossklauss , Gustavo Antonio Moreira , Marcia Pradella-Hallinan , Marco Antônio Chiéia , Denis Mesquita , Acary Souza Bulle Oliveira , Sergio Tufik We are reporting a case of a 29 year-old female with diagnosis of myotonic dystrophy type 1 (Steinert’s disease) with excessive daytime sleepiness, muscle fatigue, snoring, frequent arousals, non-restorative sleep, and witnessed apneas. Pulmonary function tests revealed a mild decrease of forced vital capacity. Nocturnal polysomnography sho...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research

The beneficial effects of massage therapy for insomnia in postmenopausal women
Publication date: Available online 16 September 2014 Source:Sleep Science Author(s): H. Hachul , D.S. Oliveira , L.R.A. Bittencourt , M.L. Andersen , S. Tufik With increases life expectancy, the incidence of undesirable manifestations of menopause has increased as well. The effects of lost ovarian function include progressive decrease in estradiol secretion, trophic changes in the breast, vasomotor symptoms, anxiety, depression, and sleep disorders. Insomnia, which has physiological consequences and can result in a loss of quality of life, is prevalent in women after menopause. Hormone therapy has been widely used...
Source: Sleep Science - November 6, 2014 Category: Sleep Medicine Source Type: research