Brain injury during transition in the newborn with CHD: Hazards of the preoperative period
Congenital heart defects (CHD) are the most common birth defect, affecting approximately 30,000 newborns each year. Nearly one third of these children require cardiac surgery during the neonatal period.1 While surgical advancements over the last several decades have improved survival, neurodevelopmental disabilities remain a significant morbidity among survivors. As a result, clinical and investigative focus has shifted from survival beyond the neonatal period toward neurologic sequelae. Magnetic resonance imaging (MRI) studies during the neonatal period in this population reveal abnormal development including microcephaly...
Source: Seminars in Pediatric Neurology - May 11, 2018 Category: Neurology Authors: Jennifer M. Lynch, J. William Gaynor, Daniel J. Licht Tags: 4th issue-Fetal Neurology issue Source Type: research
Socioeconomic Status and Pediatric Neurologic Disorders: Current Evidence
This article focuses on the relationship between SES and pediatric epilepsy, cerebral palsy, autism spectrum disorder, and intellectual disability. Disparities in the prevalence and long-term impact of SES on functioning in persons with disabilities are observed worldwide. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Maureen S. Durkin, Marshalyn Yeargin-Allsopp Source Type: research
Socioeconomic Status and Pediatric Neurologic Disorders: Current Evidence ☆☆
This article focuses on the relationship between SES and pediatric epilepsy, cerebral palsy, au tism spectrum disorder, and intellectual disability. Disparities in the prevalence and long-term impact of SES on functioning in persons with disabilities are observed worldwide. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Maureen S. Durkin, Marshalyn Yeargin-Allsopp Source Type: research
Justice and Neurodevelopmental Disability: Moral-Political Philosophies, Policies, and Their Outcomes
Neurodevelopmental disabilities such as cerebral palsy and autism touch a population which has been dubbed to be “doubly vulnerable”. Individuals with neurodevelopmental disability have conditions that impair their cognition, communication, mobility or social interactions and they also rely on others to make decisions on their behalf. Accordingly, these children – as described in other contributions of t his special issue – are particularly prone to suffer from systemic (i.e., social, economic, and political) conditions that give or prevent access to quality and timely healthcare and social services as well as econ...
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Eric Racine, Roxanne Caron, Mich èle Stanton-Jean Source Type: research
Promoting the human rights of children with neurologic conditions
Children with neurologic conditions are children first, and as such they benefit from international conventions, and national treaties, policies and regulations that have been developed to support their optimal development and ultimately safeguard their human rights. These regulations also exist to serve as guidance in the creation of comprehensive systems of care, inclusive environments, accessible societies and communities that allow these children to thrive and to achieve the best of their intrinsic capacities. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Keiko Shikako-Thomas, Meaghan Shevell Source Type: research
Socioeconomic Status and Pediatric Neurologic Disorders: Current Evidence ☆☆
This article focuses on the relationship between SES and pediatric epilepsy, cerebral palsy, au tism spectrum disorder, and intellectual disability. Disparities in the prevalence and long-term impact of SES on functioning in persons with disabilities are observed worldwide. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Maureen S. Durkin, Marshalyn Yeargin-Allsopp Source Type: research
Justice and Neurodevelopmental Disability: Moral-Political Philosophies, Policies, and Their Outcomes
Neurodevelopmental disabilities such as cerebral palsy and autism touch a population which has been dubbed to be “doubly vulnerable”. Individuals with neurodevelopmental disability have conditions that impair their cognition, communication, mobility or social interactions and they also rely on others to make decisions on their behalf. Accordingly, these children – as described in other contributions of t his special issue – are particularly prone to suffer from systemic (i.e., social, economic, and political) conditions that give or prevent access to quality and timely healthcare and social services as well as econ...
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Eric Racine, Roxanne Caron, Mich èle Stanton-Jean Source Type: research
Promoting the human rights of children with neurologic conditions
Children with neurologic conditions are children first, and as such they benefit from international conventions, and national treaties, policies and regulations that have been developed to support their optimal development and ultimately safeguard their human rights. These regulations also exist to serve as guidance in the creation of comprehensive systems of care, inclusive environments, accessible societies and communities that allow these children to thrive and to achieve the best of their intrinsic capacities. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - March 26, 2018 Category: Neurology Authors: Keiko Shikako-Thomas, Meaghan Shevell Source Type: research
Movement Disorders and Neurometabolic Diseases
Many inherited metabolic diseases or inborn errors of metabolism (IEM) cause movement disorders in children. This review focuses on chorea, dystonia, myoclonus, tremor, and parkinsonism. Broad neurometabolic categories commonly responsible for pediatric movement disorders include mitochondrial cytopathies, organic acidemias, mineral metabolism and transport disorders, neurotransmitter diseases, purine metabolism abnormalities, lipid storage conditions, and creatine metabolism dysfunction. Each movement disorder can be caused by many IEM and several of them can cause multiple movement abnormalities. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - February 15, 2018 Category: Neurology Authors: Celanie K. Christensen, Laurence Walsh Source Type: research
Movement Disorders and Neurometabolic Diseases
Many inherited metabolic disorders cause movement disorders in children. This review focuses on chorea, dystonia, myoclonus, tremor, and parkinsonism. Broad categories commonly responsible for pediatric movement disorders include mitochondrial disorders, organic acidemias, mineral metabolism and transport disorders, neurotransmitter diseases, purine metabolism disorders, lipid storage disorders, and disorders of creatine metabolism. Each movement disorder can be caused by many different inherited metabolic disorders and several of the inherited metabolic disorders can cause multiple movement abnormalities. (Source: Seminar...
Source: Seminars in Pediatric Neurology - February 15, 2018 Category: Neurology Authors: Celanie K. Christensen, Laurence Walsh Source Type: research
Introduction
Movement disorders are a heterogeneous group of conditions that affect a large percentage of the pediatric population. Some movement disorders, like stereotypies and tics, are extremely common, whereas others are vanishingly rare with only a few cases reported in the literature. Movement disorders can arise secondary to other conditions such as stroke or autoimmune diseases or be the primary presenting symptom as in the case of tic disorders; they may be acquired or genetic in origin.1,2 Pediatric movement disorders can cause significant functional and psychological impairment to both the child and caregivers. (Source: Sem...
Source: Seminars in Pediatric Neurology - February 13, 2018 Category: Neurology Authors: Karen S. Carvalho, Daphne M. Hasbani Source Type: research
Introduction
Movement disorders are a heterogeneous group of conditions that affect a large percentage of the pediatric population. Some movement disorders, like stereotypies and tics, are extremely common, while others are vanishingly rare with only a few cases reported in the literature. Movement disorders can arise secondary to other conditions such as stroke or autoimmune diseases or be the primary presenting symptom as in the case of tic disorders; they may be acquired or genetic in origin.1,2 Pediatric movement disorders can cause significant functional and psychological impairment to both the child and caregivers. (Source: Semin...
Source: Seminars in Pediatric Neurology - February 13, 2018 Category: Neurology Authors: Karen S. Carvalho, Daphne M. Hasbani Source Type: research
Pediatric Iatrogenic Movement Disorders
The acute development of a movement disorder is often a dramatic and frightening experience for patients and families, often requiring urgent or emergent evaluation by a neurologist. In the assessment of these patients, one relies on the history, physical and neurologic examination to determine the etiology of the condition. We aim to demonstrate that a thorough medication history is an incredibly critical part of this evaluation as iatrogenic movement disorders can arise from exposure not only to psychoactive medications, but from drugs prescribed for a variety of nonneurologic disorders. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - February 12, 2018 Category: Neurology Authors: Deepti Nagesh, Marcie Goeden, Keith A. Coffman Source Type: research
Pediatric Iatrogenic Movement Disorders
The acute development of a movement disorder is often a dramatic and frightening experience for patients and families, often requiring urgent or emergent evaluation by a neurologist. In the evaluation of these patients, one relies on the history, physical and neurologic examination to determine the etiology of the condition.We aim to demonstrate that a thorough medication history is an incredibly critical part of this evaluation as iatrogenic movement disorders can arise from exposure not only to psychoactive medications, but from medications prescribed for a variety of non-neurologic disorders. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - February 12, 2018 Category: Neurology Authors: Deepti Nagesh, Marcie Goeden, Keith A. Coffman Source Type: research
The Twists of Pediatric Dystonia: Phenomenology, Classification, and Genetics
This article aims to provide a practical review of pediatric dystonia from a clinician ’s perspective. The focus is on the underlying genetic causes, recent findings, and treatable conditions. Dystonia can occur in an isolated fashion or accompanied by other neurological or systemic features. The clinical presentation is often a complex overlap of neurological findings with a large differential diagnosis. We recommend an approach guided by thorough clinical evaluation, brain magnetic resonance imaging (MRI), biochemical analysis, and genetic testing to hone in on the diagnosis. (Source: Seminars in Pediatric Neurology)
Source: Seminars in Pediatric Neurology - February 8, 2018 Category: Neurology Authors: Inge A. Meijer, Toni S. Pearson Source Type: research
