Salience, central executive, and sensorimotor network functional connectivity alterations in failed back surgery syndrome
Conclusions FBSS is associated with altered patterns of functional connectivity in the SN, CEN, and SeN. Taken together with our previous work, this reveals that a chronic pain condition can have a dramatic effect on the connectivity of multiple resting state networks. Implications These data suggest that a chronic pain condition—FBSS—is associated with disruptions to networks of functional connectivity in brain areas that are involved in numerous functions, including pain processing, sensation, and movement. It is possible that the alterations in these networks may contribute to other common chronic pain comorbiditie...
Source: Scandinavian Journal of Pain - February 19, 2017 Category: Anesthesiology Source Type: research
New knowledge reduces risk of damage to spinal cord from spinal haematoma after epidural- or spinal-analgesia and from spinal cord stimulator leads
Publication date: Available online 16 February 2017 Source:Scandinavian Journal of Pain Author(s): Harald Breivik (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - February 16, 2017 Category: Anesthesiology Source Type: research
A possible biomarker of low back pain: 18F-FDeoxyGlucose uptake in PETscan and CT of the spinal cord
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Torsten Gordh (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - February 10, 2017 Category: Anesthesiology Source Type: research
How can pain management be improved in hospitalized patients?
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Lone Nikolajsen, Nina Buch (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - February 7, 2017 Category: Anesthesiology Source Type: research
Cardiovascular risk reduction as a population strategy for preventing pain?
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Pekka Mäntyselkä (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - February 7, 2017 Category: Anesthesiology Source Type: research
Effect of intrathecal glucocorticoids on the central glucocorticoid receptor in a rat nerve ligation model
Conclusions In intrathecal MPA treated rats, tGR mRNA levels decreased after SNL. However this did not result in lower tGR and pGR protein levels compared to saline controls, and did not decrease ligation-induced mechanical hypersensitivity. Implications Intrathecal MPA treatment after SNL did not result in lower tGR and pGR levels within the SDH and DRG compared to saline controls. In present study we did not differentiate between the various isoforms of the GR which might clarify this finding. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - February 2, 2017 Category: Anesthesiology Source Type: research
Patients ’ subjective acute pain rating scales (VAS, NRS) are fine; more elaborate evaluations needed for chronic pain, especially in the elderly and demented patients
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Harald Breivik (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - January 29, 2017 Category: Anesthesiology Source Type: research
How do medical students use and understand pain rating scales?
Conclusions The study requires replication, particularly for clinical experience, where we found no significant difference in estimation of another's pain over the first three years of medical students’ clinical exposure, but the comparison was underpowered. Despite no systematic individual difference in using pain ratings, there was a marked effect of rating another's worst pain higher when the rater had previously rated his/her own worst pain. This suggests anchoring estimate of another's pain in personal pain experience, and a possible way to mitigate clinicians’ underestimation of patients’ pain. Medical students...
Source: Scandinavian Journal of Pain - January 19, 2017 Category: Anesthesiology Source Type: research
Pain and major depressive disorder: Associations with cognitive impairment as measured by the THINC-integrated tool (THINC-it)
Conclusions Results indicated that pain is associated with increased self-rated and objective cognitive deficits in adults with MDD. Implications The study herein provides preliminary evidence demonstrating that adults with MDD reporting pain symptomatology and poorer subjective cognitive function is predictive of poorer objective cognitive performance. THINC-it is capable of detecting cognitive dysfunction amongst adults with MDD and pain. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - January 9, 2017 Category: Anesthesiology Source Type: research
Exercising non-painful muscles can induce hypoalgesia in individuals with chronic pain
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Henrik Bjarke Vaegter (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - January 9, 2017 Category: Anesthesiology Source Type: research
Intrathecal management of complex regional pain syndrome: A case report and literature
Conclusion The use of intrathecal medications is useful for pain control in CRPS patients. Implications We provide a framework for treatment of CRPS, which could be useful for practitioners dealing with this difficult and painful condition. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - January 6, 2017 Category: Anesthesiology Source Type: research
Invasive intervention for “intractable” Complex Regional Pain Syndromes (CRPS)?
Publication date: January 2017 Source:Scandinavian Journal of Pain, Volume 14 Author(s): Harald Breivik (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - January 6, 2017 Category: Anesthesiology Source Type: research
Is musculoskeletal pain associated with work engagement?
Publication date: April 2017 Source:Scandinavian Journal of Pain, Volume 15 Author(s): Stein Knardahl (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - December 29, 2016 Category: Anesthesiology Source Type: research
Specific symptoms and signs of unstable back segments and curative surgery?
Publication date: Available online 29 December 2016 Source:Scandinavian Journal of Pain Author(s): Jens Ivar Brox (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - December 28, 2016 Category: Anesthesiology Source Type: research
Detection of nociceptive-related metabolic activity in the spinal cord of low back pain patients using 18F-FDG PET/CT
Conclusions Patients with LBP show increased uptake of 18F-FDG in the caudal aspect of the thoracic spinal cord, compared to patients without LBP. Implications This paper demonstrates the potential of 18F-FDG PET/CT as a biomarker of increased metabolic activity in the spinal cord related to LBP. As such, it could potentially aid in the treatment of LBP by localizing physiologically active spinal cord regions and guiding minimally invasive delivery of analgesics or stimulators to relevant levels of the spinal cord. (Source: Scandinavian Journal of Pain)
Source: Scandinavian Journal of Pain - December 24, 2016 Category: Anesthesiology Source Type: research
