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Foxo3 gene expression and oxidative status in beta-thalassemia minor subjects
Conclusions: The lack of systemic oxidative imbalance demonstrated by thiobarbituric acid reactive species is correlated to the observation of normal FoxO3 gene expression in mononuclear cells of peripheral blood. However, an imbalanced antioxidant state was shown by the erythrocyte catalase activity/hemoglobin ratio in beta-thalassemia minor carriers. It would be necessary to study FoxO3 gene expression in reticulocytes to elucidate the role of FoxO3 in this pathology. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Interleukin-10 haplotypes are not associated with acute cerebral ischemia or high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia
Conclusion: Interleukin-10 haplotypes were not associated with the risk of acute cerebral ischemia or high-risk transcranial Doppler velocity in children with sickle cell anemia from the state of Minas Gerais, Brazil. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Seroprevalence, cost per donation and reduction in blood supply due to positive and indeterminate results for infectious markers in a blood bank in Lima, Peru
Conclusion: Seroprevalence was lower than the regional mean, but the prevalence of indeterminate results was elevated causing a great impact on blood supply and economic losses to this institution. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Tides within ourselves: how posture can affect blood volume, blood cells and clinical reasoning
(Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Stressed ends: telomere attrition in chronic diseases
(Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Human platelet antigens and primary immune thrombocytopenia
(Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - July 3, 2017 Category: Hematology Source Type: research

Erratum to "Diagnosis and treatment of chronic lymphocytic leukemia: Recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia" [Rev Bras Hematol Hemoter. 2016;38(4):346–357]
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Red cell autoantibody mimicking anti-C specificity: a rare manifestation
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Primary breast lymphoma: a case report
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Administration of all-trans retinoic acid through enteral tubes in acute promyelocytic leukemia: the handling of cytotoxic agents and clinical benefits
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Hemophilic pseudotumor – a rare complication
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

A combination of the -α3.7 and --MEDII alleles causing hemoglobin H disease in a Brazilian patient
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Isolated skin relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia after allogeneic stem cell transplant
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Mantle cell lymphoma presenting as multiple lymphomatous polyposis of the gastrointestinal tract
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research

Cutaneous granulomatous reaction as the first manifestation of Hodgkin's lymphoma
This study emphasizes the importance of developing more studies on sickle cell disease mortality, so that it may be possible to profile gene carriers and give health professionals more data to strategize the delivery o f more effective assistance to these individuals. Despite the early diagnosis of sickle cell disease by the Neonatal Screening Program and the use of preventive and therapeutic measures (penicillin, immunization and hydroxyurea), mortality by sickle cell disease on the world stage is still significa nt. (Source: Revista Brasileira de Hematologia e Hemoterapia)
Source: Revista Brasileira de Hematologia e Hemoterapia - April 3, 2017 Category: Hematology Source Type: research