Serial blood sampling effects in rat embryo-fetal development studies for toxicokinetics
Publication date: Available online 20 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Jinsoo Lee, Ji-Seong Jeong, Woojin Kim, Sang Yun Kim, Seung-Jin Lee, Sang-Ki Baek, Jae-Hwan Lee, Eun Ju Jeong, Sang-Yoon Nam, Wook-Joon Yu (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 21, 2021 Category: Toxicology Source Type: research

Letter to the editors regarding “Risk assessments for the insect repellents DEET and picaridin”
Publication date: Available online 18 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Zhaoqing Lyu, Sani Rachman Soleman, Meng Li, Kouji H. Harada (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 19, 2021 Category: Toxicology Source Type: research

A Hazard Evaluation of the Reproductive/Developmental Toxicity of Cobalt in Medical Devices
Publication date: Available online 17 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Andrew D. Monnot, Michael Kovochich, Suren B. Bandara, Jared T. Wilsey, Whitney V. Christian, Gary Eichenbaum, Laura E.L. Perkins, Philippe Hasgall, Maneesh Taneja, Kevin Connor, Jorge Sague, Behrooz Nasseri-Aghbosh, Stephen Marcello, Mark Vreeke, Laurence B. Katz, Edward E. Reverdy, Herbert Thelen, Kenneth Unice (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 19, 2021 Category: Toxicology Source Type: research

Management of Bias and Conflict of Interest among Occupational Exposure Limit Expert Groups
Publication date: Available online 17 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Linda Schenk, Gunnar Johanson (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 19, 2021 Category: Toxicology Source Type: research

An Orthogonal Methods Assessment of Topical Drug Concentrations in Skin and the Impact for Risk Assessment in the Viable Epidermis
Publication date: Available online 16 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Brett D. Hollingshead, Lindsay Tomlinson, Jim Finley, Colleen Doshna, Casey Ritenour, Jason Barricklow, Stacey R. Oppenheimer, Shawn P. O’Neil, Jessica L. Moore, Nathan Heath Patterson, Sarah P. Nicholson, Jeremy L. Norris, Richard M. Caprioli, Kevin Beaumont, Amanda J. King-Ahmad, Saurabh Vispute, Jon C. Cook, Zaher Radi, Maik Schuler (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 16, 2021 Category: Toxicology Source Type: research

Proof of concept efficacy study of intranasal stabilized isoamyl nitrite (SIAN) in rhesus monkeys against acute cyanide poisoning
Publication date: July 2021Source: Regulatory Toxicology and Pharmacology, Volume 123Author(s): Yifei Zhong, Robert E. Raulli, Samir Abtout, Simon Authier, Alexis Ascah, Daniel Lambert, Gloria Gutierrez, Norma L. Cantú, Nadean Gutierrez, Larry Cabell, Joe McDonough, Kelly C. Cakouros, Pablo Gurman, Vladimir Savransky, John Barry (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 15, 2021 Category: Toxicology Source Type: research

Use of Less-than-Lifetime (LTL) Durational Limits for Nitrosamines: Case Study of N-Nitrosodiethylamine (NDEA)
Publication date: Available online 13 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Joel P. Bercu, Melisa Masuda-Herrera, George Johnson, Andreas Czich, Susanne Glowienke, Michelle Kenyon, Rob Thomas, David J. Ponting, Angela White, Kevin Cross, Fernanda Waechter, Maria Augusta C. Rodrigues (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 13, 2021 Category: Toxicology Source Type: research

Toxicological evaluation of a glycan preparation from an enzymatic hydrolysis of Saccharomyces cerevisiae
Publication date: Available online 5 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): G.P. Dillon, A. Yiannikouris, C.A. Moran (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 6, 2021 Category: Toxicology Source Type: research

Inhalation Toxicity of Cyclic Semi-Volatile Methylsiloxanes: Disentangling the Conundrum of Phase-specific Adaptations from Adverse Outcomes
Publication date: Available online 5 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Juergen Pauluhn (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 6, 2021 Category: Toxicology Source Type: research

Classification of chemicals as respiratory allergens based on human data: requirements and practical considerations
Publication date: Available online 5 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Mark A. Pemberton, Ian Kimber (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 6, 2021 Category: Toxicology Source Type: research

A simplified index to quantify the irritation/corrosion potential of chemicals – Part I: Skin
Publication date: Available online 2 April 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Carole Charmeau-Genevois, Satinder Sarang, Mélissa Perea, Charles Eadsforth, Tom Austin, Paul Thomas (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - April 3, 2021 Category: Toxicology Source Type: research

Qualitative Analysis of Actual Standard for Exchange of Nonclinical Data (SEND) Datasets for Data Domains: Proposition from Japan Pharmaceutical Manufacturers Association SEND Taskforce Team on Standardization of Nonclinical Data
Publication date: Available online 20 March 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Gen Sato, Izumi Matsumoto, Mayumi Watanabe, Toshiko Kinomoto, Mikio Nakajima, Masakatsu Yamamoto, Yuki Inoue, Keita Kobayashi, Takashi Tanaharu, Akinori Kiya, Takafumi Yamaguchi, Hitomi Hayashi, Keiko Motoyama, Mutsumi Suzuki, Kazuto Watanabe (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - March 21, 2021 Category: Toxicology Source Type: research

Analysis of Variability in the Rabbit Skin Irritation Assay
Publication date: Available online 20 March 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): John P. Rooney, Neepa Y. Choksi, Patricia Ceger, Amber B. Daniel, James Truax, David Allen, Nicole Kleinstreuer (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - March 21, 2021 Category: Toxicology Source Type: research

Nicotine dosimetry and stability in Cambridge Filter PADs (CFPs) following different smoking regime protocols and storage conditions
Publication date: Available online 18 March 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Pietro Zuccarello, Sonja Rust, Massimo Caruso, Rosalia Emma, Roberta Pulvirenti, Claudia Favara, Riccardo Polosa, Giovanni Li Volti, Margherita Ferrante (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - March 19, 2021 Category: Toxicology Source Type: research

Effect of chain length and branching on the in vitro metabolism of a series of parabens in human liver S9, human skin S9, and human plasma
Publication date: Available online 17 March 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Cindy Obringer, Shengde Wu, John Troutman, Michael Karb, Cathy Lester (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - March 17, 2021 Category: Toxicology Source Type: research