What happened to quinacrine non-surgical female sterilization?
Publication date: Available online 29 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Stephen D. Mumford (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 31, 2021 Category: Toxicology Source Type: research

Aloe-emodin, a hydroxyanthracene derivative, is not genotoxic in an in vivo comet test
Publication date: Available online 29 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Corrado L. Galli, Serena Cinelli, Paola Ciliutti, Gloria Melzi, Marina Marinovich (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 29, 2021 Category: Toxicology Source Type: research

Curing of UV prints – Assessment of possible toxicological hazard for consumers
Publication date: Available online 24 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Melanie Macherey, Ulrike Schuhmacher-Wolz, Harry Belz, Evert H. Delbanco, Kathrin Mohr, Thomas Gude, Eva Kaiser (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 25, 2021 Category: Toxicology Source Type: research

A matched molecular pair (MMP) approach for selecting analogs suitable for structure activity relationship (SAR)-based read across
Publication date: Available online 24 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Cathy C. Lester, Gang Yan (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 25, 2021 Category: Toxicology Source Type: research

The Threshold of Toxicological Concern (TTC) is a pragmatic tool for the safety assessment: Case studies of cosmetic ingredients with low consumer exposure
Publication date: Available online 21 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Dagmar Bury, Julia Head, Detlef Keller, Martina Klaric, Jane Rose (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 21, 2021 Category: Toxicology Source Type: research

Active Pharmaceutical Contaminants in Dietary Supplements: a Tier-Based Risk Assessment Approach
Publication date: Available online 19 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Suren B. Bandara, Ania Urban, Lisa G. Liang, Jillian Parker, Ernest Fung, Andrew Maier (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 21, 2021 Category: Toxicology Source Type: research

Ethyl Acrylate (EA) Exposure and Thyroid Carcinogenicity in Rats and Mice with Relevance to Human Health
Publication date: Available online 18 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Thomas J. Rosol, Raphael J. Witorsch (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 19, 2021 Category: Toxicology Source Type: research

Derivation of an occupational exposure limit for β-glucans
Publication date: Available online 19 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Jillian A. Parker, Corey Boles, Amanda Buerger, Ernest S. Fung, Andrew Maier (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 19, 2021 Category: Toxicology Source Type: research

Afidopyropen: Challenges and Impact of a Toxicokinetic Study Designed to Identify a Point of Inflection from Dose-Proportionality
Publication date: Available online 19 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Anne E. Loccisano, Elaine Freeman, Brandy Riffle, Adriana Doi, Markus Frericks, Ivana Fegert, Eric Fabian (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 19, 2021 Category: Toxicology Source Type: research

Regulatory safety pharmacology and toxicity assessments of a standardized stem extract of Cassia occidentalis Linn. in rodents
Publication date: Available online 19 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Madhav Nilakanth Mugale, Shubha Shukla, Manish K. Chourasia, Kashif Hanif, Aamir Nazir, Sarika Singh, Jiaur R. Gayen, Jagavelu Kumaravelu, Raj Kamal Tripathi, Baisakhi Mohrana, Manoj k. Barthwal, Akhilesh Kumar, Deepak Sharma, Divya Mohan, Anurag K. Srivastava, Sheeba Saji Samuel, Navodayam Kaleti, Sachi Bharti, Anupama Srivastava, Divyansh Sharma (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 19, 2021 Category: Toxicology Source Type: research

Corrigendum to Lay people and experts’ risk perception of pharmaceuticals in the environment in Southwestern Europe [Regul. Toxicol. Pharmacol. (2020) 104783]
Publication date: Available online 15 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Sílvia Luís, Maria Luísa Lima, Lucía Poggio, Juan Ignacio Aragonés, Audrey Courtier, Benoit Roig, Carole Blanchard (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 16, 2021 Category: Toxicology Source Type: research

Case analysis of kinetics investigations in toxicity studies of pesticides to identify the nonlinearity of internal exposure and the influences of nonlinearity on the toxicological interpretation of pesticide residue
Publication date: Available online 12 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Satoshi Machino, Yoko Yokoyama, Toyohiro Egawa, Hiroshi Satoh, Katsuhiro Miyajima, Midori Yoshida, Satoshi Asano, Shogo Ozawa (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 13, 2021 Category: Toxicology Source Type: research

Ni and Cr impurities profile in Valeriana officinalis L., radix-based herbal medicinal product available in Polish pharmacies due to ICH Q3D guideline
Publication date: Available online 13 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Kamil Jurowski, Maria Fołta, Barbara Tatar, Mehmet Berkoz, Mirosław Krośniak (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 13, 2021 Category: Toxicology Source Type: research

Egg residue and depletion in Rhode Island Red hens (Gallus gallus domesticus) following multiple oral doses of Trimethoprim-Sulfamethoxazole
Publication date: Available online 11 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Hiroko Enomoto, Olivia A. Petritz, Andrea E. Thomson, Keven Flammer, Farha Ferdous, Emma Meyer, Lisa A. Tell, Ronald E. Baynes (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 12, 2021 Category: Toxicology Source Type: research

Implementation of the Principles of the 3Rs of Animal Testing at CDER: Past, Present and Future
Publication date: Available online 11 May 2021Source: Regulatory Toxicology and PharmacologyAuthor(s): Ronald L. Wange, Paul C. Brown, Karen L. Davis-Bruno (Source: Regulatory Toxicology and Pharmacology)
Source: Regulatory Toxicology and Pharmacology - May 12, 2021 Category: Toxicology Source Type: research