The triptolide ‐induced apoptosis of osteoclast precursor by degradation of cIAP2 and treatment of rheumatoid arthritis of TNF‐transgenic mice
In conclusion, TPL could induce OCP apoptosis and inhibit OC formation to effectively treat RA by mediating cIAP2 degradation. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 11, 2018 Category: Biochemistry Authors: Shengli Wang,
Zhigang Liu,
Jingchun Wang,
Yifei Wang,
Jianhua Liu,
Xinying Ji,
Xinchun Wang Tags: RESEARCH ARTICLE Source Type: research
Enzymes inhibitors from natural sources with antidiabetic activity: A review
Many medicinal plants products and groups of isolated phytochemicals have shown promising effects as enzyme inhibitors with different mechanism important for new antidiabetic drug design. The most involved mechanisms are inhibition of intestinal α‐glucosidase and amylase; lens aldose reductase; oxidative stress protection; inhibition of formation of AGEs; inhibition ALR; alters enzyme activity of hexokinases and glucose‐6‐phosphate; synthesize and release of insulin; postprandial hyperglycemia inhibition; stimulation of GLUT‐4; and decrease activity of G6P. Natural products have been extensively investigated for a...
Source: Phytotherapy Research - November 11, 2018 Category: Biochemistry Authors: Fiaz Alam,
Zainab Shafique,
Sayyeda Tayyeba Amjad,
Mohammad Hassham Hassan Bin Asad Tags: REVIEW Source Type: research
The triptolide ‐induced apoptosis of osteoclast precursor by degradation of cIAP2 and treatment of rheumatoid arthritis of TNF‐transgenic mice
In conclusion, TPL could induce OCP apoptosis and inhibit OC formation to effectively treat RA by mediating cIAP2 degradation. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 11, 2018 Category: Biochemistry Authors: Shengli Wang,
Zhigang Liu,
Jingchun Wang,
Yifei Wang,
Jianhua Liu,
Xinying Ji,
Xinchun Wang Tags: RESEARCH ARTICLE Source Type: research
The effects of curcumin ‐containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta‐analysis of randomized controlled trials
Besides other benefits, curcumin is getting more recognized for its antioxidant and anti ‐inflammatory properties, highlighting the importance of curcumin application for chronic disease prevention. This systematic review and meta‐analysis of randomized controlled trials (RCTs) was conducted to assess the influence of curcumin‐containing supplements on biomarkers of inflammation a nd oxidative stress. MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials were searched till January 2018 for eligible studies. The selected studies were evaluated for their quality using the Cochrane risk of ...
Source: Phytotherapy Research - November 7, 2018 Category: Biochemistry Authors: Reza Tabrizi,
Sina Vakili,
Maryam Akbari,
Naghmeh Mirhosseini,
Kamran B. Lankarani,
Maryam Rahimi,
Moein Mobini,
Sadegh Jafarnejad,
Zahra Vahedpoor,
Zatollah Asemi Tags: REVIEW Source Type: research
Chemo ‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
Kaempferol, a natural flavonoid present in several plants, possesses a wide range of therapeutic properties such as antioxidant, anticancer, and anti ‐inflammatory. It has a significant role in reducing cancer and can act as a therapeutic agent in the treatment of diseases and ailments such as diabetes, obesity, cardiovascular diseases, oxidative stress, asthma, and microbial contamination disorders. Kaempferol acts through different mechanisms : It induces apoptosis (HeLa cervical cancer cells), decreases cell viability (G2/M phase), downregulates phosphoinositide 3‐kinase (PI3K)/AKT (protein kinase B) and human T‐c...
Source: Phytotherapy Research - November 7, 2018 Category: Biochemistry Authors: Muhammad Imran,
Abdur Rauf,
Zafar Ali Shah,
Farhan Saeed,
Ali Imran,
Muhammad Umair Arshad,
Bashir Ahmad,
Sami Bawazeer,
Muhammad Atif,
Dennis G. Peters,
Mohammad S. Mubarak Tags: REVIEW Source Type: research
The effects of curcumin ‐containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta‐analysis of randomized controlled trials
Besides other benefits, curcumin is getting more recognized for its antioxidant and anti ‐inflammatory properties, highlighting the importance of curcumin application for chronic disease prevention. This systematic review and meta‐analysis of randomized controlled trials (RCTs) was conducted to assess the influence of curcumin‐containing supplements on biomarkers of inflammation a nd oxidative stress. MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials were searched till January 2018 for eligible studies. The selected studies were evaluated for their quality using the Cochrane risk of ...
Source: Phytotherapy Research - November 7, 2018 Category: Biochemistry Authors: Reza Tabrizi,
Sina Vakili,
Maryam Akbari,
Naghmeh Mirhosseini,
Kamran B. Lankarani,
Maryam Rahimi,
Moein Mobini,
Sadegh Jafarnejad,
Zahra Vahedpoor,
Zatollah Asemi Tags: REVIEW Source Type: research
Chemo ‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
Kaempferol, a natural flavonoid present in several plants, possesses a wide range of therapeutic properties such as antioxidant, anticancer, and anti ‐inflammatory. It has a significant role in reducing cancer and can act as a therapeutic agent in the treatment of diseases and ailments such as diabetes, obesity, cardiovascular diseases, oxidative stress, asthma, and microbial contamination disorders. Kaempferol acts through different mechanisms : It induces apoptosis (HeLa cervical cancer cells), decreases cell viability (G2/M phase), downregulates phosphoinositide 3‐kinase (PI3K)/AKT (protein kinase B) and human T‐c...
Source: Phytotherapy Research - November 7, 2018 Category: Biochemistry Authors: Muhammad Imran,
Abdur Rauf,
Zafar Ali Shah,
Farhan Saeed,
Ali Imran,
Muhammad Umair Arshad,
Bashir Ahmad,
Sami Bawazeer,
Muhammad Atif,
Dennis G. Peters,
Mohammad S. Mubarak Tags: REVIEW Source Type: research
Issue Information
No abstract is available for this article. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Tags: ISSUE INFORMATION Source Type: research
Berberine alleviates oxidized low ‐density lipoprotein‐induced macrophage activation by downregulating galectin‐3 via the NF‐κB and AMPK signaling pathways
In conclusion, BBR alleviates ox‐LDL‐induced macrophage activation by downregulating gale ctin‐3 via the NF‐κB and AMPK signaling pathways. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Authors: ChongZhe Pei,
Yi Zhang,
Ping Wang,
BeiJian Zhang,
Lu Fang,
Bo Liu,
Shu Meng Tags: RESEARCH ARTICLE Source Type: research
Transport of salvianolic acid B via the human organic anion transporter 1B1 in the liver
In conclusion, this study demonstrated that OATP1B1 contributes to the transport and accumulation of SAB in the liver. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Authors: Li Cao,
Jian Zhou,
Jinhua Wen Tags: RESEARCH ARTICLE Source Type: research
Berberine alleviates oxidized low ‐density lipoprotein‐induced macrophage activation by downregulating galectin‐3 via the NF‐κB and AMPK signaling pathways
In conclusion, BBR alleviates ox‐LDL‐induced macrophage activation by downregulating gale ctin‐3 via the NF‐κB and AMPK signaling pathways. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Authors: ChongZhe Pei,
Yi Zhang,
Ping Wang,
BeiJian Zhang,
Lu Fang,
Bo Liu,
Shu Meng Tags: RESEARCH ARTICLE Source Type: research
Transport of salvianolic acid B via the human organic anion transporter 1B1 in the liver
In conclusion, this study demonstrated that OATP1B1 contributes to the transport and accumulation of SAB in the liver. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Authors: Li Cao,
Jian Zhou,
Jinhua Wen Tags: RESEARCH ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: Phytotherapy Research)
Source: Phytotherapy Research - November 6, 2018 Category: Biochemistry Tags: ISSUE INFORMATION Source Type: research
Radix Paeoniae Alba increases serum estrogen level and up ‐regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice
Phytotherapy Research, EarlyView. (Source: Phytotherapy Research)
Source: Phytotherapy Research - October 30, 2018 Category: Biochemistry Authors: Ying Xu,
Xin Li,
Ting Chen,
Ya ‐kun Qu,
Hong‐xia Zheng,
Zi‐jia Zhang,
Yuan Zhao,
Na Lin Source Type: research
Histone acetylation increases in response to ferulic, gallic, and sinapic acids acting synergistically in vitro to inhibit Candida albicans yeast ‐to‐hyphae transition
Phytotherapy Research, EarlyView. (Source: Phytotherapy Research)
Source: Phytotherapy Research - October 30, 2018 Category: Biochemistry Authors: Cristiane Rodrigues S. C âmara,
Qinyin Shi,
Matthew Pedersen,
Richard Zbasnik,
Kenneth W. Nickerson,
Vicki Schlegel Source Type: research
