Radioactive iodine: An unappreciated threat to salivary gland function
Thyroid cancer is an endocrine malignancy whose prevalence is increasing in the United States. Nearly 57,000 new cases of thyroid cancer are estimated to be diagnosed in 2017. The standard of care for differentiated thyroid cancer is thyroidectomy followed by ablation of thyroid remnants with high‐dose radioactive iodine (131I). Apart from thyroid glands, 131I accumulates in cells of salivary glands and compromises its function. Xerostomia is, therefore, a frequent and often persistent complaint of patients. Despite adoption of standard preventive measures, parenchymal damage and chronic salivary dysfunction are observed...
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: G Sunavala ‐Dossabhoy Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research

Mobile oral heath technologies based on saliva
We describe several examples from the literature, utilizing different modalities of analysis, applied to several different applications of mobile health monitoring: cortisol monitoring, infectious disease testing, and drugs of abuse. (Source: Oral Diseases)
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: RJ Meagher, E Kousvelari Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research

Cone beam computerized tomography sialography —An emerging novel diagnostic tool for Sjogren's syndrome
(Source: Oral Diseases)
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: DJ Aframian, N Keshet, C Nadler Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research

Comparative analysis of the 2016 ACR ‐EULAR and the 2002 AECG classification criteria for Sjögren's syndrome: Findings from the NIH cohort
ConclusionThere was high agreement between the two classification sets with comparable performance diagnostics. There was no evidence of superior performance value by the new 2016 ACR‐EULAR set over the AECG set, and the two sets were found to be equivalent. Findings from our cohort indicate that 2016 ACR‐EULAR classification could be extended to classification of sSS. (Source: Oral Diseases)
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: M Billings, M Amin Hadavand, I Alevizos Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research

Oral leukoplakia remains a challenging condition
Crispian Scully had many interests in the realm of oral diseases. But oral leukoplakia was one that piqued his curiosity when he was still an academic neophyte and remained a topic which he studied throughout his enormously productive career. It is easy to understand why. While the clinical manifestations of oral leukoplakia are common, we still do not fully understand why one version of the condition is benign, while another, similar in appearance, progresses to a malignancy. The diagnosis of oral leukoplakia is based on expert clinical and histopathological examamination. Management and treatment of leukoplakia remain ch...
Source: Oral Diseases - February 26, 2018 Category: ENT & OMF Authors: A Villa, S Sonis Tags: PROF SCULLY MEMORIAL ISSUE Source Type: research