Changes of Metabolic Disorders Associated Peripheral Cytokine/Adipokine Traffic in Non ‐Obese Chronic Back Patients Responsive to Burst Spinal Cord Stimulation
ConclusionsThis study determined serum changes of metabolic‐associated cytokines/adipokines in non‐obese chronic back pain patients responsive to burst SCS suggesting that neuroinflammation assessment may consider pain‐associated mood, cognition, sleep, and metabolic state. (Source: Neuromodulation)
Source: Neuromodulation - October 24, 2017 Category: Neurology Authors: Sajjad Muhammad, Shafqat R. Chaudhry, Thomas L. Yearwood, Joachim K. Krauss, Thomas M. Kinfe Tags: Clinical Research Source Type: research
Long ‐Term Stability of Short Circuits in Deep Brain Stimulation
ConclusionsAn increasing cumulative incidence demonstrates the clinical importance of short circuits. In the majority of electrodes, short circuits are restricted and remain restricted to two contacts during long‐term stimulation. (Source: Neuromodulation)
Source: Neuromodulation - October 24, 2017 Category: Neurology Authors: Niels Allert, Egle Jusciute, Olga Weirich, Mohammadreza Daryaeitabar, Brit Meike Nolden, Hans Karbe Tags: Clinical Research Source Type: research
In Vitro Magnetic Resonance Imaging Evaluation of Fragmented, Open ‐Coil, Percutaneous Peripheral Nerve Stimulation Leads
Neuromodulation: Technology at the Neural Interface, EarlyView. (Source: Neuromodulation)
Source: Neuromodulation - October 23, 2017 Category: Neurology Source Type: research
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Neuromodulation: Technology at the Neural Interface, Ahead of Print. (Source: Neuromodulation)
Source: Neuromodulation - October 23, 2017 Category: Neurology Source Type: research
In Vitro Magnetic Resonance Imaging Evaluation of Fragmented, Open ‐Coil, Percutaneous Peripheral Nerve Stimulation Leads
ConclusionsMRI may be performed safely in patients with retained lead fragments at 1.5 Tesla using the specific conditions of this study (i.e., MR Conditional). Due to possible excessive temperature rises at 3 Tesla, performing MRI at that field strength is currently inadvisable. (Source: Neuromodulation)
Source: Neuromodulation - October 23, 2017 Category: Neurology Authors: Frank G. Shellock, Armaan Zare, Brian M. Ilfeld, John Chae, Robert B. Strother Tags: Basic Research Source Type: research
Avoiding Internal Capsule Stimulation With a New Eight ‐Channel Steering Deep Brain Stimulation Lead
Neuromodulation: Technology at the Neural Interface, EarlyView. (Source: Neuromodulation)
Source: Neuromodulation - October 15, 2017 Category: Neurology Source Type: research
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Neuromodulation: Technology at the Neural Interface, Ahead of Print. (Source: Neuromodulation)
Source: Neuromodulation - October 15, 2017 Category: Neurology Source Type: research
Avoiding Internal Capsule Stimulation With a New Eight ‐Channel Steering Deep Brain Stimulation Lead
The objective of this study is to assess the performances of a new eight channel steering‐DBS lead and compare this with a conventional cylindrical contact (CC) lead.
ApproachThe two leads were evaluated in a finite element electric field model combined with multicompartment neuron and axon models, representing the internal capsule (IC) fibers and subthalamic nucleus (STN) cells. We defined the optimal stimulation setting as the configuration that activated the highest percentage of STN cells, without activating any IC fibers. With this criterion, we compared monopolar stimulation using a single contact of the steering...
Source: Neuromodulation - October 15, 2017 Category: Neurology Authors: Kees J. van Dijk, Rens Verhagen, Lo J. Bour, Ciska Heida, Peter H. Veltink Tags: Basic Research Source Type: research
Field Distribution of Transcranial Static Magnetic Stimulation in Realistic Human Head Model
Neuromodulation: Technology at the Neural Interface, EarlyView. (Source: Neuromodulation)
Source: Neuromodulation - October 10, 2017 Category: Neurology Source Type: research
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Neuromodulation: Technology at the Neural Interface, Ahead of Print. (Source: Neuromodulation)
Source: Neuromodulation - October 10, 2017 Category: Neurology Source Type: research
Intrathecal Trialing of Continuous Infusion Combination Therapy With Hydromorphone and Bupivacaine in Failed Back Surgery Patients
ConclusionsPatients with refractory low back pain due to FBSS who underwent successful combination IT trial with hydromorphone and bupivacaine infused through a temporary IT catheter had significantly improved pain intensity scores following permanent implant. Higher pre‐trial MEDD was correlated with higher trial and post‐implant opioid doses and higher rates of opioid dose escalation post‐implant. (Source: Neuromodulation)
Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Ryan J. Galica, Salim M. Hayek, Elias Veizi, Matthew T. McEwan, Sivakanth Katta, Omar Ali, Nida Aziz, Nidhi Sondhi Tags: Clinical Research Source Type: research
Cost ‐Effectiveness Modeling of Repetitive Transcranial Magnetic Stimulation Compared to Electroconvulsive Therapy for Treatment‐Resistant Depression in Singapore
ConclusionsrTMS was a cost‐effective treatment compared to ECT in TRD over one year. The cost‐effectiveness of rTMS was attenuated when ECT was used in the outpatient setting. (Source: Neuromodulation)
Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Ying Jiao Zhao, Phern Chern Tor, Ai Leng Khoo, Monica Teng, Boon Peng Lim, Yee Ming Mok Tags: Basic Research Source Type: research
Dorsal Root Ganglion Stimulation Used for the Treatment of Chronic Neuropathic Pain in the Groin: A Single ‐Center Study With Long‐Term Prospective Results in 34 Cases
ConclusionIn this study, DRGS proved an efficient long‐term method for the treatment of chronic neuropathic groin pain and we strongly recommend its use. (Source: Neuromodulation)
Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Matthias Hubert Morgalla, Anil Bolat, Marcos Fortunato, Guilherme Lepski, Bankim Subhash Chander Tags: Clinical Research Source Type: research
Spinal Cord Stimulation for Treating Chronic Pain: Reviewing Preclinical and Clinical Data on Paresthesia ‐Free High‐Frequency Therapy
ConclusionsTo fully understand and utilize paresthesia‐free HF‐SCS, mechanistic study and translational research will be very important, with increasing collaboration between basic science and clinical communities to design better trials and optimize the therapy based on mechanistic findings from effective preclinical models and approaches. Future research in these vital areas may include preclinical and clinical components conducted in parallel to optimize the potential of this technology. (Source: Neuromodulation)
Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Krishnan Chakravarthy, Hira Richter, Paul J. Christo, Kayode Williams, Yun Guan Tags: Review Article Source Type: research
Comparison of the Battery Life of Nonrechargeable Generators for Deep Brain Stimulation
ConclusionThe battery life of the new model was significantly shorter than that of the previous model. A lower battery capacity is the most likely reason, since current consumption was similar in both groups. (Source: Neuromodulation)
Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Ann ‐Kristin Helmers, Isabel Lübbing, Günther Deuschl, Karsten Witt, Michael Synowitz, Hubertus Maximilian Mehdorn, Daniela Falk Tags: Clinical Research Source Type: research
