Intrathecal Trialing of Continuous Infusion Combination Therapy With Hydromorphone and Bupivacaine in Failed Back Surgery Patients

ConclusionsPatients with refractory low back pain due to FBSS who underwent successful combination IT trial with hydromorphone and bupivacaine infused through a temporary IT catheter had significantly improved pain intensity scores following permanent implant. Higher pre‐trial MEDD was correlated with higher trial and post‐implant opioid doses and higher rates of opioid dose escalation post‐implant.

Source: Neuromodulation - October 1, 2017 Category: Neurology Authors: Ryan J. Galica, Salim M. Hayek, Elias Veizi, Matthew T. McEwan, Sivakanth Katta, Omar Ali, Nida Aziz, Nidhi Sondhi Tags: Clinical Research Source Type: research