In vitro biofilms and antifungal susceptibility of dermatophyte and non ‐dermatophyte molds involved in foot mycosis
ConclusionThese findings can help clinicians to develop the appropriate therapy of foot mycosis.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 22, 2017 Category: Research Authors: Nourch éne Toukabri, Serena Corpologno, Marie‐Elisabeth Bougnoux, Dalenda El Euch, Najla Sadfi‐Zouaoui, Giovanna Simonetti Tags: Original Article Source Type: research
Issue Information
(Source: Mycoses)
Source: Mycoses - September 22, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research
Cover Image
The cover image, by Marcela Guevara‐Suarez et al., is based on the Original Article Four new species of Talaromyces from clinical sources, DOI: 10.1111/myc.12640. (Source: Mycoses)
Source: Mycoses - September 22, 2017 Category: Research Tags: COVER IMAGE Source Type: research
Sensitisation to fungi in atopic dermatitis patients older 14 years of age and the relation to the occurrence of food hypersensitivity reactions
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 22, 2017 Category: Research Authors: J. Čelakovská, J. Bukač, K. Ettler, J Vaneckova, I. Krcmova, K. Ettlerova Tags: Original Article Source Type: research
Prevalence, virulence factors and antifungal susceptibility of Candida spp. isolated from bloodstream infections in a tertiary care hospital in Brazil
In conclusion, although the C. glabrata incidence was higher than that usually described in Brazil, its increase was previously observed in studies conducted worldwide. Furthermore, the azole resistance of the C. albicans isolate could be due to previous exposure to these antifungals. These results highlight the importance of epidemiological studies and will facilitate an improved understanding of candidemia in the studied hospital. (Source: Mycoses)
Source: Mycoses - September 22, 2017 Category: Research Authors: Heliara Maria Spina Canela, B árbara Cardoso, Lucia Helena Vitali, Harnoldo Colares Coelho, Roberto Martinez, Márcia Eliana da Silva Ferreira Tags: ORIGINAL ARTICLE Source Type: research
Microbial epidemiology of candidaemia in neonatal and paediatric intensive care units at the Children's Medical Center, Tehran
Summary
Invasive candidiasis is a major cause of morbidity and mortality in children. However, limited data are available on the epidemiology of this infection in paediatric settings in Iran. The aim of this study was to determine the prevalence, microbial epidemiology, risk factors and clinical outcomes associated with candidaemia in intensive care units at the Children's Medical Center, Tehran, Iran. All blood and other normally sterile specimen cultures positive for Candida species were included. Isolates were identified by morphological and molecular methods. Unidentified/doubtful yeast isolates were subjected to ITS s...
Source: Mycoses - September 22, 2017 Category: Research Authors: Arezu Charsizadeh, Hossein Mirhendi, Bahram Nikmanesh, Hamid Eshaghi, Koichi Makimura Tags: ORIGINAL ARTICLE Source Type: research
Susceptibility of Malassezia pachydermatis to aminoglycosides
This study provides evidence of high in vitro activity of the aminoglycosides—gentamicin, tobramycin, netilmicin and framycetin against M. pachydermatis. For gentamicin Etest® showed similar values of MIC50 y MIC90 that the obtained by microdilution method. We considered Etest® method could be a good method for these calculations with aminoglycosides. (Source: Mycoses)
Source: Mycoses - September 19, 2017 Category: Research Authors: Freddy Alejandro Silva, Magnolia Conde ‐Felipe, Inmaculada Rosario, Otilia Ferrer, Fernando Real, Soraya Déniz, Félix Acosta, Daniel Padilla, Begoña Acosta‐Hernández Tags: ORIGINAL ARTICLE Source Type: research
Prospective evaluation of the SeptiFAST multiplex real ‐time PCR assay for surveillance and diagnosis of infections in haematological patients after allogeneic stem cell transplantation compared to routine microbiological assays and an in‐house real‐time PCR method
Summary
We prospectively evaluated a multiplex real‐time PCR assay (SeptiFast, SF) in a cohort of patients undergoing allo‐BMT in comparison to an in‐house PCR method (IH‐PCR). Overall 847 blood samples (mean 8 samples/patient) from 104 patients with haematological malignancies were analysed. The majority of patients had acute leukaemia (62%) with a mean age of 52 years (54% female). Pathogens could be detected in 91 of 847 (11%) samples by SF compared to 38 of 205 (18.5%) samples by BC, and 57 of 847 (6.7%) samples by IH‐PCR. Coagulase‐negative staphylococci (n=41 in SF, n=29 in BC) were the most frequently d...
Source: Mycoses - September 19, 2017 Category: Research Authors: Sandra Elges, Renate Arnold, Oliver Liesenfeld, Grzegorz Kofla, Agata Mikolajewska, Stefan Schwartz, Lutz Uharek, Markus Ruhnke Tags: ORIGINAL ARTICLE Source Type: research
Patient ‐reported outcomes from two randomised studies comparing once‐weekly application of amorolfine 5% nail lacquer to other methods of topical treatment in distal and lateral subungual onychomycosis
The objective of this study was to investigate patient‐reported outcomes (treatment utilisation, adherence and satisfaction) in onychomycosis treated with once‐weekly amorolfine 5% nail lacquer versus once‐daily ciclopirox 8% nail lacquer (Study A) or once‐daily urea 40% ointment/bifonazole 1% cream combination regimen (Study B). Study A: Subjects received amorolfine and ciclopirox on opposite feet for 12 weeks. Study B: Subjects received amorolfine and urea/bifonazole on opposite feet for 6‐7 weeks. Assessments included subject adherence as per label, treatment preference and questionnaire. Study A: More subje...
Source: Mycoses - September 19, 2017 Category: Research Authors: Martin Schaller, Bardur Sigurgeirsson, Marlis Sarkany Tags: ORIGINAL ARTICLE Source Type: research
Isolation of Rhodotorula mucilaginosa from blood cultures in a tertiary care hospital
ConclusionsRhodotorula mucilaginosa may be present on the skin and blood cultures can be contaminated. Fungemia due to R. mucilaginosa is a rare clinical entity which requires risk factors but clinically relevant because of the multiresistant profile. Rhodotorula mucilaginosa shows high MIC values for azoles and echinocandins, therefore amphotericin B and flucytosine must be administered as antifungal therapy.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 18, 2017 Category: Research Authors: Iker Falces ‐Romero, Emilio Cendejas‐Bueno, María Pilar Romero‐Gómez, Julio García‐Rodríguez Tags: Original Article Source Type: research
Clinical Evaluation of the Newly Formatted Lateral ‐Flow Device for Invasive Pulmonary Aspergillosis
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 18, 2017 Category: Research Authors: Martin Hoenigl, Susanne Eigl, Sven Heldt, Wiebke Duettmann, Christopher Thornton, Juergen Prattes Tags: Original Article Source Type: research
In vitro efficacy of disinfectants utilised for skin decolonisation and environmental decontamination during a hospital outbreak with Candida auris
Summary
Candida auris has caused nosocomial infections and transmissions within hospital settings. As little is known about the efficacy of skin and environmental decontamination products to kill C. auris, this study investigated the in vitro activity of chlorine, chlorhexidine, iodine povidone and vaporised hydrogen peroxide products against C. auris. H2O2 vapour showed 96.6%‐100% effective killing of C. auris. All isolates were inhibited by chlorhexidine gluconate concentrations at 0.125%‐1.5% and for iodinated povidone at 0.07%‐1.25%. Other species of Candida were also killed at 1000 ppm chlorine except C. paraps...
Source: Mycoses - September 15, 2017 Category: Research Authors: Alireza Abdolrasouli, Darius Armstrong ‐James, Lisa Ryan, Silke Schelenz Tags: ORIGINAL ARTICLE Source Type: research
Testing the performance of a prototype lateral flow device using bronchoalveolar lavage fluid for the diagnosis of invasive pulmonary aspergillosis in high ‐risk patients
The objective of the study is to compare specificity and sensitivity of the prototype LFD and the galactomannan (GM) enzyme immunoassay in BAL fluid in high‐risk patients. A total of 114 BAL samples from 106 patients at high risk for IPA were studied: 8 patients had proven/probable IPA, 16 had possible IPA and 82 did not have IPA. In patients with proven/probable IPA, specificity of LFD was 94% and GM was 89%; sensitivity of LFD was 38% and GM was 75%. Negative predictive value (NPV) for LFD was 94% and for GM was 98%; positive predictive value (PPV) was 38% for both tests. The use of anti‐mould prophylaxis did not aff...
Source: Mycoses - September 14, 2017 Category: Research Authors: Caroline G. Castillo, Carol A. Kauffman, Jingyi Zhai, Hui Jiang, Stephanie M. Agozino, Marisa H. Miceli Tags: ORIGINAL ARTICLE Source Type: research
Prevalence of onychomycosis among patients with nail psoriasis who are not receiving immunosuppressive agents: Results of a pilot study
Summary
Nail psoriasis and onychomycosis can often be hard to differentiate clinically and may coexist, complicating each other's course. The aim of this study was to determine the prevalence of onychomycosis among patients with nail psoriasis not being treated with immunosuppressive agents, which constitute an independent risk factor for fungal infections. A cross‐sectional study was performed. All adult patients with nail psoriasis who were not receiving antifungal and/or immunosuppressive treatment were recruited at the 2nd University Dermatology Department of Aristotle University of Thessaloniki from 10/2016 till 02/...
Source: Mycoses - September 6, 2017 Category: Research Authors: Aikaterini Tsentemeidou, Timoleon ‐Achilleas Vyzantiadis, Aikaterini Kyriakou, Dimitrios Sotiriadis, Aikaterini Patsatsi Tags: ORIGINAL ARTICLE Source Type: research
Role of oral nystatin prophylaxis in cardiac surgery with prolongedextracorporeal circulation
Summary
Duration >120 minutes of extracorporeal circulation (ECC) during cardiopulmonary bypass procedure was associated to an increased risk of candidemia in the intensive care unit (ICU). To evaluate oral nystatin prophylaxis in cardiac surgery considering its exclusive effect on Candida, in the absence of systemic effects and selection of resistant strains to polyene. We conducted an observational study in the postcardiac surgery ICU of Policlinico “Umberto I” of Rome. From January 2014, all patients with a prolonged ECC >120 minutes were systematically treated with oral nystatin (Prophylaxis group). This g...
Source: Mycoses - September 6, 2017 Category: Research Authors: Alessandro Russo, Giovanni Carriero, Alessio Farcomeni, Giancarlo Ceccarelli, Luigi Tritapepe, Mario Venditti Tags: ORIGINAL ARTICLE Source Type: research
