Inflammation and oxidative stress in corneal tissue in experimental keratitis due to Fusarium solani: amelioration following topical therapy with voriconazole and epigallocatechin gallate
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 24, 2017 Category: Research Authors: Vasanthakumar Vasantha Ruban, Archana P. Teresa, Mahalingam Sundararajan, Pitchairaj Geraldine, Philip Aloysius Thomas Tags: Original Article Source Type: research
Isolation of Candida auris from 9 patients in Central America: Importance of accurate diagnosis and susceptibility testing
This report describes 9 patients from whom C. auris was isolated at a hospital in Panama City, Panama, the first such cases in Central America, and highlights the challenges of accurate identification and methods for susceptibility testing. (Source: Mycoses)
Source: Mycoses - October 16, 2017 Category: Research Authors: Ana Belen Ara úz, Diego H. Caceres, Erika Santiago, Paige Armstrong, Susan Arosemena, Carolina Ramos, Andres Espinosa‐Bode, Jovanna Borace, Lizbeth Hayer, Israel Cedeño, Brendan R. Jackson, Nestor Sosa, Elizabeth L. Berkow, Shawn R. Lockhart, Amalia R Tags: ORIGINAL ARTICLE Source Type: research
In vitro biofilms and antifungal susceptibility of dermatophyte and non ‐dermatophyte moulds involved in foot mycosis
Summary
Tinea pedis and onychomycosis are among the commonest fungal diseases in the world. Dermatophytes and, less frequently, non‐dermatophyte moulds are aetiological agents of foot mycosis and are capable of forming biofilms. Fungal biofilm has demonstrated increasing drug resistance. This work aims to evaluate, in vitro, the ability to form biofilm and the susceptibility to antifungal drugs of sessile dermatophytes and non‐dermatophyte moulds involved in foot mycosis. Thirty‐six dermatophytes and non‐dermatophyte moulds isolated from Tunisian patients with foot mycoses, and identified with MALDI‐TOF have been...
Source: Mycoses - October 15, 2017 Category: Research Authors: Nourch éne Toukabri, Serena Corpologno, Marie‐Elisabeth Bougnoux, Dalenda El Euch, Najla Sadfi‐Zouaoui, Giovanna Simonetti Tags: ORIGINAL ARTICLE Source Type: research
Increasing candidemia incidence from 2004 to 2015 with a shift in epidemiology in patients pre ‐exposed to antifungals
ConclusionsCandidemia incidence increased in the whole hospital, driven by ICUs. Surveillance of candidemia epidemiology on a local scale is of high value to guide empirical treatment strategies.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 12, 2017 Category: Research Authors: Berdieke Goemaere, Pierre Becker, Eric Van Wijngaerden, Johan Maertens, Isabel Spriet, Marijke Hendrickx, Katrien Lagrou Tags: Original Article Source Type: research
Sensitisation to fungi in atopic dermatitis patients over 14 years of age and the relation to the occurrence of food hypersensitivity reactions
Summary
The aim of this study was to evaluate if there is some relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions in atopic dermatitis patients aged 14 years and older. Complete dermatological and allergological examination was performed in all included patients; the occurrence of food hypersensitivity reactions was recorded and the sensitisation to mixture of fungi was examined (skin prick test, specific IgE). The statistical evaluation of the relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions was performed; 331 patients were in...
Source: Mycoses - October 10, 2017 Category: Research Authors: J. Čelakovská, J. Bukač, K. Ettler, J. Vaneckova, I. Krcmova, K. Ettlerova Tags: ORIGINAL ARTICLE Source Type: research
Use of CSP typing for genotyping of azole ‐resistant and ‐susceptible Aspergillus fumigatus isolates in Iran
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 1, 2017 Category: Research Authors: Mahsa Falahatinejad, Afsane Vaezi, Hamed Fakhim, Mahdi Abastabar, Tahereh Shokohi, Nina Zahedi, Saham Ansari, Jacques F. Meis, Hamid Badali Tags: Original Article Source Type: research
Evaluation of multiplex real ‐time PCR for identifying dermatophytes in clinical samples ‐ a multicentre study
ConclusionsThe multiplex RT‐PCR platform is a rapid and efficient method for identifying dermatophyte species in clinical samples and may serve as a first step in the diagnostic algorithm of superficial fungal infections.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 1, 2017 Category: Research Authors: Shany Sherman, Maya Goshen, Orit Treigerman, Keren Ben ‐Zion, Marie‐Jeanne Carp, Noam Maisler, Inbal Binsky Ehrenreich, Aviva Kimchi, Sara Lifshitz, Gill Smollan, Batya Davidovici, Michael David, Emmilia Hodak, Rina Segal Tags: Original Article Source Type: research
Novel Bi ‐allelic Splice Mutations in CARD9 Causing Adult‐onset Candida Endophthalmitis
ConclusionCARD9 deficiency can present with a phenotype of spontaneous candidal endophthalmitis. We report two novel mutations in CARD9, both affecting splicing, expanding the range of morbid variants causing CARD9 deficiency, emphasizing the importance of both genomic and cDNA sequencing for this condition.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 1, 2017 Category: Research Authors: Christina Gavino, Sibylle Mellinghoff, Oliver A. Cornely, Marija Landekic, Catherine Le, Melanie Langelier, Makan Golizeh, Susanna Proske, Donald C. Vinh Tags: Single Case Report Source Type: research
Overexpression of NLRP3, NLRC4 and AIM2 inflammasomes and their priming ‐associated molecules (TLR2, TLR4, Dectin‐1, Dectin‐2 and NFκB) in Malassezia folliculitis
ConclusionsOur observation suggests that simultaneous activation of NLRP3, NLRC4 and AIM2 inflammasomes may play an important role in the pathogenesis of MF.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 1, 2017 Category: Research Authors: Ni Liang, Yan ‐Ping Yang, Wei Li, Ya‐Yun Wu, Zi‐Wei Zhang, Yun Luo, Yi‐Ming Fan Tags: Original Article Source Type: research
Embryonated chicken eggs: An experimental model for Pythium insidiosum infection
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - October 1, 2017 Category: Research Authors: Camila M. Verdi, Francieli P. K. Jesus, Glaucia Kommers, Pauline C. Ledur, Maria I. Azevedo, Erico S. Loreto, Juliana S. M. Tondolo, Eduardo N. C. Andrade, Karine B. Schlemmer, Sydney H. Alves, Janio M. Santurio Tags: Original Article Source Type: research
Candida bloodstream infections in Serbia: First multicentre report of a national prospective observational survey in intensive care units
Summary
Candida bloodstream infections (BSI) are a significant cause of mortality in intensive care units (ICU), hereof the prospective 12‐months (2014‐2015) hospital‐ and laboratory‐based survey was performed at the Serbian National Reference Medical Mycology Laboratory (NRMML). Candida identification was done by a matrix‐assisted laser desorption/ionisation time‐of‐flight mass spectrometry and a susceptibility test, according to the Clinical and Laboratory Standards Institute methodology. Among nine centres (265 beds; 10 820 patient admissions), four neonatal/paediatric (NICU/PICUs) and five adult centres ...
Source: Mycoses - September 28, 2017 Category: Research Authors: Valentina Arsi ć Arsenijević, Suzana Otašević, Dragana Janić, Predrag Minić, Jovan Matijašević, Deana Medić, Ivanka Savić, Snežana Delić, Suzana Nestorović Laban, Zorica Vasiljević, Mirjana Hadnadjev Tags: ORIGINAL ARTICLE Source Type: research
Candida ‐reactive T cells for the diagnosis of invasive Candida infection of the lumbar vertebral spine
We present the case of a 56‐year‐old patient with HIV‐associated Burkitt lymphoma who developed septic shock during chemotherapy‐induced neutropenia. For the first time, we provide flow cytometry‐based diagnostics with Candida‐reactive T cells for invasive candidiasis with comprehensive MRI imaging. The Candida‐reactive T cell assay has potential to complement current diagnostic assays for invasive Candida infection and thus to support targeted treatment. (Source: Mycoses)
Source: Mycoses - September 26, 2017 Category: Research Authors: Felix C. Koehler, Oliver A. Cornely, Hilmar Wisplinghoff, De ‐Hua Chang, Anne Richter, Philipp Koehler Tags: SINGLE CASE REPORT Source Type: research
PCR ‐based detection of Aspergillus fumigatus and absence of azole resistance due to TR34/L98H in a french multicenter cohort of 137 patients with fungal rhinosinusitis
In this study, we aimed to investigate the prevalence of A. fumigatus azole resistance due to TR34/L98H in a multicentre cohort of patients with FRS. One hundred and thirty‐seven patients with FRS admitted between 2002 and 2016 at four French medical centres were retrospectively enrolled. Clinical and mycological findings were collected. Aspergillus fumigatus and the TR34/L98H alteration conferring azole resistance were investigated directly from clinical samples using the commercial CE‐IVD marked MycoGENIE® A. fumigatus real‐time PCR assay. Fungal ball was the more frequent clinical form (n = 118). Despite the ...
Source: Mycoses - September 26, 2017 Category: Research Authors: Florent Morio, Eric Dannaoui, Taieb Chouaki, Estelle Cateau, Olivier Malard, Pierre Bonfils, Cyril Page, Xavier Dufour, Claire Cottrel, Tamic Erwan, Rose ‐Anne Lavergne, Patrice Le Pape Tags: ORIGINAL ARTICLE Source Type: research
Isolation of Candida auris from nine patients in Central America: Importance of accurate diagnosis and susceptibility testing
This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 25, 2017 Category: Research Authors: Ana B Ara úz, Diego H Caceres, Erika Santiago, Paige Armstrong, Susan Arosemena, Carolina Ramos, Andres Espinosa‐Bode, Jovanna Borace, Lizbeth Hayer, Israel Cedeño, Brendan R Jackson, Nestor Sosa, Elizabeth L Berkow, Shawn R Lockhart, Amalia Rodriguez Tags: Original Article Source Type: research
Reliable differentiation of Pneumocystis pneumonia from Pneumocystis colonization by quantification of Major Surface Glycoprotein gene using real ‐time polymerase chain reaction
ConclusionMSG‐gene based qPCR is a robust tool for the reliable differentiation of Pneumocystis pneumonia from colonization.This article is protected by copyright. All rights reserved. (Source: Mycoses)
Source: Mycoses - September 25, 2017 Category: Research Authors: Shivaprakash M Rudramurthy, Megha Sharma, Madhubala Sharma, Pankaj Rawat, Anup Ghosh, V Lakshmishree, Ritesh Aggarwal, Meenu Singh, Arunaloke Chakrabarti Tags: Original Article Source Type: research
