The DNA methylation status of genes encoding Matrix metalloproteinases and Tissue inhibitors of Matrix metalloproteinases in endometriosis
This study evaluated the regulation of abnormal MMP and TIMP gene expression during endometriosis. Among the two genes families, promoter regions of MMP2, MMP3, MMP7, TIMP3, and TIMP4 were significantly altered in proliferative‐phase endometriotic lesions compared to menstrual cycle‐matched eutopic tissue from endometriosis‐free women. In addition, a negative correlation was found between the DNA methylation status of the promoter region and transcript abundance of MMP2. Our findings suggest that changes in DNA methylation at the promoter region of MMP2 could underlie the changes in its expression in the ectopic endo...
Source: Molecular Reproduction and Development - November 20, 2017 Category: Reproduction Medicine Authors: Longying Tang, Yuqian Xiang, Yaohua Zhou, Jian Mu, Meiqing Zai, Qinghe Xing, Xinzhi Zhao, Lin He, Lei Wang, Xi Dong, Qiaoli Li Tags: RESEARCH ARTICLE Source Type: research

Sperm storage influences the potential for spontaneous acrosome reaction of the sperm in the newt Cynops pyrrhogaster
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 20, 2017 Category: Reproduction Medicine Authors: Shinnosuke Kon, Tae Sato, Daisuke Endo, Tomoe Takahashi, Akio Takaku, Yuni Nakauchi, Fubito Toyama, Victor Benno Meyer ‐Rochow, Eriko Takayama‐Watanabe, Akihiko Watanabe Tags: RESEARCH ARTICLE Source Type: research

Intimate intimas: Positioning of copulatory organs in mating Drosophila
(Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 16, 2017 Category: Reproduction Medicine Authors: Alexandra L. Mattei, Yoshitaka Kamimura, Mariana F. Wolfner Tags: VISIONS: the art of science Source Type: research

Table of Contents, Volume 84, Issue 11, November 2017
(Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 16, 2017 Category: Reproduction Medicine Tags: TABLE OF CONTENTS Source Type: research

The 3 Ws of Bayard T. Storey ‐ Wisdom, wine, and wit
(Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 16, 2017 Category: Reproduction Medicine Authors: Harvey Florman, George Gerton, Gregory Kopf, Pablo Visconti Tags: On the Shoulders of Giants Source Type: research

Molecular Reproduction & Development Volume 84, Issue 11, November 2017
Ctenophores, also known as comb jellies, are non‐bilaterian invertebrates and nearly all are self‐fertile hermaphrodites. Mnemiopsis leidyi is a particularly useful model for the study of cellular, tissue, and organ patterning in ctenophores due to their extreme transparency, as seen in these adults. The locomotory ctene rows, highlighted by iridescence, overlie the germ line, from which gametes and embryos are readily available in large numbers. In this issue, Davidson et al. characterize transcript expression and timing of the maternal‐to‐zygotic transition and accompanying zygotic genome activation during early ...
Source: Molecular Reproduction and Development - November 16, 2017 Category: Reproduction Medicine Tags: ON THE COVER Source Type: research

Genetic expansion of chaperonin ‐containing TCP‐1 (CCT/TRiC) complex subunits yields testis‐specific isoforms required for spermatogenesis in planarian flatworms
Chaperonin ‐containing Tail‐less complex polypeptide 1 (CCT) is a highly conserved, hetero‐oligomeric complex that ensures proper folding of actin, tubulin, and regulators of mitosis. Eight subunits (CCT1‐8) make up this complex, and every subunit has a homolog expressed in the testes and somatic tissu e of the planarian flatwormSchmidtea mediterranea. Gene duplications of four subunits in the genomes ofS. mediterranea and other planarian flatworms created paralogs to CCT1, CCT3, CCT4, and CCT8 that are expressed exclusively in the testes. Functional analyses revealed that each CCT subunit expressed in theS. medite...
Source: Molecular Reproduction and Development - November 10, 2017 Category: Reproduction Medicine Authors: Jenna T. Counts, Tasha M. Hester, Labib Rouhana Tags: RESEARCH ARTICLE Source Type: research

Genetic expansion of chaperonin ‐containing TCP‐1 (CCT/TRiC) complex subunits yields testis‐specific isoforms required for spermatogenesis in planarian flatworms
Molecular Reproduction and Development, EarlyView. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 10, 2017 Category: Reproduction Medicine Source Type: research

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Molecular Reproduction and Development, Ahead of Print. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 10, 2017 Category: Reproduction Medicine Source Type: research

Differential expression of key subunits of SWI/SNF chromatin remodeling complexes in porcine embryos derived in vitro or in vivo
In vitro embryo production is an established method for both humans and animals, but is fraught with inferior development and health issues in offspring born after in vitro fertilization procedures. Analysis of epigenetic changes caused by exposure to in vitro conditions should shed light on potential sources of these phenotypes. Using immunocytochemistry, we investigated the localization and relative abundance of components associated with the SWI/SNF (Switch/Sucrose non ‐fermentable) chromatin‐remodeling complex—including BAF155, BAF170, BAF180, BAF53A, BAF57, BAF60A, BAF45D, ARID1A, ARID1B, ARID2, SNF5, and BRD7...
Source: Molecular Reproduction and Development - November 6, 2017 Category: Reproduction Medicine Authors: Birgit Cabot, Yu ‐Chun Tseng, Jennifer S. Crodian, Ryan Cabot Tags: RESEARCH ARTICLE Source Type: research

Differential expression of key subunits of SWI/SNF chromatin remodeling complexes in porcine embryos derived in vitro or in vivo
Molecular Reproduction and Development, EarlyView. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 6, 2017 Category: Reproduction Medicine Source Type: research

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Molecular Reproduction and Development, Ahead of Print. (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 6, 2017 Category: Reproduction Medicine Source Type: research

The effects of superovulation and reproductive aging on the epigenome of the oocyte and embryo
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 1, 2017 Category: Reproduction Medicine Authors: Kira Lynn Marshall, Roc ío Melissa Rivera Tags: REVIEW ARTICLE Source Type: research

Is there an association between PAWP/WBP2NL sequence, expression, and distribution in sperm cells and fertilization failures in ICSI cycles?
In conclusion, no clear association between PAWP/WBP2NL protein expression in sperm and fertilization outcome in ICSI were observed from this cohort. This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 1, 2017 Category: Reproduction Medicine Authors: Freour T, Barragan M, Torra ‐Massana M, Ferrer‐Vaquer A, Vassena R Tags: RESEARCH ARTICEL Source Type: research

Production of functional sperm by subcutaneous auto ‐grafting of immature testes in rainbow trout
This article is protected by copyright. All rights reserved (Source: Molecular Reproduction and Development)
Source: Molecular Reproduction and Development - November 1, 2017 Category: Reproduction Medicine Authors: Makoto Hayashi, Daika Sakuma, Goro Yoshizaki Tags: RESEARCH ARTICLE Source Type: research